Sheehan's syndrome natural history, complications and prognosis: Difference between revisions
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*The symptoms of Sheehan's syndrome can develop during immediate post-puerperal period to years after delivery. | *The symptoms of Sheehan's syndrome can develop during immediate post-puerperal period to years after delivery. | ||
*It may result in sparing or reversal of gonadotropic dysfunction as few cases of successful pregnancies have been reported following sheehan's syndrome.<ref name="pmid11273296">{{cite journal |vauthors=Zargar AH, Masoodi SR, Laway BA, Sofi FA, Wani AI |title=Pregnancy in Sheehan's syndrome: a report of three cases |journal=J Assoc Physicians India |volume=46 |issue=5 |pages=476–8 |year=1998 |pmid=11273296 |doi= |url=}}</ref><ref name="pmid6745465">{{cite journal |vauthors=Moreira AC, Zanini Maciel LM, Foss MC, Tabosa Veríssimo JM, Iazigi N |title=Gonadotropin secretory capacity in a patient with Sheehan's syndrome with successful pregnancies |journal=Fertil. Steril. |volume=42 |issue=2 |pages=303–5 |year=1984 |pmid=6745465 |doi= |url=}}</ref> | *It may result in sparing or reversal of gonadotropic dysfunction as few cases of successful pregnancies have been reported following sheehan's syndrome.<ref name="pmid11273296">{{cite journal |vauthors=Zargar AH, Masoodi SR, Laway BA, Sofi FA, Wani AI |title=Pregnancy in Sheehan's syndrome: a report of three cases |journal=J Assoc Physicians India |volume=46 |issue=5 |pages=476–8 |year=1998 |pmid=11273296 |doi= |url=}}</ref><ref name="pmid6745465">{{cite journal |vauthors=Moreira AC, Zanini Maciel LM, Foss MC, Tabosa Veríssimo JM, Iazigi N |title=Gonadotropin secretory capacity in a patient with Sheehan's syndrome with successful pregnancies |journal=Fertil. Steril. |volume=42 |issue=2 |pages=303–5 |year=1984 |pmid=6745465 |doi= |url=}}</ref> | ||
*If left untreated,lead to mitral regurgitation, pericardial effusion and diminished LVM, adrenal crisis, pituitay hypopituitarism and empty sella syndrome. | *If left untreated,lead to mitral regurgitation, pericardial effusion and diminished LVM, adrenal crisis, pituitay hypopituitarism and empty sella syndrome.<ref name="pmid27359291">{{cite journal |vauthors=Laway BA, Ramzan M, Allai MS, Wani AI, Misgar RA |title=CARDIAC STRUCTURAL AND FUNCTIONAL ABNORMALITIES IN FEMALES WITH UNTREATED HYPOPITUITARISM DUE TO SHEEHAN SYNDROME: RESPONSE TO HORMONE REPLACEMENT THERAPY |journal=Endocr Pract |volume=22 |issue=9 |pages=1096–103 |year=2016 |pmid=27359291 |doi=10.4158/EP161262.OR |url=}}</ref> | ||
===Complications=== | ===Complications=== | ||
Revision as of 13:17, 22 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Iqra Qamar M.D.[2]
Overview
- Sheehan syndrome, if left untreated lead to mitral regurgitation, pericardial effusion and diminished LVM.[1]
- Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- Sheehan syndrome usually results in anterior pituitary shrinkage within 20 days followed by disappearance of pituitary tissue in 6-8 week resulting in hypopituitarism and empty sella syndrome.
- The symptoms of Sheehan's syndrome can develop during immediate post-puerperal period to years after delivery.
- It may result in sparing or reversal of gonadotropic dysfunction as few cases of successful pregnancies have been reported following sheehan's syndrome.[2][3]
- If left untreated,lead to mitral regurgitation, pericardial effusion and diminished LVM, adrenal crisis, pituitay hypopituitarism and empty sella syndrome.[1]
Complications
- Common complications of [disease name] include:
- Adrenal crisis
- Hypotension
- Hypothyroidism
- Menstrual irregularities
- Empty sella syndrome
Prognosis
- Prognosis is generally good, and results in reversal of symptoms once respective hormones are being replaced.
References
- ↑ 1.0 1.1 Laway BA, Ramzan M, Allai MS, Wani AI, Misgar RA (2016). "CARDIAC STRUCTURAL AND FUNCTIONAL ABNORMALITIES IN FEMALES WITH UNTREATED HYPOPITUITARISM DUE TO SHEEHAN SYNDROME: RESPONSE TO HORMONE REPLACEMENT THERAPY". Endocr Pract. 22 (9): 1096–103. doi:10.4158/EP161262.OR. PMID 27359291.
- ↑ Zargar AH, Masoodi SR, Laway BA, Sofi FA, Wani AI (1998). "Pregnancy in Sheehan's syndrome: a report of three cases". J Assoc Physicians India. 46 (5): 476–8. PMID 11273296.
- ↑ Moreira AC, Zanini Maciel LM, Foss MC, Tabosa Veríssimo JM, Iazigi N (1984). "Gonadotropin secretory capacity in a patient with Sheehan's syndrome with successful pregnancies". Fertil. Steril. 42 (2): 303–5. PMID 6745465.