Addison's disease history and symptoms: Difference between revisions
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{{CMG}} ; {{AE}} {{ADG}} | {{CMG}} ; {{AE}} {{ADG}} | ||
==Overview== | ==Overview== | ||
Addison disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful [[illness]] or situation. Acute adrenal insufficiency should be considered in patients presenting with [[abdominal pain]], [[nausea]], [[diarrhea]], [[hypotension]], and [[fever]]. A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from | Addison disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful [[illness]] or situation. Acute adrenal insufficiency should be considered in patients presenting with [[abdominal pain]], [[nausea]], [[diarrhea]], [[hypotension]], and [[fever]]. A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from a patient with Addison's disease include recent changes in diet, signs of [[postural hypotension]] and history of [[tuberculosis]], or any exposure to someone with [[tuberculosis]], [[cancer]] and other [[autoimmune]] diseases. | ||
==History== | ==History== | ||
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*Recent changes in diet. | *Recent changes in diet. | ||
**Patients with Addison disease often crave salty foods and are often [[Anorexia|anorexic]]. | **Patients with Addison disease often crave salty foods and are often [[Anorexia|anorexic]]. | ||
* | *Irregular [[menstruation]] | ||
**[[Oligomenorrhea]] or [[amenorrhea]] are features of Addison disease | **[[Oligomenorrhea]] or [[amenorrhea]] are features of Addison disease | ||
*Any signs of [[postural hypotension]] | *Any signs of [[postural hypotension]] | ||
*Any recent changes in [[weight]] | *Any recent changes in [[weight]] | ||
*History of [[tuberculosis]] | *History of [[tuberculosis]] or any exposure to someone with [[tuberculosis]]. | ||
*History of | *History of [[malignancy]] | ||
*History of other [[ | *History of other [[autoimmune disease]], such as [[Graves' disease|Graves disease]], [[Hashimoto's thyroiditis]], [[hypoparathyroidism]], [[vitiligo]], [[pernicious anemia]] or [[diabetes mellitus]] | ||
*Family history of Addison's disease or any other adrenal disorder. | *[[Family history]] of Addison's disease or any other [[Adrenal gland|adrenal]] disorder. | ||
==Symptoms== | ==Symptoms== | ||
Addison disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness | Addison's disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness. Acute adrenal insufficiency should be considered in patients presenting with [[abdominal pain]], [[nausea]], [[diarrhea]], [[hypotension]] and [[fever]].<ref name="pmid23633816">{{cite journal |vauthors=Sarkar SB, Sarkar S, Ghosh S, Bandyopadhyay S |title=Addison's disease |journal=Contemp Clin Dent |volume=3 |issue=4 |pages=484–6 |year=2012 |pmid=23633816 |pmc=3636818 |doi=10.4103/0976-237X.107450 |url=}}</ref><ref name="pmid12788587">{{cite journal |vauthors=Arlt W, Allolio B |title=Adrenal insufficiency |journal=Lancet |volume=361 |issue=9372 |pages=1881–93 |year=2003 |pmid=12788587 |doi=10.1016/S0140-6736(03)13492-7 |url=}}</ref> | ||
===Common Symptoms=== | ===Common Symptoms=== | ||
*[[Weakness]] | *[[Weakness]] | ||
Revision as of 17:40, 15 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Addison disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness or situation. Acute adrenal insufficiency should be considered in patients presenting with abdominal pain, nausea, diarrhea, hypotension, and fever. A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from a patient with Addison's disease include recent changes in diet, signs of postural hypotension and history of tuberculosis, or any exposure to someone with tuberculosis, cancer and other autoimmune diseases.
History
A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient of Addison's disease include:[1]
- Recent changes in diet.
- Patients with Addison disease often crave salty foods and are often anorexic.
- Irregular menstruation
- Oligomenorrhea or amenorrhea are features of Addison disease
- Any signs of postural hypotension
- Any recent changes in weight
- History of tuberculosis or any exposure to someone with tuberculosis.
- History of malignancy
- History of other autoimmune disease, such as Graves disease, Hashimoto's thyroiditis, hypoparathyroidism, vitiligo, pernicious anemia or diabetes mellitus
- Family history of Addison's disease or any other adrenal disorder.
Symptoms
Addison's disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness. Acute adrenal insufficiency should be considered in patients presenting with abdominal pain, nausea, diarrhea, hypotension and fever.[2][3]
Common Symptoms
- Weakness
- Chronic fatigue
- Weight loss
- Anorexia
- Nausea
- Vomiting
- Diarrhea
- Intolerance of temperature extremes
- Abdominal pain
- Amenorrhea
- Craving for salty foods
- Depression
- Dizziness
Symptoms of Addisonian crisis
Symptoms of Addisonian crisis include:
- Dizziness, generalized weakness (fatigue)
- Anorexia
- Sharp, sudden pain in the abdomen, legs, or lower back
- Severe vomiting and diarrhea
- Dehydration
- Loss of consciousness
- Hypoglycemia
References
- ↑ Quinkler M (2012). "[Addison's disease]". Med Klin Intensivmed Notfmed (in German). 107 (6): 454–9. doi:10.1007/s00063-012-0112-3. PMID 22907517.
- ↑ Sarkar SB, Sarkar S, Ghosh S, Bandyopadhyay S (2012). "Addison's disease". Contemp Clin Dent. 3 (4): 484–6. doi:10.4103/0976-237X.107450. PMC 3636818. PMID 23633816.
- ↑ Arlt W, Allolio B (2003). "Adrenal insufficiency". Lancet. 361 (9372): 1881–93. doi:10.1016/S0140-6736(03)13492-7. PMID 12788587.