Cushing's syndrome history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
Symptoms of Cushing's syndrome include rapid [[obesity|weight gain]], particularly of the trunk and face with sparing of the limbs ([[central obesity]]), a round face often referred to as a "[[moon face]]", excess [[sweating]], [[insomnia]], reduced [[libido]], [[impotence]], [[amenorrhoea]], [[infertility]] and psychological disturbances, ranging from [[Euphoria (emotion)|euphoria]] to [[psychosis]]. [[clinical depression|Depression]] and [[anxiety]]. | Symptoms of Cushing's syndrome include rapid [[obesity|weight gain]], particularly of the [[trunk]] and [[face]] with sparing of the [[limbs]] ([[central obesity]]), a [[round face]] often referred to as a "[[moon face]]", excess [[sweating]], [[insomnia]], reduced [[libido]], [[impotence]], [[amenorrhoea]], [[infertility]] and [[Psychological|psychological disturbances]], ranging from [[Euphoria (emotion)|euphoria]] to [[psychosis]]. [[clinical depression|Depression]] and [[anxiety]]. | ||
==Symptoms== | ==Symptoms== | ||
Symptoms of Cushing's syndrome include:<ref name="pmid26156970">{{cite journal |vauthors=Nieman LK |title=Cushing's syndrome: update on signs, symptoms and biochemical screening |journal=Eur. J. Endocrinol. |volume=173 |issue=4 |pages=M33–8 |year=2015 |pmid=26156970 |pmc=4553096 |doi=10.1530/EJE-15-0464 |url=}}</ref> | Symptoms of Cushing's syndrome include:<ref name="pmid26156970">{{cite journal |vauthors=Nieman LK |title=Cushing's syndrome: update on signs, symptoms and biochemical screening |journal=Eur. J. Endocrinol. |volume=173 |issue=4 |pages=M33–8 |year=2015 |pmid=26156970 |pmc=4553096 |doi=10.1530/EJE-15-0464 |url=}}</ref> | ||
* Rapid [[obesity|weight gain]], particularly of the trunk and face with limbs sparing ([[central obesity]]) | * Rapid [[obesity|weight gain]], particularly of the [[trunk]] and [[face]] with [[limbs]] sparing ([[central obesity]]) | ||
*Proximal [[muscle weakness]] | *Proximal [[muscle weakness]] | ||
* A round face often referred to as a "[[moon face]]" | * A [[round face]] often referred to as a "[[moon face]]" | ||
* Excess [[sweating]] | * Excess [[sweating]] | ||
*[[Headache]] | *[[Headache]] | ||
* The excess cortisol may also affect other endocrine systems and cause, for example: | * The excess [[cortisol]] may also affect other [[Endocrine system|endocrine systems]] and cause, for example: | ||
** [[Insomnia]] | ** [[Insomnia]] | ||
** Decreased [[libido]] | ** Decreased [[libido]] | ||
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** [[Amenorrhoea]] | ** [[Amenorrhoea]] | ||
** [[Infertility]] | ** [[Infertility]] | ||
* Patients frequently suffer various psychological disturbances, ranging from [[Euphoria (emotion)|euphoria]] to [[psychosis]]. [[clinical depression|Depression]] and [[anxiety]] are also common.<ref name="The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences">{{cite book |title=The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences |last=Yudofsky |first=Stuart C. |edition=5th |year=2007 |publisher=American Psychiatric Pub, Inc. |isbn=1585622397 }}</ref> | * Patients frequently suffer various [[Psychological|psychological disturbances]], ranging from [[Euphoria (emotion)|euphoria]] to [[psychosis]]. [[clinical depression|Depression]] and [[anxiety]] are also common.<ref name="The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences">{{cite book |title=The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences |last=Yudofsky |first=Stuart C. |edition=5th |year=2007 |publisher=American Psychiatric Pub, Inc. |isbn=1585622397 }}</ref> | ||
Furthermore, [[gastrointestinal]] disturbances, opportunistic infections and impaired wound healing (cortisol is a stress hormone, so it depresses the immune and inflammatory responses). | Furthermore, [[gastrointestinal]] disturbances, [[Opportunistic infection|opportunistic infections]] and [[impaired wound healing]] ([[cortisol]] is a [[stress hormone]], so it depresses the [[immune]] and [[inflammatory]] responses). | ||
[[Osteoporosis]] is also a problem in Cushing's Syndrome, as mentioned before, cortisol evokes a stress-like response. The body's maintenance of bone (and other tissues) is therefore no longer one of its main priorities, so to speak. | [[Osteoporosis]] is also a problem in Cushing's Syndrome, as mentioned before, [[cortisol]] evokes a stress-like response. The body's maintenance of bone (and other tissues) is therefore no longer one of its main priorities, so to speak. | ||
==References== | ==References== | ||
Revision as of 11:56, 24 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
Symptoms of Cushing's syndrome include rapid weight gain, particularly of the trunk and face with sparing of the limbs (central obesity), a round face often referred to as a "moon face", excess sweating, insomnia, reduced libido, impotence, amenorrhoea, infertility and psychological disturbances, ranging from euphoria to psychosis. Depression and anxiety.
Symptoms
Symptoms of Cushing's syndrome include:[1]
- Rapid weight gain, particularly of the trunk and face with limbs sparing (central obesity)
- Proximal muscle weakness
- A round face often referred to as a "moon face"
- Excess sweating
- Headache
- The excess cortisol may also affect other endocrine systems and cause, for example:
- Insomnia
- Decreased libido
- Impotence
- Amenorrhoea
- Infertility
- Patients frequently suffer various psychological disturbances, ranging from euphoria to psychosis. Depression and anxiety are also common.[2]
Furthermore, gastrointestinal disturbances, opportunistic infections and impaired wound healing (cortisol is a stress hormone, so it depresses the immune and inflammatory responses).
Osteoporosis is also a problem in Cushing's Syndrome, as mentioned before, cortisol evokes a stress-like response. The body's maintenance of bone (and other tissues) is therefore no longer one of its main priorities, so to speak.
References
- ↑ Nieman LK (2015). "Cushing's syndrome: update on signs, symptoms and biochemical screening". Eur. J. Endocrinol. 173 (4): M33–8. doi:10.1530/EJE-15-0464. PMC 4553096. PMID 26156970.
- ↑ Yudofsky, Stuart C. (2007). The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences (5th ed.). American Psychiatric Pub, Inc. ISBN 1585622397.