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==Physical Examination==
==Physical Examination==
Physical examination of patients with Cushing's syndrome is as follows:
Physical examination of patients with Cushing's syndrome is as follows:<ref name="pmid26156970">{{cite journal |vauthors=Nieman LK |title=Cushing's syndrome: update on signs, symptoms and biochemical screening |journal=Eur. J. Endocrinol. |volume=173 |issue=4 |pages=M33–8 |year=2015 |pmid=26156970 |pmc=4553096 |doi=10.1530/EJE-15-0464 |url=}}</ref>
===Appearance of the patient===
===Appearance of the patient===
*Patients with Cushing's syndrome usually appears [[overweight]].
*Patients with Cushing's syndrome usually appears [[overweight]].

Revision as of 19:10, 29 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Overview

Patients with Cushing's syndrome usually appear obese. Physical examination of patients with Cushing's syndrome is remarkable for moon-like faces, easy bruising, purple skin stria, and hirsutism.

Physical Examination

Physical examination of patients with Cushing's syndrome is as follows:[1]

Appearance of the patient

  • Patients with Cushing's syndrome usually appears overweight.

Vital signs

Head

  • Moon-face is a medical sign where the face swells up into a rounded shape. It is often associated with Cushing's syndrome, which has led to it being known as Cushingoid facies ("Cushings-like face"), or steroid treatment, which has led to the name steroid facies.

Skin

  • Hyperpigmentation - this is due to Melanocyte-Stimulating Hormone production as a byproduct of ACTH synthesis from Proopiomelanocortin (POMC)
  • Telangiectasia (dilation of capillaries)
  • Thinning of the skin (which causes easy bruising)
  • Purple or red striae (the weight gain in Cushing's stretches the skin, which is thin and weakened, causing it to hemorrhage) on the trunk, buttocks, arms, legs or breasts, proximal muscle weakness (hips, shoulders)
  • Hirsutism (facial male-pattern hair growth)

Eye

Neck

  • Growth of fat pads along the collar bone and on the back of the neck (known as a lipodystrophy)
Features of Cushing's syndrome(Image courtesy of Jessica Stevenson, and http://www.physio-pedia.com/File:Cushings-syndrome2.jpg#filelinks)


References

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  1. Nieman LK (2015). "Cushing's syndrome: update on signs, symptoms and biochemical screening". Eur. J. Endocrinol. 173 (4): M33–8. doi:10.1530/EJE-15-0464. PMC 4553096. PMID 26156970.