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| {{CMG}}; {{AE}} {{MKK}} | | {{CMG}}; {{AE}} {{MKK}} |
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| ==Overview==
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| * The overview section should include the disease name in the first sentence.
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| * The goal is to summarize the entire page in several sentences. This section can be the same as the natural history, complications and prognosis segment on the overview page.
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| * To see an example, click [[Pericarditis natural history#Overview|here]].
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| ===Template===
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| *'''First Sentences:'''
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| :If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3]. Common complications of [disease name] include [complication 1], [complication 2], and [complication 3]. Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
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| :OR
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| :Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
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| *'''Examples:'''
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| :Example 1: If left untreated, 20% to 30% of patients with IgA nephropathy may progress to develop ESRD. Common complications of IgA nephropathy include pro-thrombotic states, such as stroke and myocardial infarction. Prognosis is generally good, and the 5-year mortality rate of patients with IgA nephropathy is approximately 5%.
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| *'''Additional Sentences:'''
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| :[Disease/malignancy] is associated with a 5 year survival rate of [#]%.
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| :The presence of metastasis is associated with a particularly poor prognosis among patients with [disease/malignancy]. The 5 year event free survival rate is less than [#]%.
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| :The [Subtype of disease or malignancy] is associated with the most favorable prognosis.
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| :The prognosis varies with the [characteristic] of tumor: [subtype of disease/malignancy] have the most favorable prognosis.
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| *'''Examples:'''
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| :Example 1: Rhabdomyosarcoma is associated with a 5 year survival rate of 72%.
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| :Example 2: The presence of metastasis is associated with a particularly poor prognosis among patients with rhabdomyosarcoma. The 5 year event free survival rate is less than 30%.
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| :Example 3: The embryonal subtype of rhabdomyosarcoma is associated with the most favorable prognosis.
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| :Example 4: The prognosis varies with the location of tumor: orbital and genitourinary tract rhabdomyosarcomas have the most favorable prognosis.
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| ==Preferred Template Statements==
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| *If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
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| *Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
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| *Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
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| *Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
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| ===Additional Sentences===
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| *The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
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| *[Subtype of disease/malignancy] is associated with the most favorable prognosis.
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| *The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
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| ==Natural History==
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| *The Helicobacter pylori is acquired usually during the childhood of life mainly those who have low socioeconomic status, increased number of siblings and similar infection in the mother<ref name="pmid11045838">{{cite journal |vauthors=Opekun AR, Gilger MA, Denyes SM, Nirken MH, Philip SP, Osato MS, Malaty HM, Hicks J, Graham DY |title=Helicobacter pylori infection in children of Texas |journal=J. Pediatr. Gastroenterol. Nutr. |volume=31 |issue=4 |pages=405–10 |year=2000 |pmid=11045838 |doi= |url=}}</ref><ref name="pmid11063492">{{cite journal |vauthors=Parkinson AJ, Gold BD, Bulkow L, Wainwright RB, Swaminathan B, Khanna B, Petersen KM, Fitzgerald MA |title=High prevalence of Helicobacter pylori in the Alaska native population and association with low serum ferritin levels in young adults |journal=Clin. Diagn. Lab. Immunol. |volume=7 |issue=6 |pages=885–8 |year=2000 |pmid=11063492 |pmc=95979 |doi= |url=}}</ref><ref name="pmid11918912">{{cite journal |vauthors=Malaty HM, El-Kasabany A, Graham DY, Miller CC, Reddy SG, Srinivasan SR, Yamaoka Y, Berenson GS |title=Age at acquisition of Helicobacter pylori infection: a follow-up study from infancy to adulthood |journal=Lancet |volume=359 |issue=9310 |pages=931–5 |year=2002 |pmid=11918912 |doi=10.1016/S0140-6736(02)08025-X |url=}}</ref>The duodenal ulcer occurs in 20-50 years of age.The gastric ulcer occurs in the age above 40 years . It start with symptoms such as episodic epigastric pain, indigestion,oating.Without treatment, the patient will develop symptoms of perforation, which may eventually lead to acute circulatory failure....<ref name="pmid16847081">{{cite journal |vauthors=Kusters JG, van Vliet AH, Kuipers EJ |title=Pathogenesis of Helicobacter pylori infection |journal=Clin. Microbiol. Rev. |volume=19 |issue=3 |pages=449–90 |year=2006 |pmid=16847081 |pmc=1539101 |doi=10.1128/CMR.00054-05 |url=}}</ref>
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| ==Complications==
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| Acute and common complications :
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| *Bleeding
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| *Perforation
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| *Peritonitis
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| *Obstruction
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| *Stricture
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| Chronic and rare complications:
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| *Gastric cancer-Chronic Helicobacter pylori leads to
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| *MALT cell lymphoma
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| *Iron deficiency anemia
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| *Idiopathic thrombocytopenic purpuras
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| *Signs of bleeding:
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| **Melena -blood in stools
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| **Hematemesis-blood in vomitus
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| **Anemia-pale colored skin, shortness of breath during physical activity, tachycardia
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| * For an example of the complications section in a natural history, complications and prognosis page, click [[Pericarditis natural history#complications|here]].
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| ==Prognosis==
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| * This section should detail the prognosis of the disease, both treated and untreated.
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| * Here are some template sentences; "The prognosis of (disease name) is poor/good with treatment. Without treatment, (disease name) will result in ___. (Disease name) is associated with a 1/5/10 year mortality of __ among patient with ______ (for example high grade lesions). The presence of ___ is associated with a particularly poor prognosis among patients with (disease name).
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| * For an example of a prognosis section within a natural history, complications and prognosis page, click [[Pericarditis natural history#prognosis|here]].
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| ==References== | | ==References== |