Hashimoto's thyroiditis other diagnostic studies: Difference between revisions
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The histological analysis in Hashimoto's thyroiditis may show [[inflammatory]] cell infiltration and Hurthle cells. [[FNA|Fine needle aspiration cytology]] helps to differentiate between the [[benign]] and [[malignant]] [[nodules]].<ref name="pmid24434360">{{cite journal |vauthors=Caturegli P, De Remigis A, Rose NR |title=Hashimoto thyroiditis: clinical and diagnostic criteria |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=391–7 |year=2014 |pmid=24434360 |doi=10.1016/j.autrev.2014.01.007 |url=}}</ref><ref name="urlThyroiditis — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJMra021194 |title=Thyroiditis — NEJM |format= |work= |accessdate=}}</ref> | The histological analysis in Hashimoto's thyroiditis may show [[inflammatory]] cell infiltration and Hurthle cells. [[FNA|Fine needle aspiration cytology]] helps to differentiate between the [[benign]] and [[malignant]] [[nodules]].<ref name="pmid24434360">{{cite journal |vauthors=Caturegli P, De Remigis A, Rose NR |title=Hashimoto thyroiditis: clinical and diagnostic criteria |journal=Autoimmun Rev |volume=13 |issue=4-5 |pages=391–7 |year=2014 |pmid=24434360 |doi=10.1016/j.autrev.2014.01.007 |url=}}</ref><ref name="urlThyroiditis — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJMra021194 |title=Thyroiditis — NEJM |format= |work= |accessdate=}}</ref> | ||
===Gross Pathology=== | ===Gross Pathology=== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The histological analysis in Hashimoto's thyroiditis may show inflammatory cell infiltration and Hurthle cells. Fine needle aspiration cytology helps to differentiate between the benign and malignant nodules.
Other Diagnostic Studies
The histological analysis in Hashimoto's thyroiditis may show inflammatory cell infiltration and Hurthle cells. Fine needle aspiration cytology helps to differentiate between the benign and malignant nodules.[1][2]
Gross Pathology
- The gland is usually diffusely enlarged, firm, and slightly lobular. The capsule is intact, and the cut surface is light-tan and has a slight lobular pattern.
- At autopsy, significant subarachnoid hemorrhage from the ruptured berry aneurysm was documented. In addition, the thyroid gland was mildly enlarged and firm. On cut section, the tissue was slightly pale.
Microscopic Pathology
Microscopically there is massive infiltration of the thyroid gland by lymphocytes and plasma cells. Germinal centers can often be seen in the gland. Thyroid follicles are usually absent and the few remaining follicles are devoid of colloid.
References
- ↑ Caturegli P, De Remigis A, Rose NR (2014). "Hashimoto thyroiditis: clinical and diagnostic criteria". Autoimmun Rev. 13 (4–5): 391–7. doi:10.1016/j.autrev.2014.01.007. PMID 24434360.
- ↑ "Thyroiditis — NEJM".