Plummer-Vinson syndrome causes: Difference between revisions
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{{Plummer-Vinson syndrome}} | {{Plummer-Vinson syndrome}} | ||
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==Overview== | ==Overview== | ||
==Causes== | ==Causes== | ||
The cause of Plummer-Vinson syndrome is unknown; however, iron deficiency anemia, [[Genetics|genetic]] factors and [[nutrition|nutritional deficiencies]] may play a role. Iron deficiency anemia can be due to: | The cause of Plummer-Vinson syndrome is unknown; however, iron deficiency anemia, [[Genetics|genetic]] factors and [[nutrition|nutritional deficiencies]] may play a role. Iron deficiency anemia is the most widely regarded cause of Plummer-Vinson syndrome and can be due to: | ||
===Increased Iron Requirement=== | ===Increased Iron Requirement=== | ||
Revision as of 14:20, 3 November 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]
Overview
Causes
The cause of Plummer-Vinson syndrome is unknown; however, iron deficiency anemia, genetic factors and nutritional deficiencies may play a role. Iron deficiency anemia is the most widely regarded cause of Plummer-Vinson syndrome and can be due to:
Increased Iron Requirement
Physiological
Pathological
Blood Loss
- Menstruation
- Gastrointestinal tract (bleeding from the gastrointestinal tract (ulcers, hemorrhoids, Esophageal varices, The use of aspirin, ibuprofen, or arthritis medicines for a long time, Cancer in the esophagus, stomach, or colon)
- Food sensitivity
- Hookworms
- Genitourinary tract
- Respiratory tract (Rarely laryngological bleeding or from the respiratory tract)
- Hemoptysis (alveolar hemorrhage)
- Blood donation
- Nosocomial blood loss: phlebotomy for diagnostic tests in hospitalized patients
- Following gastric or small bowel surgery: due to loss of gastric acidity, increased transit time for food, and decreased absorption of iron
Inadequate Iron Absorption
- Dietary deficiency
- Impaired absorption (Celiac disease, Crohn's disease)
- Intestinal malabsorption
- Gastric surgery
- Hypochorhydria
- Taking too many antacids that contain calcium
celiac disease
tropical sprue
Crohn’s disease
Whipple disease
Kwashiorkor disease
Alcoholism
Less common causes
Hereditary hemorrhagic telangiectasia: recurrent hemorrhage
Intravascular hemolysis: for example, paroxysmal nocturnal hemoglobinuria.
Iatrogenic causes such as frequent blood draws, particularly in hospitalized patients
inadequate diet in children (excessive consumption of whole cow's milk)