Acute promyelocytic leukemia history and symptoms: Difference between revisions
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{{Acute promyelocytic leukemia}} | {{Acute promyelocytic leukemia}} | ||
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==Overview== | ==Overview== | ||
Signs and symptoms of acute promyelocytic leukemia are similar to other forms of | Signs and symptoms of acute promyelocytic leukemia are similar to other forms of leukemia, but bleeding and hemorrhagic events are more specific for acute promyelocytic leukemia since these patients are more likely to present with [[disseminated intravascular coagulation]] (coagulopathy). | ||
==Symptoms== | ==Symptoms== | ||
Symptoms include | Symptoms include | ||
*[[Fever]] | *[[Fever]] | ||
*[[fatigue (physical)|Fatigue]] | *[[fatigue (physical)|Fatigue]] | ||
*[[Weight loss]] | *[[Weight loss]] | ||
*Loss of appetite | |||
*Shortness of breath with exertion | *Shortness of breath with exertion | ||
*[[Anemia]] | *[[Anemia]] | ||
*Easy bruising | *Easy bruising from thrombocytopenia and [[coagulopathy]] | ||
*Mucosal bleeding from thrombocytopenia and [[coagulopathy]] | |||
*[[Petechiae]] (flat, pin-head sized spots under the skin caused by [[bleeding]]) | *[[Petechiae]] (flat, pin-head sized spots under the skin caused by [[bleeding]]) | ||
*Bone and joint pain | *Bone and joint pain | ||
Revision as of 01:31, 7 May 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]
Overview
Signs and symptoms of acute promyelocytic leukemia are similar to other forms of leukemia, but bleeding and hemorrhagic events are more specific for acute promyelocytic leukemia since these patients are more likely to present with disseminated intravascular coagulation (coagulopathy).
Symptoms
Symptoms include
- Fever
- Fatigue
- Weight loss
- Loss of appetite
- Shortness of breath with exertion
- Anemia
- Easy bruising from thrombocytopenia and coagulopathy
- Mucosal bleeding from thrombocytopenia and coagulopathy
- Petechiae (flat, pin-head sized spots under the skin caused by bleeding)
- Bone and joint pain
- Persistent or frequent infections (from lack of normal white blood cells)