Barrett's esophagus history and symptoms: Difference between revisions

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{{Barrett's esophagus}}
{{Barrett's esophagus}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{AMK}}
==Overview==
==Overview==
The majority of patients with [disease name] are asymptomatic.
The majority of patients with [disease name] are asymptomatic.
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==History==
==History==
* The ususal history is suggestive for GERD clinical manifestations:
* The [[ususal]] [[history]] is [[suggestive]] for [[GERD]] [[clinical manifestations]]:
# Heartburn (pyrosis): burning sensations in the retrosternal area,.<ref name="pmid16928254">{{cite journal |author=Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R |title=The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus |journal=Am. J. Gastroenterol. |volume=101 |issue=8 |pages=1900–20; quiz 1943 |year=2006 |month=August |pmid=16928254 |doi=10.1111/j.1572-0241.2006.00630.x |url=}}</ref>most commpnly after eating.
# [[Heartburn]] [[(pyrosis)]]: [[burning]] [[sensations]] in the [[retrosternal]] [[area]],.<ref name="pmid16928254">{{cite journal |author=Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R |title=The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus |journal=Am. J. Gastroenterol. |volume=101 |issue=8 |pages=1900–20; quiz 1943 |year=2006 |month=August |pmid=16928254 |doi=10.1111/j.1572-0241.2006.00630.x |url=}}</ref>most commpnly after eating.
# Regurgitation: flow of refluxed gastric content into mouth sometimes mixed with undigested food.<ref name="pmid16928254">{{cite journal |author=Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R |title=The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus |journal=Am. J. Gastroenterol. |volume=101 |issue=8 |pages=1900–20; quiz 1943 |year=2006 |month=August |pmid=16928254 |doi=10.1111/j.1572-0241.2006.00630.x |url=}}</ref>
# [[Regurgitation]]: [[flow]] of [[refluxed]] [[gastric]] [[content]] into [[mouth]] [[sometimes]] [[mixed]] [[with]] [[undigested]] [[food]].<ref name="pmid16928254">{{cite journal |author=Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R |title=The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus |journal=Am. J. Gastroenterol. |volume=101 |issue=8 |pages=1900–20; quiz 1943 |year=2006 |month=August |pmid=16928254 |doi=10.1111/j.1572-0241.2006.00630.x |url=}}</ref>
# Dysphagia: potentially suggestive of a stricture.<ref name="pmid15290658">{{cite journal |author=Vakil NB, Traxler B, Levine D |title=Dysphagia in patients with erosive esophagitis: prevalence, severity, and response to proton pump inhibitor treatment |journal=Clin. Gastroenterol. Hepatol. |volume=2 |issue=8 |pages=665–8 |year=2004 |month=August |pmid=15290658 |doi= |url=}}</ref>
# [[Dysphagia]]: [[potentially]] [[suggestive]] of a [[stricture]].<ref name="pmid15290658">{{cite journal |author=Vakil NB, Traxler B, Levine D |title=Dysphagia in patients with erosive esophagitis: prevalence, severity, and response to proton pump inhibitor treatment |journal=Clin. Gastroenterol. Hepatol. |volume=2 |issue=8 |pages=665–8 |year=2004 |month=August |pmid=15290658 |doi= |url=}}</ref>
# Chest pain: mimicking angina pectoris, postprandial, squeezing and burning, substernal, lasting minutes to hours, awakens from sleep, exacerabated by stress, resolves spontaneously or with antiacids.<ref name="pmid8682579">{{cite journal |author=Richter JE |title=Typical and atypical presentations of gastroesophageal reflux disease. The role of esophageal testing in diagnosis and management |journal=Gastroenterol. Clin. North Am. |volume=25 |issue=1 |pages=75–102 |year=1996 |month=March |pmid=8682579 |doi= |url=}}</ref>
# [[Chest pain]]: [[mimicking]] [[angina]] [[pectoris]], [[postprandial]], [[squeezing]] and [[burning]], [[substernal]], [[lasting]] [[minutes]] to [[hours]], [[awakens]] [[from]] [[sleep]], [[exacerabated]] by [[stress]], [[resolves]] [[spontaneously]] or [[with]] [[antiacids]].<ref name="pmid8682579">{{cite journal |author=Richter JE |title=Typical and atypical presentations of gastroesophageal reflux disease. The role of esophageal testing in diagnosis and management |journal=Gastroenterol. Clin. North Am. |volume=25 |issue=1 |pages=75–102 |year=1996 |month=March |pmid=8682579 |doi= |url=}}</ref>
# Globus sensation: sensation of a lump in the throat
# [[Globus]] [[sensation]]: [[sensation]] of a [[lump]] in the [[throat]]
# Odynophagia: if present ususally indicates the presence of an ulcer.
# [[Odynophagia]]: if [[present]] [[ususally]] [[indicates]] [[the]] [[presence]] [[of]] [[an]] [[ulcer]].
# Less commonly: bronchospasms, laryngitis, chronic cough, hypersalivation, nausea.
# [[Less]] [[commonly]]: [[bronchospasms]], [[laryngitis]], [[chronic]] [[cough]], [[hypersalivation]], [[nausea]].


