Struma ovarii laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
*Struma ovarii can be diagnosed only based on histopathologic studies. <ref name="pmid24783110">{{cite journal |vauthors=Sinha NK |title=Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary |journal=J Clin Diagn Res |volume=8 |issue=3 |pages=140–1 |year=2014 |pmid=24783110 |pmc=4003614 |doi=10.7860/JCDR/2014/8005.4138 |url=}}</ref> | |||
*Radiological findings, ascites and raised CA 125 levels make it a unique and highly suspicious case of malignancy. <ref name="pmid27355004">{{cite journal |vauthors=Oudoux A, Leblanc E, Beaujot J, Gauthier-Kolesnikov H |title=Treatment and follow-up of malignant struma ovarii: Regarding two cases |journal=Gynecol Oncol Rep |volume=17 |issue= |pages=56–9 |year=2016 |pmid=27355004 |pmc=4913172 |doi=10.1016/j.gore.2016.05.014 |url=}}</ref> <ref name="pmid24783110">{{cite journal |vauthors=Sinha NK |title=Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary |journal=J Clin Diagn Res |volume=8 |issue=3 |pages=140–1 |year=2014 |pmid=24783110 |pmc=4003614 |doi=10.7860/JCDR/2014/8005.4138 |url=}}</ref> | |||
*Histopathologic studies may aid in diagnosing the malignant struma ovarii when there is no evidence of clinical malignancy or metastases. <ref name="pmid12172581">{{cite journal |vauthors=Kabukcuoglu F, Baksu A, Yilmaz B, Aktumen A, Evren I |title=Malignant struma ovarii |journal=Pathol. Oncol. Res. |volume=8 |issue=2 |pages=145–7 |year=2002 |pmid=12172581 |doi=PAOR.2002.8.2.0145 |url=}}</ref> | *Histopathologic studies may aid in diagnosing the malignant struma ovarii when there is no evidence of clinical malignancy or metastases. <ref name="pmid12172581">{{cite journal |vauthors=Kabukcuoglu F, Baksu A, Yilmaz B, Aktumen A, Evren I |title=Malignant struma ovarii |journal=Pathol. Oncol. Res. |volume=8 |issue=2 |pages=145–7 |year=2002 |pmid=12172581 |doi=PAOR.2002.8.2.0145 |url=}}</ref> | ||
*Elevated levels of CA 125 has been reported rarely in approximately only 8-10 cases so far. <ref name="pmid18334015">{{cite journal |vauthors=Mitrou S, Manek S, Kehoe S |title=Cystic struma ovarii presenting as pseudo-Meigs' syndrome with elevated CA125 levels. A case report and review of the literature |journal=Int. J. Gynecol. Cancer |volume=18 |issue=2 |pages=372–5 |year=2008 |pmid=18334015 |doi=10.1111/j.1525-1438.2007.00998.x |url=}}</ref> <ref name="pmid4003614">{{cite journal |vauthors=Boselie F, Leeuwenberg E |title=Birkhoff revisited: beauty as a function of effect and means |journal=Am J Psychol |volume=98 |issue=1 |pages=1–39 |year=1985 |pmid=4003614 |doi= |url=}}</ref> | *Elevated levels of CA 125 has been reported rarely in approximately only 8-10 cases so far. <ref name="pmid18334015">{{cite journal |vauthors=Mitrou S, Manek S, Kehoe S |title=Cystic struma ovarii presenting as pseudo-Meigs' syndrome with elevated CA125 levels. A case report and review of the literature |journal=Int. J. Gynecol. Cancer |volume=18 |issue=2 |pages=372–5 |year=2008 |pmid=18334015 |doi=10.1111/j.1525-1438.2007.00998.x |url=}}</ref> <ref name="pmid4003614">{{cite journal |vauthors=Boselie F, Leeuwenberg E |title=Birkhoff revisited: beauty as a function of effect and means |journal=Am J Psychol |volume=98 |issue=1 |pages=1–39 |year=1985 |pmid=4003614 |doi= |url=}}</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]
Overview
Laboratory findings consistent with the diagnosis of Struma ovarii include histopathologic studies and elevated CA 125 levels
Laboratory Findings
- Struma ovarii can be diagnosed only based on histopathologic studies. [1]
- Radiological findings, ascites and raised CA 125 levels make it a unique and highly suspicious case of malignancy. [2] [1]
- Histopathologic studies may aid in diagnosing the malignant struma ovarii when there is no evidence of clinical malignancy or metastases. [3]
- Elevated levels of CA 125 has been reported rarely in approximately only 8-10 cases so far. [4] [5]
- In cases of metastatic struma ovarii post total thyroidectomy along with radioiodine scanning and radioiodine ablation, the thyroglobulin levels must be monitored as a tumor marker, and diagnostic radioiodine scans should be done to screen for residual or recurrent disease. [6]
References
- ↑ 1.0 1.1 Sinha NK (2014). "Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary". J Clin Diagn Res. 8 (3): 140–1. doi:10.7860/JCDR/2014/8005.4138. PMC 4003614. PMID 24783110.
- ↑ Oudoux A, Leblanc E, Beaujot J, Gauthier-Kolesnikov H (2016). "Treatment and follow-up of malignant struma ovarii: Regarding two cases". Gynecol Oncol Rep. 17: 56–9. doi:10.1016/j.gore.2016.05.014. PMC 4913172. PMID 27355004.
- ↑ Kabukcuoglu F, Baksu A, Yilmaz B, Aktumen A, Evren I (2002). "Malignant struma ovarii". Pathol. Oncol. Res. 8 (2): 145–7. doi:PAOR.2002.8.2.0145 Check
|doi=value (help). PMID 12172581. - ↑ Mitrou S, Manek S, Kehoe S (2008). "Cystic struma ovarii presenting as pseudo-Meigs' syndrome with elevated CA125 levels. A case report and review of the literature". Int. J. Gynecol. Cancer. 18 (2): 372–5. doi:10.1111/j.1525-1438.2007.00998.x. PMID 18334015.
- ↑ Boselie F, Leeuwenberg E (1985). "Birkhoff revisited: beauty as a function of effect and means". Am J Psychol. 98 (1): 1–39. PMID 4003614.
- ↑ McGill JF, Sturgeon C, Angelos P (2009). "Metastatic struma ovarii treated with total thyroidectomy and radioiodine ablation". Endocr Pract. 15 (2): 167–73. doi:10.4158/EP.15.2.167. PMID 19289330.