Alzheimer's disease MRI: Difference between revisions
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==MRI== | ==MRI== | ||
*Structural MRI of the brain may be helpful in the diagnosis of alzheimer's disease. Characteristic finding on MRI suggestive of alzheimer's disease include: <ref name="pmid22951070">{{cite journal| author=Whitwell JL, Dickson DW, Murray ME, Weigand SD, Tosakulwong N, Senjem ML et al.| title=Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study. | journal=Lancet Neurol | year= 2012 | volume= 11 | issue= 10 | pages= 868-77 | pmid=22951070 | doi=10.1016/S1474-4422(12)70200-4 | pmc=3490201 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22951070 }} </ref> <ref name="pmid1643466">{{cite journal| author=Brook RH| title=Improving practice: the clinician's role. | journal=Br J Surg | year= 1992 | volume= 79 | issue= 7 | pages= 606-7 | pmid=1643466 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1643466 }} </ref> <ref name="pmid17923614">{{cite journal| author=Barkhof F, Polvikoski TM, van Straaten EC, Kalaria RN, Sulkava R, Aronen HJ et al.| title=The significance of medial temporal lobe atrophy: a postmortem MRI study in the very old. | journal=Neurology | year= 2007 | volume= 69 | issue= 15 | pages= 1521-7 | pmid=17923614 | doi=10.1212/01.wnl.0000277459.83543.99 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17923614 }} </ref> | |||
**Reduced hippocampal volume | |||
**Medial temporal lobe atrophy | |||
* | *Findings on MRI in an elderly patient with memory loss demonstrates cerebral volume loss, particularly pronounced in the temporal and parietal lobes, consistent with the clinical impression of Alzheimer disease. | ||
*Multiple white matter T2 hyperintense regions are suggestive of chronic small vessel ischemic change. | *Multiple white matter T2 hyperintense regions are suggestive of chronic small vessel ischemic change. | ||
Revision as of 20:41, 20 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
There are no MRI findings associated with [disease name].
OR
[Location] MRI may be helpful in the diagnosis of [disease name]. Findings on MRI suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].
OR
There are no MRI findings associated with [disease name]. However, a MRI may be helpful in the diagnosis of complications of [disease name], which include [complication 1], [complication 2], and [complication 3].
MRI
- Structural MRI of the brain may be helpful in the diagnosis of alzheimer's disease. Characteristic finding on MRI suggestive of alzheimer's disease include: [1] [2] [3]
- Reduced hippocampal volume
- Medial temporal lobe atrophy
- Findings on MRI in an elderly patient with memory loss demonstrates cerebral volume loss, particularly pronounced in the temporal and parietal lobes, consistent with the clinical impression of Alzheimer disease.
- Multiple white matter T2 hyperintense regions are suggestive of chronic small vessel ischemic change.
References
- ↑ Whitwell JL, Dickson DW, Murray ME, Weigand SD, Tosakulwong N, Senjem ML; et al. (2012). "Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study". Lancet Neurol. 11 (10): 868–77. doi:10.1016/S1474-4422(12)70200-4. PMC 3490201. PMID 22951070.
- ↑ Brook RH (1992). "Improving practice: the clinician's role". Br J Surg. 79 (7): 606–7. PMID 1643466.
- ↑ Barkhof F, Polvikoski TM, van Straaten EC, Kalaria RN, Sulkava R, Aronen HJ; et al. (2007). "The significance of medial temporal lobe atrophy: a postmortem MRI study in the very old". Neurology. 69 (15): 1521–7. doi:10.1212/01.wnl.0000277459.83543.99. PMID 17923614.