Addison's disease history and symptoms: Difference between revisions
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{{CMG}} ; {{AE}} {{ADG}} | {{CMG}} ; {{AE}} {{ADG}} | ||
==Overview== | ==Overview== | ||
Addison disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness or situation. Acute adrenal insufficiency should be considered in patients presenting with abdominal pain, nausea, diarrhea, hypotension, and fever. A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient of addison's disease include recent changes in diet, any signs of postural hypotension | Addison disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful [[illness]] or situation. Acute adrenal insufficiency should be considered in patients presenting with [[abdominal pain]], [[nausea]], [[diarrhea]], [[hypotension]], and [[fever]]. A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient of addison's disease include recent changes in diet, any signs of [[postural hypotension]] and history of [[tuberculosis]] or any exposure to anyone who has been diagnosed with [[tuberculosis]], [[cancer]] and other autoimmune diseases. | ||
==History== | ==History== | ||
A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient of addison's disease include: | A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient of addison's disease include: | ||
*Recent changes in diet | *Recent changes in diet. | ||
*Periods regularity | **Patients with Addison disease often crave salty foods and are often [[Anorexia|anorexic]]. | ||
*Any signs of postural hypotension | *Periods regularity | ||
*Any recent changes in weight | **[[Oligomenorrhea]] or [[amenorrhea]] are features of Addison disease | ||
*History of tuberculosis | *Any signs of [[postural hypotension]] | ||
*History of any cancer | *Any recent changes in [[weight]] | ||
*History of other autoimmune disease, such as Graves disease, Hashimoto thyroiditis, hypoparathyroidism, vitiligo , pernicious anemia, or diabetes mellitus | *History of [[tuberculosis]] or any exposure to anyone who has been diagnosed with tuberculosis. | ||
*Family history of Addison's disease or any other adrenal disorder | *History of any [[cancer]] | ||
*History of other [[Autoimmune disease|autoimmune disease,]] such as [[Graves' disease|Graves disease]], [[Hashimoto's thyroiditis]], [[hypoparathyroidism]], [[vitiligo]] , [[pernicious anemia]], or [[diabetes mellitus]] | |||
*Family history of Addison's disease or any other adrenal disorder. | |||
==Symptoms== | ==Symptoms== | ||
Addison disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness or situation. Acute adrenal insufficiency should be considered in patients presenting with abdominal pain, nausea, diarrhea, hypotension, and fever.<ref name="pmid23633816">{{cite journal |vauthors=Sarkar SB, Sarkar S, Ghosh S, Bandyopadhyay S |title=Addison's disease |journal=Contemp Clin Dent |volume=3 |issue=4 |pages=484–6 |year=2012 |pmid=23633816 |pmc=3636818 |doi=10.4103/0976-237X.107450 |url=}}</ref><ref name="pmid12788587">{{cite journal |vauthors=Arlt W, Allolio B |title=Adrenal insufficiency |journal=Lancet |volume=361 |issue=9372 |pages=1881–93 |year=2003 |pmid=12788587 |doi=10.1016/S0140-6736(03)13492-7 |url=}}</ref> | Addison disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness or situation. Acute adrenal insufficiency should be considered in patients presenting with [[abdominal pain]], [[nausea]], [[diarrhea]], [[hypotension]], and [[fever]].<ref name="pmid23633816">{{cite journal |vauthors=Sarkar SB, Sarkar S, Ghosh S, Bandyopadhyay S |title=Addison's disease |journal=Contemp Clin Dent |volume=3 |issue=4 |pages=484–6 |year=2012 |pmid=23633816 |pmc=3636818 |doi=10.4103/0976-237X.107450 |url=}}</ref><ref name="pmid12788587">{{cite journal |vauthors=Arlt W, Allolio B |title=Adrenal insufficiency |journal=Lancet |volume=361 |issue=9372 |pages=1881–93 |year=2003 |pmid=12788587 |doi=10.1016/S0140-6736(03)13492-7 |url=}}</ref> | ||
