Myxedema coma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

History

• History of thyroid disease
• History of radioiodine therapy or thyroidectomy,
• Thyroid hormone therapy that was inappropriately discontinued

Symptoms

Symptoms of myxedema coma can be summarized in the following table

Organ system involved	Manifestations
CNS	Lethargy Poor memory Cognitive dysfunction Depression Psychosis Hypothermia Focal or generalized seizures
Cardiovascular	SOB Chest pain
Pulmonary
Gastro-intestinal	Anorexia Nausea Abdominal pain Constipation
Renal and electrolyte	Bladder atony with urinary retention
Systemic	Presence of normal temperature in myxedema indicates presence of infection