Pheochromocytoma MRI: Difference between revisions
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==Key MRI Findings in Pheochromocytoma== | ==Key MRI Findings in Pheochromocytoma== | ||
Key [[MRI]] findings in pheochromocytoma are:<ref name="radio">Pheochromocytoma. Dr Matt A. Morgan and Dr Frank Gaillard Gold Supporter since June 24, 2015">. Radiopaedia.org 2015.Page http://radiopaedia.org/articles/pheochromocytoma-2</ref> | Key [[MRI]] findings in pheochromocytoma are:<ref name="radio">Pheochromocytoma. Dr Matt A. Morgan and Dr Frank Gaillard Gold Supporter since June 24, 2015">. Radiopaedia.org 2015.Page http://radiopaedia.org/articles/pheochromocytoma-2</ref> | ||
* T1-weighted | * T1-weighted | ||
** Slightly hypointense to the remainder of the [[adrenal gland]], if there is [[necrosis]] and/or [[hemorrhage]] then the signal will be more heterogeneous<ref name="pmid8076587">{{cite journal| author=Bravo EL| title=Evolving concepts in the pathophysiology, diagnosis, and treatment of pheochromocytoma. | journal=Endocr Rev | year= 1994 | volume= 15 | issue= 3 | pages= 356-68 | pmid=8076587 | doi=10.1210/edrv-15-3-356 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8076587 }}</ref> | ** Slightly hypointense to the remainder of the [[adrenal gland]], if there is [[necrosis]] and/or [[hemorrhage]] then the signal will be more heterogeneous<ref name="pmid8076587">{{cite journal| author=Bravo EL| title=Evolving concepts in the pathophysiology, diagnosis, and treatment of pheochromocytoma. | journal=Endocr Rev | year= 1994 | volume= 15 | issue= 3 | pages= 356-68 | pmid=8076587 | doi=10.1210/edrv-15-3-356 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8076587 }}</ref> | ||
* T2-weighted | * T2-weighted | ||
** Markedly hyperintense light bulb sign, helpful in the diagnosis, areas of [[necrosis]]/[[hemorrhage]]/[[calcification]] will alter the signal. | ** Markedly hyperintense light bulb sign, helpful in the diagnosis, areas of [[necrosis]]/[[hemorrhage]]/[[calcification]] will alter the signal.<ref name="pmid80765872">{{cite journal| author=Bravo EL| title=Evolving concepts in the pathophysiology, diagnosis, and treatment of pheochromocytoma. | journal=Endocr Rev | year= 1994 | volume= 15 | issue= 3 | pages= 356-68 | pmid=8076587 | doi=10.1210/edrv-15-3-356 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8076587 }}</ref> | ||
* T1 with [[gadolinium]] contrast: | * T1 with [[gadolinium]] contrast<ref name="pmid22091429">{{cite journal| author=Heinlen JE, Buethe DD, Culkin DJ, Slobodov G| title=Multiple endocrine neoplasia 2a presenting with pheochromocytoma and pituitary macroadenoma. | journal=ISRN Oncol | year= 2011 | volume= 2011 | issue= | pages= 732452 | pmid=22091429 | doi=10.5402/2011/732452 | pmc=3200135 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22091429 }}</ref> | ||
** Heterogenous enhancement is prolonged, persisting for as long as 50 minutes | ** Heterogenous enhancement is prolonged, persisting for as long as 50 minutes. | ||
* | * Increased vascularity and may be bilateral and hemorrhagic changes. | ||
* [[Spin-spin relaxation time|T2]] weighted MRI of the [[head]], [[neck]], and [[chest]], and [[abdomen]] can help localize the [[tumor]]. | |||
* [[Spin-spin relaxation time|T2]] weighted MRI of the [[head]], [[neck]], and [[chest]], and [[abdomen]] can help localize the [[tumor]] | |||
'''Patient #1: Bladder pheochromocytoma''' | '''Patient #1: Bladder pheochromocytoma''' | ||
<gallery> | <gallery> | ||
Revision as of 23:01, 17 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2] Mohammed Abdelwahed M.D[3]
Overview
Head, neck, chest, and abdominal MRI may be helpful in the diagnosis of pheochromocytoma.
Key MRI Findings in Pheochromocytoma
Key MRI findings in pheochromocytoma are:[1]
- T1-weighted
- Slightly hypointense to the remainder of the adrenal gland, if there is necrosis and/or hemorrhage then the signal will be more heterogeneous[2]
- T2-weighted
- Markedly hyperintense light bulb sign, helpful in the diagnosis, areas of necrosis/hemorrhage/calcification will alter the signal.[3]
- T1 with gadolinium contrast[4]
- Heterogenous enhancement is prolonged, persisting for as long as 50 minutes.
- Increased vascularity and may be bilateral and hemorrhagic changes.
- T2 weighted MRI of the head, neck, and chest, and abdomen can help localize the tumor.
Patient #1: Bladder pheochromocytoma
Patient #2: Abdominal pheochromocytoma
References
- ↑ Pheochromocytoma. Dr Matt A. Morgan and Dr Frank Gaillard Gold Supporter since June 24, 2015">. Radiopaedia.org 2015.Page http://radiopaedia.org/articles/pheochromocytoma-2
- ↑ Bravo EL (1994). "Evolving concepts in the pathophysiology, diagnosis, and treatment of pheochromocytoma". Endocr Rev. 15 (3): 356–68. doi:10.1210/edrv-15-3-356. PMID 8076587.
- ↑ Bravo EL (1994). "Evolving concepts in the pathophysiology, diagnosis, and treatment of pheochromocytoma". Endocr Rev. 15 (3): 356–68. doi:10.1210/edrv-15-3-356. PMID 8076587.
- ↑ Heinlen JE, Buethe DD, Culkin DJ, Slobodov G (2011). "Multiple endocrine neoplasia 2a presenting with pheochromocytoma and pituitary macroadenoma". ISRN Oncol. 2011: 732452. doi:10.5402/2011/732452. PMC 3200135. PMID 22091429.