Sandbox:Amd: Difference between revisions

Revision as of 20:19, 25 September 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]

Disease	Clinical history/findings							Causes	Investigations/ Laboratory findings
	Hypotension	Skin pigmentation/ findings	Fatigue	Anorexia/ Weightloss	Abdominal pain	Muscle weakness	Other history/ findings	Causes	Hypo natremia	Cortisol levels	Gold Standard
Differentiating amongst adrenal insufficiencies
Primary adrenal insufficiency	✔	✔	✔	✔	✔	✔		Autoimmune/idiopathic Infections- Tuberculosis, histoplasmosis	✔	↓	Cosyntropin/ ACTH stimulation test
Secondary adrenal insufficiency	✔	-–	✔	✔	-–			Hypopituitarism- Tumors, infections. hemorrhage/trauma Drugs- Chronic steroid therapy and its withdrawal, Opiates Genetic- Combined pituitary hormone deficiency (CPHD), POMC (Proopiomelanocortin) gene deficiency^[1]	-–	Normal
Acute adrenal insufficiency	↓↓	±	✔	✔	✔	±	Signs of shock Altered mental status/ Loss of consciousness/ Coma Fever	Infection Tumor
Differentiating Adrenal Insufficiency from other diseases

↑ Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean L, Bird TD, Ledbetter N, Mefford HC, Smith R, Stephens K, Challis BG, Millington G. PMID 24354022. Vancouver style error: initials (help); Missing or empty |title= (help)

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 ==Adrenal Insufficiency==
 {| class="wikitable"
 !Disease
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 * [[Hypopituitarism]]- Tumors, infections. hemorrhage/trauma
 * Drugs- Chronic [[steroid]] therapy and its withdrawal, [[Opiates]]
-* [[Genetics|Genetic]]- Combined pituitary hormone deficiency (CPHD), [[POMC]] ([[Proopiomelanocortin]]) gene deficiency
+* [[Genetics|Genetic]]- Combined pituitary hormone deficiency (CPHD), [[POMC]] ([[Proopiomelanocortin]]) gene deficiency<ref name="pmid24354022">{{cite journal |vauthors=Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Ledbetter N, Mefford HC, Smith RJH, Stephens K, Challis BG, Millington GWM |title= |journal= |volume= |issue= |pages= |year= |pmid=24354022 |doi= |url=}}</ref>
 |<nowiki>-–</nowiki>
 |Normal