21-hydroxylase deficiency surgery: Difference between revisions
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== Surgery == | == Surgery == | ||
=== '''Reconstructive surgery''' === | === '''Reconstructive surgery''' === | ||
* Reconstructive [[Gynaecology|gynecologic]] [[surgery]] | * Reconstructive [[Gynaecology|gynecologic]] [[surgery]] in [[Adolescent|adolescents]] or [[Adult|adults]], including clitoroplasty and [[vaginoplasty]]<ref name="pmid9156043">{{cite journal| author=Premawardhana LD, Hughes IA, Read GF, Scanlon MF| title=Longer term outcome in females with congenital adrenal hyperplasia (CAH): the Cardiff experience. | journal=Clin Endocrinol (Oxf) | year= 1997 | volume= 46 | issue= 3 | pages= 327-32 | pmid=9156043 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9156043 }}</ref> | ||
==== '''Surgical adrenalectomy''' ==== | ==== '''Surgical adrenalectomy''' ==== | ||
* The major benefit is lowering [[Adrenal gland|adrenal]] [[androgen]] and [[progesterone]] secretion. However, | * The major benefit is lowering [[Adrenal gland|adrenal]] [[androgen]] and [[progesterone]] secretion. However, it increases dependency on [[glucocorticoid]] and [[mineralocorticoid]] replacement therapy<ref name="pmid22904181">{{cite journal| author=Crocker MK, Barak S, Millo CM, Beall SA, Niyyati M, Chang R et al.| title=Use of PET/CT with cosyntropin stimulation to identify and localize adrenal rest tissue following adrenalectomy in a woman with congenital adrenal hyperplasia. | journal=J Clin Endocrinol Metab | year= 2012 | volume= 97 | issue= 11 | pages= E2084-9 | pmid=22904181 | doi=10.1210/jc.2012-2298 | pmc=3485588 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22904181 }}</ref> | ||
== References == | == References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 17:32, 5 September 2017
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21-hydroxylase deficiency Microchapters |
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Differentiating 21-Hydroxylase Deficiency from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]
Overview
Reconstructive surgery and surgical adrenalectomy.
Surgery
Reconstructive surgery
- Reconstructive gynecologic surgery in adolescents or adults, including clitoroplasty and vaginoplasty[1]
Surgical adrenalectomy
- The major benefit is lowering adrenal androgen and progesterone secretion. However, it increases dependency on glucocorticoid and mineralocorticoid replacement therapy[2]
References
- ↑ Premawardhana LD, Hughes IA, Read GF, Scanlon MF (1997). "Longer term outcome in females with congenital adrenal hyperplasia (CAH): the Cardiff experience". Clin Endocrinol (Oxf). 46 (3): 327–32. PMID 9156043.
- ↑ Crocker MK, Barak S, Millo CM, Beall SA, Niyyati M, Chang R; et al. (2012). "Use of PET/CT with cosyntropin stimulation to identify and localize adrenal rest tissue following adrenalectomy in a woman with congenital adrenal hyperplasia". J Clin Endocrinol Metab. 97 (11): E2084–9. doi:10.1210/jc.2012-2298. PMC 3485588. PMID 22904181.