* Patients can also by asymptomatic.
* [[Patients]] [[can]] [[also]] [[by]] [[asymptomatic]].


==Symptoms==
==Symptoms==
Barrett's esophagus itself does not cause symptoms. The acid reflux that causes Barrett's esophagus results in symptoms of [[heartburn]].
[[Barrett's esophagus]] [[itself]] [[does]] [[not]] [[cause]] [[symptoms]]. [[The]] [[acid]] [[reflux]] [[that]] [[causes]] [[Barrett's]] [[esophagus]] [[results]] [[in]] [[symptoms]] [[of]] [[heartburn]].


The change from normal to premalignant cells that indicates Barrett's esophagus does not cause any particular symptoms. However, warning signs that should not be ignored include:
[[The]] [[change]] [[from]] [[normal]] [[to]] [[premalignant]] [[cells]] [[that]] [[indicates]] [[Barrett's esophagus]] [[does]] [[not]] [[cause]] [[any]] [[particular]] [[symptoms]]. [[However]], [[warning]] [[signs]] [[that] [[should]] [[not]] [[be]] [[ignored]] [[include]]:


* Frequent and longstanding [[heartburn]]
* [[Frequent]] [[and]] [[longstanding]] [[heartburn]]
* Trouble swallowing ([[dysphagia]])
* [[Trouble]] [[swallowing]] ([[dysphagia]])
* Vomiting blood
* [[Vomiting]] [[blood]]
* Pain under the breastbone where the esophagus meets the stomach
* [[Pain]] [[under]] [[the]] [[breastbone]] [[where]] [[the]] [[esophagus]] [[meets]] [[the]] [[stomach]]
* Unintentional [[weight loss]] because eating is painful
* [[Unintentional]] [[weight loss]] [[because]] [[eating]] [[is]] [[painful]]


==History and Symptoms==
==History and Symptoms==

Revision as of 13:25, 3 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amresh Kumar MD [2]

Overview

The majority of patients with [disease name] are asymptomatic.

OR

The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].


History

  1. Heartburn (pyrosis): burning sensations in the retrosternal area,.[1]most commpnly after eating.
  2. Regurgitation: flow of refluxed gastric content into mouth sometimes mixed with undigested food.[1]
  3. Dysphagia: potentially suggestive of a stricture.[2]
  4. Chest pain: mimicking angina pectoris, postprandial, squeezing and burning, substernal, lasting minutes to hours, awakens from sleep, exacerabated by stress, resolves spontaneously or with antiacids.[3]
  5. Globus sensation: sensation of a lump in the throat
  6. Odynophagia: if present ususally indicates the presence of an ulcer.
  7. Less commonly: bronchospasms, laryngitis, chronic cough, hypersalivation, nausea.

Symptoms

Barrett's esophagus itself does not cause symptoms. The acid reflux that causes Barrett's esophagus results in symptoms of heartburn.

The change from normal to premalignant cells that indicates Barrett's esophagus does not cause any particular symptoms. However, warning signs [[that] should not be ignored include:

History and Symptoms

  • The majority of patients with [disease name] are asymptomatic.

OR

  • The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
  • Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 

History

Patients with [disease name]] may have a positive history of:

  • [History finding 1]
  • [History finding 2]
  • [History finding 3]

Common Symptoms

Common symptoms of [disease] include:

  • [Symptom 1]
  • [Symptom 2]
  • [Symptom 3]

Less Common Symptoms

Less common symptoms of [disease name] include

  • [Symptom 1]
  • [Symptom 2]
  • [Symptom 3]

References

  1. ↑ 1.0 1.1 Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R (2006). "The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus". Am. J. Gastroenterol. 101 (8): 1900–20, quiz 1943. doi:10.1111/j.1572-0241.2006.00630.x. PMID 16928254. Unknown parameter |month= ignored (help)
  2. ↑ Vakil NB, Traxler B, Levine D (2004). "Dysphagia in patients with erosive esophagitis: prevalence, severity, and response to proton pump inhibitor treatment". Clin. Gastroenterol. Hepatol. 2 (8): 665–8. PMID 15290658. Unknown parameter |month= ignored (help)
  3. ↑ Richter JE (1996). "Typical and atypical presentations of gastroesophageal reflux disease. The role of esophageal testing in diagnosis and management". Gastroenterol. Clin. North Am. 25 (1): 75–102. PMID 8682579. Unknown parameter |month= ignored (help)

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