Plummer-Vinson syndrome causes: Difference between revisions
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* [[Growth]] | * [[Growth]] | ||
* [[Pregnancy]] | * [[Pregnancy]] | ||
* Frequent blood donation | |||
====Pathological==== | ====Pathological==== | ||
=====Blood Loss===== | =====Blood Loss===== | ||
* | * Menstruation | ||
* Gastrointestinal tract (bleeding from the [[gastrointestinal tract]] ([[ulcers]], [[hemorrhoid]]s, [[Esophageal varices]], The use of [[aspirin]], [[ibuprofen]], or [[Arthritis (patient information)|arthritis]] medicines for a long time, Cancer in the esophagus, stomach, or colon) | * Gastrointestinal tract (bleeding from the [[gastrointestinal tract]] ([[ulcers]], [[hemorrhoid]]s, [[Esophageal varices]], The use of [[aspirin]], [[ibuprofen]], or [[Arthritis (patient information)|arthritis]] medicines for a long time, Cancer in the esophagus, stomach, or colon) | ||
** Food sensitivity | ** Food sensitivity | ||
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* [[Genitourinary tract]] | * [[Genitourinary tract]] | ||
* [[Respiratory tract]] (Rarely [[laryngological]] bleeding or from the [[respiratory tract]]) | * [[Respiratory tract]] (Rarely [[laryngological]] bleeding or from the [[respiratory tract]]) | ||
* Hemoptysis (alveolar hemorrhage) | |||
* Blood donation | * Blood donation | ||
* Nosocomial blood loss: phlebotomy for diagnostic tests in hospitalized patients | |||
* Following gastric or small bowel surgery: due to loss of gastric acidity, increased transit time for food, and decreased absorption of iron | |||
===Inadequate Iron Absorption=== | ===Inadequate Iron Absorption=== | ||
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Kwashiorkor disease | Kwashiorkor disease | ||
Alcoholism | Alcoholism | ||
Less common causes | |||
Hereditary hemorrhagic telangiectasia: recurrent hemorrhage | |||
Intravascular hemolysis: for example, paroxysmal nocturnal hemoglobinuria. | |||
Iatrogenic causes such as frequent blood draws, particularly in hospitalized patients | |||
inadequate diet in children (excessive consumption of whole cow's milk) | |||
==References== | ==References== | ||
Revision as of 15:21, 1 November 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Causes
The cause of Plummer-Vinson syndrome is unknown; however, iron deficiency anemia, genetic factors and nutritional deficiencies may play a role. Iron deficiency anemia can be due to:
Increased Iron Requirement
Physiological
Pathological
Blood Loss
- Menstruation
- Gastrointestinal tract (bleeding from the gastrointestinal tract (ulcers, hemorrhoids, Esophageal varices, The use of aspirin, ibuprofen, or arthritis medicines for a long time, Cancer in the esophagus, stomach, or colon)
- Food sensitivity
- Hookworms
- Genitourinary tract
- Respiratory tract (Rarely laryngological bleeding or from the respiratory tract)
- Hemoptysis (alveolar hemorrhage)
- Blood donation
- Nosocomial blood loss: phlebotomy for diagnostic tests in hospitalized patients
- Following gastric or small bowel surgery: due to loss of gastric acidity, increased transit time for food, and decreased absorption of iron
Inadequate Iron Absorption
- Dietary deficiency
- Impaired absorption (Celiac disease, Crohn's disease)
- Intestinal malabsorption
- Gastric surgery
- Hypochorhydria
- Taking too many antacids that contain calcium
celiac disease
tropical sprue
Crohn’s disease
Whipple disease
Kwashiorkor disease
Alcoholism
Less common causes
Hereditary hemorrhagic telangiectasia: recurrent hemorrhage
Intravascular hemolysis: for example, paroxysmal nocturnal hemoglobinuria.
Iatrogenic causes such as frequent blood draws, particularly in hospitalized patients
inadequate diet in children (excessive consumption of whole cow's milk)