===Common Symptoms=== | ===Common Symptoms=== | ||
*Weakness | *[[Weakness]] | ||
*Chronic fatigue | *[[Fatigue|Chronic fatigue]] | ||
*Weight loss | *[[Weight loss]] | ||
*Anorexia | *[[Anorexia]] | ||
*Nausea | *[[Nausea]] | ||
*Vomiting | *[[Vomiting]] | ||
*Diarrhea | *[[Diarrhea]] | ||
*Intolerance of temperature extremes | *Intolerance of temperature extremes | ||
*Abdominal pain | *[[Abdominal pain]] | ||
*Amenorrhea | *[[Amenorrhea]] | ||
*Craving for salty foods | *Craving for salty foods | ||
*Depression | *[[Depression]] | ||
*Dizziness | *[[Dizziness]] | ||
===Symptoms of Addisonian crisis=== | ===Symptoms of Addisonian crisis=== | ||
Symptoms of Addisonian crisis include: | Symptoms of Addisonian crisis include: | ||
*Dizziness, generalized weakness (fatigue) | *[[Dizziness]], [[generalized weakness]] ([[fatigue]]) | ||
*Anorexia | *[[Anorexia]] | ||
*Sharp, sudden pain in the abdomen, legs, or lower back | *Sharp, sudden [[pain]] in the [[abdomen]], [[legs]], or [[lower back]] | ||
*Severe vomiting and diarrhea | *Severe [[vomiting]] and [[diarrhea]] | ||
* | *[[Dehydration]] | ||
*Loss of consciousness | *Loss of [[consciousness]] | ||
*Hypoglycemia | *[[Hypoglycemia]] | ||
==References== | ==References== | ||
Revision as of 00:40, 22 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Addison disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness or situation. Acute adrenal insufficiency should be considered in patients presenting with abdominal pain, nausea, diarrhea, hypotension, and fever. A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient of addison's disease include recent changes in diet, any signs of postural hypotension and history of tuberculosis or any exposure to anyone who has been diagnosed with tuberculosis, cancer and other autoimmune diseases.
History
A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient of addison's disease include:
- Recent changes in diet.
- Patients with Addison disease often crave salty foods and are often anorexic.
- Periods regularity
- Oligomenorrhea or amenorrhea are features of Addison disease
- Any signs of postural hypotension
- Any recent changes in weight
- History of tuberculosis or any exposure to anyone who has been diagnosed with tuberculosis.
- History of any cancer
- History of other autoimmune disease, such as Graves disease, Hashimoto's thyroiditis, hypoparathyroidism, vitiligo , pernicious anemia, or diabetes mellitus
- Family history of Addison's disease or any other adrenal disorder.
Symptoms
Addison disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness or situation. Acute adrenal insufficiency should be considered in patients presenting with abdominal pain, nausea, diarrhea, hypotension, and fever.[1][2]
Common Symptoms
- Weakness
- Chronic fatigue
- Weight loss
- Anorexia
- Nausea
- Vomiting
- Diarrhea
- Intolerance of temperature extremes
- Abdominal pain
- Amenorrhea
- Craving for salty foods
- Depression
- Dizziness
Symptoms of Addisonian crisis
Symptoms of Addisonian crisis include:
- Dizziness, generalized weakness (fatigue)
- Anorexia
- Sharp, sudden pain in the abdomen, legs, or lower back
- Severe vomiting and diarrhea
- Dehydration
- Loss of consciousness
- Hypoglycemia
References
- ↑ Sarkar SB, Sarkar S, Ghosh S, Bandyopadhyay S (2012). "Addison's disease". Contemp Clin Dent. 3 (4): 484–6. doi:10.4103/0976-237X.107450. PMC 3636818. PMID 23633816.
- ↑ Arlt W, Allolio B (2003). "Adrenal insufficiency". Lancet. 361 (9372): 1881–93. doi:10.1016/S0140-6736(03)13492-7. PMID 12788587.