Osteoporosis X-ray

Osteoporosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Osteoporosis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy Life Style Modification Pharmacotherapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Osteoporosis X-ray On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Osteoporosis X-ray All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Osteoporosis X-ray
CDC on Osteoporosis X-ray
Osteoporosis X-ray in the news
Blogs on Osteoporosis X-ray
Directions to Hospitals Treating Osteoporosis
Risk calculators and risk factors for Osteoporosis X-ray

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]

Overview

X-ray may be helpful in the diagnosis of osteoporosis. The main finding on X-ray suggestive of osteoporosis is bone mass loss, identified with decreased bony trabecula in primary stages and then decreased cortical thickness. The most common bones monitored for osteoporosis evidences are femoral neck, lumbar vertebrae, and calcaneus. Plain radiography needs at least 30-50% of bone loss to demonstrate decreased bone density; therefore, it is not a very sensitive modality.

X-ray

X-ray may be helpful in the diagnosis of osteoporosis. The main finding on x-ray suggestive of osteoporosis is bone mass loss, identified with decreased bony trabecula in primary stages and then decreased cortical thickness. The most common bones monitored for osteoporosis evidences are femoral neck, lumbar vertebrae, and calcaneus. Plain radiography needs at least 30-50% of bone loss to demonstrate decreased bone density; therefore, it is not a very sensitive modality.

Vertebra-plana and Dowager's hump - Case courtesy of Radswiki, Radiopaedia.org, rID: 12072

Indications for imaging

Consider vertebral imaging tests for the following individuals:

• All women age 70 and older and all men age 80 and older if BMD T-score at the spine, total hip, or femoral neck is ≤−1.0
• Women age 65 to 69 and men age 70 to 79 if BMD T-score at the spine, total hip, or femoral neck is ≤−1.5
• Postmenopausal women and men age 50 and older with specific risk factors, include:
  • Low-trauma fracture during adulthood (age 50 and older)
  • Historical height loss of 1.5 in or more (4 cm)
  • Prospective height loss of 0.8 in or more (2 cm)
  • Recent or ongoing long-term glucocorticoid treatment
• X-rays of children with idiopathic juvenile osteoporosis (IJO) often show low bone density, fractures of weight-bearing bones, and collapsed or misshapen vertebrae. However, conventional X-rays may not be able to detect osteoporosis until significant bone mass already has been lost. Newer methods such as dual energy x-ray absorptiometry (DXA), and quantitative computed tomography (QCT ) allow for earlier and more accurate diagnosis of low bone mass.

Lumbar vertebrae

• The major findings correlated to osteoporosis in lumbar vertebrae are include:
  • Wedge shape of vertebrae (decreasing anterior aspect of the body)
  • Picture frame vertebrae (decreased cortical bone in periphery)
  • Ghost vertebrae (decreased trabecular bone in the body)
  • Vertebra plana (severe compression fracture)

Femoral neck

• Singh's index: Categorization of femoral neck bone mineral density upon visual scale of the trabecular bone existence on x-ray.
• The Singh's categories include:
  • Grade 1: Thin principle compression trabeculae
  • Grade 2: Principle compression trabeculae
  • Grade 3: Thin principle tensile trabeculae, with discontinuity
  • Grade 4: Thin principle tensile trabeculae, with continuity
  • Grade 5: Thin principle tensile and compression trabeculae
  • Grade 6: Normal appearance
• Reduced density of trabecular bone in the area, which is described by means of Singh's index (grades 3, 2, and 1), could reflect the diagnosis of osteoporosis

Tubular bones

• Osteoporosis in these bones, especially metacarpals and metatarsals, appeared as loss of cortical thickness. However, cortical thickness of less than 25% of entire bone demonstrate osteoporosis.

• 

  Pathological fracture in T12 and L1 (saggital view); Case courtesy of Dr Roberto Schubert, Radiopaedia.org, rID: 17333

• 

  Pathological fracture in T12 and L1 (axial view); Case courtesy of Dr Roberto Schubert, Radiopaedia.org, rID: 17333

• 

  Dowager's hump; Case courtesy of Dr Roberto Schubert, Radiopaedia.org, rID: 18147

• 

  Idiopathic transient osteoporosis of the hip; Case courtesy of Dr Ahmed Abd Rabou, Radiopaedia.org, rID: 22910