Peptic ulcer historical perspective: Difference between revisions
No edit summary |
|||
| Line 15: | Line 15: | ||
In 2005, the Karolinska Institute in Stockholm awarded the [[Nobel Prize in Physiology or Medicine]] to Dr. Marshall and his long-time collaborator Dr. [[Robin Warren|Warren]] "for their discovery of the bacterium ''Helicobacter pylori'' and its role in [[gastritis]] and peptic ulcer disease". Professor Marshall continues research related to ''H. pylori'' and runs a molecular biology lab at UWA in Perth, Western Australia. | In 2005, the Karolinska Institute in Stockholm awarded the [[Nobel Prize in Physiology or Medicine]] to Dr. Marshall and his long-time collaborator Dr. [[Robin Warren|Warren]] "for their discovery of the bacterium ''Helicobacter pylori'' and its role in [[gastritis]] and peptic ulcer disease". Professor Marshall continues research related to ''H. pylori'' and runs a molecular biology lab at UWA in Perth, Western Australia. | ||
Gastric ulcer was first discovered by Goldstein, a [nationality + occupation], in [year]/during/following [event]. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 14:49, 26 October 2017
|
Peptic ulcer Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Surgery |
|
Case Studies |
|
2017 ACG Guidelines for Peptic Ulcer Disease |
|
Guidelines for the Indications to Test for, and to Treat, H. pylori Infection |
|
Guidlines for factors that predict the successful eradication when treating H. pylori infection |
|
Guidelines to document H. pylori antimicrobial resistance in the North America |
|
Guidelines for evaluation and testing of H. pylori antibiotic resistance |
|
Guidelines for when to test for treatment success after H. pylori eradication therapy |
|
Guidelines for penicillin allergy in patients with H. pylori infection |
|
Peptic ulcer historical perspective On the Web |
|
American Roentgen Ray Society Images of Peptic ulcer historical perspective |
|
Risk calculators and risk factors for Peptic ulcer historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ;Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
Historical Perspective
In 1997, the Centers for Disease Control and Prevention, with other government agencies, academic institutions, and industry, launched a national education campaign to inform health care providers and consumers about the link between H. pylori and ulcers. This campaign reinforced the news that ulcers are a curable infection, and the fact that health can be greatly improved and money saved by disseminating information about H. pylori.[1]
Helicobacter pylori was rediscovered in 1982 by two Australian scientists Robin Warren and Barry Marshall[2]. In their original paper, Warren and Marshall contended that most stomach ulcers and gastritis were caused by colonization with this bacterium, not by stress or spicy food as had been assumed before.[3]
The H. pylori hypothesis was poorly received, so in an act of self-experimentation Marshall drank a petri-dish containing a culture of organisms extracted from a patient and soon developed gastritis. His symptoms disappeared after two weeks, but he took antibiotics to kill the remaining bacteria at the urging of his wife, since halitosis is one of the symptoms of infection.[4] This experiment was published in 1984 in the Australian Medical Journal and is among the most cited articles from the journal.
In 2005, the Karolinska Institute in Stockholm awarded the Nobel Prize in Physiology or Medicine to Dr. Marshall and his long-time collaborator Dr. Warren "for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease". Professor Marshall continues research related to H. pylori and runs a molecular biology lab at UWA in Perth, Western Australia. Gastric ulcer was first discovered by Goldstein, a [nationality + occupation], in [year]/during/following [event].
References
- ↑ Ulcer, Diagnosis and Treatment - CDC Bacterial, Mycotic Diseases
- ↑ Marshall BJ (1983). "Unidentified curved bacillus on gastric epithelium in active chronic gastritis". Lancet. 1 (8336): 1273–1275. PMID 6134060.
- ↑ Marshall BJ, Warren JR (1984). "Unidentified curved bacilli in the stomach patients with gastritis and peptic ulceration". Lancet. 1 (8390): 1311–1315. PMID 6145023.
- ↑ "Research Enterprise, The 2005 Nobel Prize in Physiology or Medicine". Retrieved 2007-08-26.