Adrenocortical carcinoma MRI: Difference between revisions
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* Large [[Adrenal gland|adrenal]] [[carcinomas]] tend to invade the [[Adrenal gland|adrenal]] vein and [[inferior vena cava]].<ref name="pmid21606258" /> | * Large [[Adrenal gland|adrenal]] [[carcinomas]] tend to invade the [[Adrenal gland|adrenal]] vein and [[inferior vena cava]].<ref name="pmid21606258" /> | ||
* On MRI, ACCs appear isointense to hypointense relative to [[liver]] parenchyma on T1-weighted images and hyperintense relative to [[liver]] [[parenchyma]] on T2-weighted images. | * On MRI, ACCs appear isointense to hypointense relative to [[liver]] parenchyma on T1-weighted images and hyperintense relative to [[liver]] [[parenchyma]] on T2-weighted images.<ref name="pmid216062582">{{cite journal| author=Bharwani N, Rockall AG, Sahdev A, Gueorguiev M, Drake W, Grossman AB et al.| title=Adrenocortical carcinoma: the range of appearances on CT and MRI. | journal=AJR Am J Roentgenol | year= 2011 | volume= 196 | issue= 6 | pages= W706-14 | pmid=21606258 | doi=10.2214/AJR.10.5540 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21606258 }}</ref> | ||
* On [[Chemical shift|chemical-shift]] [[Magnetic resonance imaging|MRI]], the presence of [[intracellular]] [[lipid]] can cause regions of signal loss on out-of-phase images relative to inphase images.<ref>{{Cite journal | * On [[Chemical shift|chemical-shift]] [[Magnetic resonance imaging|MRI]], the presence of [[intracellular]] [[lipid]] can cause regions of signal loss on out-of-phase images relative to inphase images.<ref>{{Cite journal | ||
Revision as of 14:18, 25 September 2017
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Adrenocortical carcinoma Microchapters |
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Differentiating Adrenocortical carcinoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Study |
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Adrenocortical carcinoma MRI On the Web |
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American Roentgen Ray Society Images of Adrenocortical carcinoma MRI |
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Risk calculators and risk factors for Adrenocortical carcinoma MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2] Mohammed Abdelwahed M.D[3]
Overview
MRI scans are helpful in differentiating between adrenal adenoma, carcinoma, and metastatic lesions. Due to the multiplanar capability of MRI, direct invasion of adjacent organs may be better shown.
MRI Findings in adrenocortical carcinoma
- Adrenocortical carcinomas are usually large and appear as heterogeneous masses on both T1- and T2-weighted images owing to the presence of internal hemorrhage and necrosis.[1]
- Adrenocortical carcinoma can contain foci of intracytoplasmic lipid, which results in a loss of signal intensity on out-of-phase images.[2]
- Large adrenal carcinomas tend to invade the adrenal vein and inferior vena cava.[1]
- On MRI, ACCs appear isointense to hypointense relative to liver parenchyma on T1-weighted images and hyperintense relative to liver parenchyma on T2-weighted images.[3]
- On chemical-shift MRI, the presence of intracellular lipid can cause regions of signal loss on out-of-phase images relative to inphase images.[4]
- Inferior vena cava invasion has been reported in 9% to 19% of cases at presentation. Due to the multiplanar capability of MRI, direct invasion of adjacent organs may be better shown.
MRI Examples of adrenocortical carcinoma
Source: Case courtesy of Radswiki, Radiopaedia.org, rID: 11176
References
- ↑ 1.0 1.1 Bharwani N, Rockall AG, Sahdev A, Gueorguiev M, Drake W, Grossman AB; et al. (2011). "Adrenocortical carcinoma: the range of appearances on CT and MRI". AJR Am J Roentgenol. 196 (6): W706–14. doi:10.2214/AJR.10.5540. PMID 21606258.
- ↑ Ng L, Libertino JM (2003). "Adrenocortical carcinoma: diagnosis, evaluation and treatment". J Urol. 169 (1): 5–11. doi:10.1097/01.ju.0000030148.59051.35. PMID 12478091.
- ↑ Bharwani N, Rockall AG, Sahdev A, Gueorguiev M, Drake W, Grossman AB; et al. (2011). "Adrenocortical carcinoma: the range of appearances on CT and MRI". AJR Am J Roentgenol. 196 (6): W706–14. doi:10.2214/AJR.10.5540. PMID 21606258.
- ↑ Gwenaelle Abiven, Joel Coste, Lionel Groussin, Philippe Anract, Frederique Tissier, Paul Legmann, Bertrand Dousset, Xavier Bertagna & Jerome Bertherat (2006). "Clinical and biological features in the prognosis of adrenocortical cancer: poor outcome of cortisol-secreting tumors in a series of 202 consecutive patients". The Journal of clinical endocrinology and metabolism. 91 (7): 2650–2655. doi:10.1210/jc.2005-2730. PMID 16670169. Unknown parameter
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