Acromegaly natural history, complications and prognosis: Difference between revisions
Jump to navigation
Jump to search
| Line 10: | Line 10: | ||
===Natural History=== | ===Natural History=== | ||
*If left untreated, 30% of patients with acromegaly may progress to develop cardiovascular manifestations, pulmonary dysfunction and cerebral complications. These comorbidities will increase the mortality rate.<ref name="pmid19884662">{{cite journal| author=Melmed S| title=Acromegaly pathogenesis and treatment. | journal=J Clin Invest | year= 2009 | volume= 119 | issue= 11 | pages= 3189-202 | pmid=19884662 | doi=10.1172/JCI39375 | pmc=2769196 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19884662 }} </ref> | *If left untreated, 30% of patients with acromegaly may progress to develop cardiovascular manifestations, pulmonary dysfunction, and cerebral complications. These comorbidities will increase the mortality rate.<ref name="pmid19884662">{{cite journal| author=Melmed S| title=Acromegaly pathogenesis and treatment. | journal=J Clin Invest | year= 2009 | volume= 119 | issue= 11 | pages= 3189-202 | pmid=19884662 | doi=10.1172/JCI39375 | pmc=2769196 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19884662 }} </ref> | ||
===Complications=== | ===Complications=== | ||
*Common complications of [disease | *Common complications of acromegaly include: | ||
**[ | **[[Arthritis]] | ||
**[ | ** [[Cardiovascular disease]] | ||
**[ | ** [[Carpal tunnel syndrome]] | ||
** [[Colonic polyps]] | |||
** [[Glucose intolerance]] or [[diabetes]] | |||
** [[High blood pressure]] | |||
** [[Hypopituitarism]] | |||
** [[Sleep apnea]] | |||
** [[Spinal cord compression]] | |||
** [[Uterine fibroids]] | |||
** Vision abnormalities | |||
===Prognosis=== | ===Prognosis=== | ||
| Line 24: | Line 32: | ||
*[Subtype of disease/malignancy] is associated with the most favorable prognosis. | *[Subtype of disease/malignancy] is associated with the most favorable prognosis. | ||
*The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis. | *The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis. | ||
==Prognosis== | ==Prognosis== | ||
Revision as of 15:37, 8 August 2017
|
Acromegaly Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Acromegaly natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Acromegaly natural history, complications and prognosis |
|
FDA on Acromegaly natural history, complications and prognosis |
|
CDC on Acromegaly natural history, complications and prognosis |
|
Acromegaly natural history, complications and prognosis in the news |
|
Blogs on Acromegaly natural history, complications and prognosis |
|
Risk calculators and risk factors for Acromegaly natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
- Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- If left untreated, 30% of patients with acromegaly may progress to develop cardiovascular manifestations, pulmonary dysfunction, and cerebral complications. These comorbidities will increase the mortality rate.[1]
Complications
- Common complications of acromegaly include:
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
- Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
Prognosis
Pituitary surgery is successful in most patients, depending on the size of the tumor and the experience of the surgeon. Without treatment the symptoms will get worse, and the risk of cardiovascular disease increases.
References
- ↑ Melmed S (2009). "Acromegaly pathogenesis and treatment". J Clin Invest. 119 (11): 3189–202. doi:10.1172/JCI39375. PMC 2769196. PMID 19884662.