De Quervain's thyroiditis medical therapy: Difference between revisions
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{{CMG}}; {{AE}} {{MMF}} | {{CMG}}; {{AE}} {{MMF}} | ||
==Overview== | ==Overview== | ||
The mainstay of therapy for de Quervain's thyroiditis is [[aspirin]] or [[Non-steroidal anti-inflammatory drug|non-steroidal anti-inflammatory]] drugs for pain control. [[Beta adrenergic-blocking agents|Beta-adrenergic blockers]] are recommended for the patients who develop [[Thyrotoxicosis|thyrotoxic symptoms]]. [[Corticosteroids]] are usually used in severely ill patients. | The mainstay of therapy for [[de Quervain's thyroiditis]] is [[aspirin]] or [[Non-steroidal anti-inflammatory drug|non-steroidal anti-inflammatory]] drugs for pain control. [[Beta adrenergic-blocking agents|Beta-adrenergic blockers]] are recommended for the patients who develop [[Thyrotoxicosis|thyrotoxic symptoms]]. [[Corticosteroids]] are usually used in severely ill patients. | ||
==Medical Therapy== | ==Medical Therapy== | ||
The drugs used in the treatment of | The drugs used in the treatment of [[de Quervain's thyroiditis]] are:<ref name="pmid20886353">{{cite journal |vauthors=Engkakul P, Mahachoklertwattana P, Poomthavorn P |title=Eponym : de Quervain thyroiditis |journal=Eur. J. Pediatr. |volume=170 |issue=4 |pages=427–31 |year=2011 |pmid=20886353 |doi=10.1007/s00431-010-1306-4 |url=}}</ref><ref name="pmid3427792">{{cite journal |vauthors=Yamamoto M, Saito S, Sakurada T, Fukazawa H, Yoshida K, Kaise K, Kaise N, Nomura T, Itagaki Y, Yonemitsu K |title=Effect of prednisolone and salicylate on serum thyroglobulin level in patients with subacute thyroiditis |journal=Clin. Endocrinol. (Oxf) |volume=27 |issue=3 |pages=339–44 |year=1987 |pmid=3427792 |doi= |url=}}</ref><ref name="pmid8257868">{{cite journal |vauthors=Volpé R |title=The management of subacute (DeQuervain's) thyroiditis |journal=Thyroid |volume=3 |issue=3 |pages=253–5 |year=1993 |pmid=8257868 |doi= |url=}}</ref> | ||
#[[Asprin]] or [[NSAIDs]]: | #[[Asprin]] or [[Non-steroidal anti-inflammatory drugs|non-steroidal anti-inflammatory drugs (NSAIDs)]]: | ||
#*Aspirin and | #*Aspirin and [[NSAIDs]] are used for pain control. | ||
#[[Beta-adrenergic blocker|Beta adrenergic blockers]]: | #[[Beta-adrenergic blocker|Beta adrenergic blockers]]: | ||
#*Beta-adrenergic blockers such as propranolol and atenolol are used for controlling thyrotoxic symptoms. | #*[[Beta-adrenergic blockers]] such as [[propranolol]] and [[atenolol]] are used for controlling thyrotoxic symptoms. | ||
#[[Corticosteroids]]: | #[[Corticosteroids]]: | ||
#*Corticosteroids usually show a dramatic response in severely ill patients within 24-48 hours. | #*[[Corticosteroids]] usually show a dramatic response in severely ill patients within 24-48 hours. | ||
#[[Levothyroxine]]: | #[[Levothyroxine]]: | ||
#*It is required if the patient develops hypothyroidism following the resolution of the hyperthyroid state. | #*It is required if the patient develops [[hypothyroidism]] following the resolution of the [[hyperthyroid]] state. | ||
Drug | Drug Regimens: | ||
*[[Naproxen]] | *[[Naproxen]]: 500 to 1000 mg per day in two divided doses | ||
*[[Ibuprofen]] 1200 to 3200 mg per day in three or four divided doses | *[[Ibuprofen]]: 1200 to 3200 mg per day in three or four divided doses | ||
*[[Prednisone]] 40 mg per day orally | *[[Prednisone]]: 40 mg per day orally | ||
*[[Levothyroxine (oral)|Synthetic levothyroxine]] (L-T4) 1.6–1.8 μg/kg | *[[Levothyroxine (oral)|Synthetic levothyroxine]] (L-T4): 1.6–1.8 μg/kg per day orally | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 19:37, 18 August 2017
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De Quervain's thyroiditis Microchapters |
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Differentiating De Quervain's thyroiditis from other Diseases |
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Diagnosis |
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Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The mainstay of therapy for de Quervain's thyroiditis is aspirin or non-steroidal anti-inflammatory drugs for pain control. Beta-adrenergic blockers are recommended for the patients who develop thyrotoxic symptoms. Corticosteroids are usually used in severely ill patients.
Medical Therapy
The drugs used in the treatment of de Quervain's thyroiditis are:[1][2][3]
- Asprin or non-steroidal anti-inflammatory drugs (NSAIDs):
- Aspirin and NSAIDs are used for pain control.
- Beta adrenergic blockers:
- Beta-adrenergic blockers such as propranolol and atenolol are used for controlling thyrotoxic symptoms.
- Corticosteroids:
- Corticosteroids usually show a dramatic response in severely ill patients within 24-48 hours.
- Levothyroxine:
- It is required if the patient develops hypothyroidism following the resolution of the hyperthyroid state.
Drug Regimens:
- Naproxen: 500 to 1000 mg per day in two divided doses
- Ibuprofen: 1200 to 3200 mg per day in three or four divided doses
- Prednisone: 40 mg per day orally
- Synthetic levothyroxine (L-T4): 1.6–1.8 μg/kg per day orally
References
- ↑ Engkakul P, Mahachoklertwattana P, Poomthavorn P (2011). "Eponym : de Quervain thyroiditis". Eur. J. Pediatr. 170 (4): 427–31. doi:10.1007/s00431-010-1306-4. PMID 20886353.
- ↑ Yamamoto M, Saito S, Sakurada T, Fukazawa H, Yoshida K, Kaise K, Kaise N, Nomura T, Itagaki Y, Yonemitsu K (1987). "Effect of prednisolone and salicylate on serum thyroglobulin level in patients with subacute thyroiditis". Clin. Endocrinol. (Oxf). 27 (3): 339–44. PMID 3427792.
- ↑ Volpé R (1993). "The management of subacute (DeQuervain's) thyroiditis". Thyroid. 3 (3): 253–5. PMID 8257868.