Pheochromocytoma other imaging findings: Difference between revisions
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==Other Imaging Findings== | ==Other Imaging Findings== | ||
Other imaging studies may include:<ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_94_toc</ref> | Other imaging studies may include:<ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_94_toc</ref> | ||
* <sup>123</sup>I-[[metaiodobenzylguanidine]] (MIBG) [[scintigraphy]]: | * <sup>123</sup>I-[[metaiodobenzylguanidine]] (MIBG) [[scintigraphy]]: Done in case of negative or inconclusive [[CT]] and [[Magnetic resonance imaging|MRI]]. The uptake of the compound by [[tumor]] cells is analogous to [[norepinephrine]] uptake by [[adrenergic]] [[tissues]]<ref name="pmid1787652">{{cite journal| author=Bravo EL| title=Pheochromocytoma: new concepts and future trends. | journal=Kidney Int | year= 1991 | volume= 40 | issue= 3 | pages= 544-56 | pmid=1787652 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1787652 }}</ref> | ||
* <sup>111</sup>In-[[octreotide]] [[scintigraphy]]<ref name="pmid10197697">{{cite journal| author=Lin JC, Palafox BA, Jackson HA, Cohen AJ, Gazzaniga AB| title=Cardiac pheochromocytoma: resection after diagnosis by 111-indium octreotide scan. | journal=Ann Thorac Surg | year= 1999 | volume= 67 | issue= 2 | pages= 555-8 | pmid=10197697 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10197697 }}</ref> | * <sup>111</sup>In-[[octreotide]] [[scintigraphy]]<ref name="pmid10197697">{{cite journal| author=Lin JC, Palafox BA, Jackson HA, Cohen AJ, Gazzaniga AB| title=Cardiac pheochromocytoma: resection after diagnosis by 111-indium octreotide scan. | journal=Ann Thorac Surg | year= 1999 | volume= 67 | issue= 2 | pages= 555-8 | pmid=10197697 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10197697 }}</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]
Overview
123I-metaiodobenzylguanidine (MIBG) scintigraphy coupled with CT scan imaging can be used for the localization of distant metastasis of pheochromocytoma.
Other Imaging Findings
Other imaging studies may include:[1]
- 123I-metaiodobenzylguanidine (MIBG) scintigraphy: Done in case of negative or inconclusive CT and MRI. The uptake of the compound by tumor cells is analogous to norepinephrine uptake by adrenergic tissues[2]
- 111In-octreotide scintigraphy[3]
- 18F-fluorodeoxyglucose positron emission tomography is more sensitive than I-MIBG
- PET CT has high sensitivity for small lesions and is more sensitive than I-MIBG
- Adrenal venous sampling (AVS) has high false positive results[4]
- Image-guided needle biopsy of suspected pheochromocytoma may be done but it is associated with many surgical complications[5]
References
- ↑ National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_94_toc
- ↑ Bravo EL (1991). "Pheochromocytoma: new concepts and future trends". Kidney Int. 40 (3): 544–56. PMID 1787652.
- ↑ Lin JC, Palafox BA, Jackson HA, Cohen AJ, Gazzaniga AB (1999). "Cardiac pheochromocytoma: resection after diagnosis by 111-indium octreotide scan". Ann Thorac Surg. 67 (2): 555–8. PMID 10197697.
- ↑ Freel EM, Stanson AW, Thompson GB, Grant CS, Farley DR, Richards ML; et al. (2010). "Adrenal venous sampling for catecholamines: a normal value study". J Clin Endocrinol Metab. 95 (3): 1328–32. doi:10.1210/jc.2009-2253. PMID 20061413.
- ↑ Vanderveen KA, Thompson SM, Callstrom MR, Young WF, Grant CS, Farley DR; et al. (2009). "Biopsy of pheochromocytomas and paragangliomas: potential for disaster". Surgery. 146 (6): 1158–66. doi:10.1016/j.surg.2009.09.013. PMID 19958944.