Euthyroid sick syndrome classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The stages reflect the severity of critical illness and are designated mild, moderate, severe, and recovery

• There is no established system for the classification of [disease name].

OR

• [Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].

OR

• [Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3].
• [Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].

OR

• Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.

OR

• If the staging system involves specific and characteristic findings and features:
• According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].

OR

• The staging of [malignancy name] is based on the [staging system].

OR

• There is no established system for the staging of [malignancy name].

Classification

Euthyroid sick syndrome may be classified according to the level of thyroid hormones and the severity of the underlying disease into:

• Mild
• Moderate
• Severe
• Recovery

Euthyroid sick syndrome	T3 (80-180 ng/dl)	T4 (4.6-12 ug/dl)	FT4 (0.7-1.9 ng/dl)	TSH (0.4 to 4.0mIU/L)	Reverse T3 (90 to 350pg/mL)
Mild euthyroid sick syndrome	↓	N	N	N	↑
Moderate euthyroid sick syndrome	↓	N	N/↑	N/↑	↑
Severe euthyroid sick syndrome	↓	↓	N/↓	↓	↑
Recovery	N/↓	N	N	N	N/↑