Hirschsprung's disease risk factors: Difference between revisions
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The most potent risk factors for developing Hirschsprung's disease include: | The most potent risk factors for developing Hirschsprung's disease include: | ||
*Having multiple family members affected by the disease<ref name="pmid11986456">{{cite journal |vauthors=Swenson O |title=Hirschsprung's disease: a review |journal=Pediatrics |volume=109 |issue=5 |pages=914–8 |year=2002 |pmid=11986456 |doi= |url=}}</ref> | *Having multiple family members affected by the disease<ref name="pmid11986456">{{cite journal |vauthors=Swenson O |title=Hirschsprung's disease: a review |journal=Pediatrics |volume=109 |issue=5 |pages=914–8 |year=2002 |pmid=11986456 |doi= |url=}}</ref> | ||
*Family history of the long segment variant of the disease <ref name="pmid4224912">{{cite journal |vauthors=Passarge E |title=The genetics of Hirschsprung's disease. Evidence for heterogeneous etiology and a study of sixty-three families |journal=N. Engl. J. Med. |volume=276 |issue=3 |pages=138–43 |year=1967 |pmid=4224912 |doi=10.1056/NEJM196701192760303 |url=}}</ref> | *Family history of the long segment variant of the disease<ref name="pmid4224912">{{cite journal |vauthors=Passarge E |title=The genetics of Hirschsprung's disease. Evidence for heterogeneous etiology and a study of sixty-three families |journal=N. Engl. J. Med. |volume=276 |issue=3 |pages=138–43 |year=1967 |pmid=4224912 |doi=10.1056/NEJM196701192760303 |url=}}</ref> | ||
*Female [[proband]] | *Female [[proband]] | ||
*Male gender | *Male gender | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
The most potent risk factor for Hirschsprung's disease is a strong family history (multiple family members afflicted). Other risk factors include a family history of long segment disease and the proband being female.
Risk factors
The most potent risk factors for developing Hirschsprung's disease include:
- Having multiple family members affected by the disease[1]
- Family history of the long segment variant of the disease[2]
- Female proband
- Male gender
References
- ↑ Swenson O (2002). "Hirschsprung's disease: a review". Pediatrics. 109 (5): 914–8. PMID 11986456.
- ↑ Passarge E (1967). "The genetics of Hirschsprung's disease. Evidence for heterogeneous etiology and a study of sixty-three families". N. Engl. J. Med. 276 (3): 138–43. doi:10.1056/NEJM196701192760303. PMID 4224912.