Sheehan's syndrome diagnostic criteria: Difference between revisions
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{{CMG}}; {{AE}}{{IQ}} | {{CMG}}; {{AE}}{{IQ}} | ||
==Overview== | ==Overview== | ||
Diagnosis is made on clinical basis with a recent/remote history of traumatic delivery or delivery complicated by hypotension. | Diagnosis is made on clinical basis with a recent/remote history of traumatic delivery or delivery complicated by [[hypotension]]. | ||
==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
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*Diagnosis is mostly clinical but following steps are required to make the established diagnosis. | *Diagnosis is mostly clinical but following steps are required to make the established diagnosis. | ||
**Detailed medical history | **Detailed medical history | ||
**Measurement of pituitary hormone levels in blood | **Measurement of [[pituitary hormone]] levels in blood | ||
**Pituitary hormone stimulation tests(insulin tolerance, chlorpromazine, metoclopramide and clomiphene citrate stimulation tests)<ref name="pmid6316866">{{cite journal |vauthors=Cunningham SK, Moore A, McKenna TJ |title=Normal cortisol response to corticotropin in patients with secondary adrenal failure |journal=Arch. Intern. Med. |volume=143 |issue=12 |pages=2276–9 |year=1983 |pmid=6316866 |doi= |url=}}</ref><ref name="pmid7962298">{{cite journal |vauthors=Grinspoon SK, Biller BM |title=Clinical review 62: Laboratory assessment of adrenal insufficiency |journal=J. Clin. Endocrinol. Metab. |volume=79 |issue=4 |pages=923–31 |year=1994 |pmid=7962298 |doi=10.1210/jcem.79.4.7962298 |url=}}</ref> | **Pituitary hormone stimulation tests([[Insulin tolerance test|insulin tolerance]], [[chlorpromazine]], [[metoclopramide]] and [[clomiphene citrate]] stimulation tests)<ref name="pmid6316866">{{cite journal |vauthors=Cunningham SK, Moore A, McKenna TJ |title=Normal cortisol response to corticotropin in patients with secondary adrenal failure |journal=Arch. Intern. Med. |volume=143 |issue=12 |pages=2276–9 |year=1983 |pmid=6316866 |doi= |url=}}</ref><ref name="pmid7962298">{{cite journal |vauthors=Grinspoon SK, Biller BM |title=Clinical review 62: Laboratory assessment of adrenal insufficiency |journal=J. Clin. Endocrinol. Metab. |volume=79 |issue=4 |pages=923–31 |year=1994 |pmid=7962298 |doi=10.1210/jcem.79.4.7962298 |url=}}</ref> | ||
**Imaging(MRI preferred on CT) | **Imaging ([[Magnetic resonance imaging|MRI]] preferred on [[CT]]) | ||
==References== | ==References== | ||
Revision as of 23:24, 24 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Iqra Qamar M.D.[2]
Overview
Diagnosis is made on clinical basis with a recent/remote history of traumatic delivery or delivery complicated by hypotension.
Diagnostic Criteria
- There is no specific established diagnostic criteria for Sheehan's syndrome.
- Diagnosis is made on clinical basis with a recent/remote history of traumatic delivery or delivery complicated by hypotension.
- Diagnosis is mostly clinical but following steps are required to make the established diagnosis.
- Detailed medical history
- Measurement of pituitary hormone levels in blood
- Pituitary hormone stimulation tests(insulin tolerance, chlorpromazine, metoclopramide and clomiphene citrate stimulation tests)[1][2]
- Imaging (MRI preferred on CT)
References
- ↑ Cunningham SK, Moore A, McKenna TJ (1983). "Normal cortisol response to corticotropin in patients with secondary adrenal failure". Arch. Intern. Med. 143 (12): 2276–9. PMID 6316866.
- ↑ Grinspoon SK, Biller BM (1994). "Clinical review 62: Laboratory assessment of adrenal insufficiency". J. Clin. Endocrinol. Metab. 79 (4): 923–31. doi:10.1210/jcem.79.4.7962298. PMID 7962298.