Irritable bowel syndrome pathophysiology: Difference between revisions

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Revision as of 14:54, 20 October 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The exact pathogenesis of [disease name] is not fully understood.

OR

It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].

OR

[Pathogen name] is usually transmitted via the [transmission route] route to the human host.

OR

Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.

OR

[Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].

OR

The progression to [disease name] usually involves the [molecular pathway].

OR

The pathophysiology of [disease/malignancy] depends on the histological subtype.

Pathophysiology

Pathogenesis

The exact pathogenesis of [disease name] is not fully understood.

OR

It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
[Pathogen name] is usually transmitted via the [transmission route] route to the human host.
Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
[Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
The progression to [disease name] usually involves the [molecular pathway].
The pathophysiology of [disease/malignancy] depends on the histological subtype.

Genetics

[Disease name] is transmitted in [mode of genetic transmission] pattern.
Genes involved in the pathogenesis of [disease name] include [gene1], [gene2], and [gene3].
The development of [disease name] is the result of multiple genetic mutations.

Associated Conditions

Gross Pathology

On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

Microscopic Pathology

On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

References

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@@ Line 1: / Line 1: @@
 __NOTOC__
-{{Irritable bowel syndrome}}
+{{Xyz}}
 {{CMG}}; {{AE}}
 ==Overview==
+The exact pathogenesis of [disease name] is not fully understood.
+OR
+It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
+OR
+[Pathogen name] is usually transmitted via the [transmission route] route to the human host.
+OR
+Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
+OR
+[Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
+OR
+The progression to [disease name] usually involves the [molecular pathway].
+OR
+The pathophysiology of [disease/malignancy] depends on the histological subtype.
 ==Pathophysiology==
-*IBS is a functional disorder of visceral hypersensitivity which may lead to abdominal discomfort, diarrhea and constipation. <ref name="pmid12454866">{{cite journal |vauthors=Drossman DA, Camilleri M, Mayer EA, Whitehead WE |title=AGA technical review on irritable bowel syndrome |journal=Gastroenterology |volume=123 |issue=6 |pages=2108–31 |year=2002 |pmid=12454866 |doi=10.1053/gast.2002.37095 |url=}}</ref> <ref name="pmid12241674">{{cite journal |vauthors=Talley NJ, Spiller R |title=Irritable bowel syndrome: a little understood organic bowel disease? |journal=Lancet |volume=360 |issue=9332 |pages=555–64 |year=2002 |pmid=12241674 |doi=10.1016/S0140-6736(02)09712-X |url=}}</ref> <ref name="pmid24944467">{{cite journal |vauthors=Saha L |title=Irritable bowel syndrome: pathogenesis, diagnosis, treatment, and evidence-based medicine |journal=World J. Gastroenterol. |volume=20 |issue=22 |pages=6759–73 |year=2014 |pmid=24944467 |pmc=4051916 |doi=10.3748/wjg.v20.i22.6759 |url=}}</ref>
-*The pathophysiology of IBS is uncertain. It has been postulated that this may be secondary to psychological causes.
+===Pathogenesis===
+*The exact pathogenesis of [disease name] is not fully understood.
+OR
+*It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
+*[Pathogen name] is usually transmitted via the [transmission route] route to the human host.
+*Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
+*[Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].
+*The progression to [disease name] usually involves the [molecular pathway].
+*The pathophysiology of [disease/malignancy] depends on the histological subtype.
 ==Genetics==
 *[Disease name] is transmitted in [mode of genetic transmission] pattern.