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==Risk factors==
==Risk factors==
Common risk factors that can trigger myxedema coma in patients with hypothyroidism include:
Common risk factors that can trigger myxedema coma in patients with hypothyroidism include:
Hypothermia
*Hypothermia
CVA
*CVA
CHF
*CHF
Infections ( pneumonia, influenza, UTI, sepsis)
*Infections ( pneumonia, influenza, UTI, sepsis)
Drugs ( Anesthestics, narcotics, amidirone, Lithium carbonate) 6486153
*Drugs ( Anesthestics, narcotics, amidirone, Lithium carbonate) 6486153
GI bleeding
*GI bleeding
Metabolic disturbances(Hypoglycemia, hyponatremia, acidosis, hypercalcemia, hypoxemia, hypercapneia)
*Metabolic disturbances(Hypoglycemia, hyponatremia, acidosis, hypercalcemia, hypoxemia, hypercapneia)
 
==History==
==History==



Revision as of 00:14, 20 September 2017

Risk factors

Common risk factors that can trigger myxedema coma in patients with hypothyroidism include:

  • Hypothermia
  • CVA
  • CHF
  • Infections ( pneumonia, influenza, UTI, sepsis)
  • Drugs ( Anesthestics, narcotics, amidirone, Lithium carbonate) 6486153
  • GI bleeding
  • Metabolic disturbances(Hypoglycemia, hyponatremia, acidosis, hypercalcemia, hypoxemia, hypercapneia)

History

  • History of antecedent thyroid disease
  • History of radioiodine therapy or thyroidectomy
  • Discontinuation of medications.

Historical Perspective

  • In 874, Gull was the first physician to describe hypothyroidism under the name myxedema due to its characteristics of swollen skin and its mucin content.
  • In 1883, Semon was the first to establish a relationship between patients undergoing thyroidectomy and later developing symptoms of myxedema.
  • In 1888, Clinical Society of London presented a paper describing that extreme loss of thyroid harmone can lead to cretinism and myxedema.
  • In 1891, Murray was the first physician to discover cure for myxedema by using hypodermic injections of sheep thyroid extract.