Sandbox: Cardiogenic Shock: Difference between revisions

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{| class="wikitable" style="width: 90%; text-align: justify;"  
{| class="wikitable" style="width: 90%; text-align: justify;"  


! style="width:10%" | '''Clinical Definition'''
! style="width:20%" | '''Clinical Definition'''
! style="width:30%" | '''SHOCK Trial'''
! style="width:25%" | '''SHOCK Trial'''
! style="width:60%" | '''IABP-SHOCK II'''
! style="width:25%" | '''IABP-SHOCK II'''
! style="width:60%" | '''ESC HF Guidelines'''
! style="width:30%" | '''ESC HF Guidelines'''
|-  
|-  
| Cardiac disorder that results in both clinical and biochemical evidence of tissue hypoperfusion || Clinical criteria:
| Cardiac disorder that results in both clinical and biochemical evidence of tissue hypoperfusion  
|| Clinical criteria:
SBP <90 mmHg for ≥30 min OR Support to maintain SBP ≥90 mmHg AND
SBP <90 mmHg for ≥30 min OR Support to maintain SBP ≥90 mmHg AND
End-organ hypoperfusion (urine output <30 mL/h or cool extremities)
End-organ hypoperfusion (urine output <30 mL/h or cool extremities)
Hemodynamic criteria:
Hemodynamic criteria:
CI of ≤2.2 L·min−1·m−2 AND PCWP ≥15 mmHg || Clinical criteria:
CI of ≤2.2 L·min−1·m−2 AND PCWP ≥15 mmHg  
|| Clinical criteria:
SBP <90 mmHg for ≥30 min OR Catecholamines to maintain SBP >90 mmHg AND
SBP <90 mmHg for ≥30 min OR Catecholamines to maintain SBP >90 mmHg AND
Clinical pulmonary congestion
Clinical pulmonary congestion
AND
AND
Impaired end-organ perfusion (altered mental status, cold/clammy skin and extremities, urine output <30 mL/h, or lactate >2.0 mmol/L) || SBP <90 mmHg with adequate volume and clinical or laboratory signs of hypoperfusion
Impaired end-organ perfusion (altered mental status, cold/clammy skin and extremities, urine output <30 mL/h, or lactate >2.0 mmol/L)  
|| SBP <90 mmHg with adequate volume and clinical or laboratory signs of hypoperfusion
Clinical hypoperfusion:
Clinical hypoperfusion:
Cold extremities, oliguria, mental confusion, dizziness, narrow pulse pressure
Cold extremities, oliguria, mental confusion, dizziness, narrow pulse pressure
Laboratory hypoperfusion:
Laboratory hypoperfusion:
Metabolic acidosis, elevated serum lactate, elevated serum creatinine
Metabolic acidosis, elevated serum lactate, elevated serum creatinine
|-
| CI indicates cardiac index; CS, cardiogenic shock; ESC, European Society of Cardiology; HF, heart failure; IABP-SHOCK II, Intraaortic Balloon Pump in Cardiogenic Shock II; LV, left ventricular; MI, myocardial infarction; PCWP, pulmonary capillary wedge pressure; SBP, systolic blood pressure; and SHOCK, Should We Emergently Revascularize Occluded Coronaries for Cariogenic Shock || || ||
|}
|}

Revision as of 13:24, 3 November 2017


Template:Cardiogenic Shock - 2017 Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Associate Editor(s)-in-Chief: Arzu Kalayci, M.D. [2]

Contemporary Management of Cardiogenic Shock

Pragmatic and Clinical Trial De nitions of Cardiogenic Shock

Clinical Definition SHOCK Trial IABP-SHOCK II ESC HF Guidelines
Cardiac disorder that results in both clinical and biochemical evidence of tissue hypoperfusion Clinical criteria:

SBP <90 mmHg for ≥30 min OR Support to maintain SBP ≥90 mmHg AND End-organ hypoperfusion (urine output <30 mL/h or cool extremities) Hemodynamic criteria: CI of ≤2.2 L·min−1·m−2 AND PCWP ≥15 mmHg

Clinical criteria:

SBP <90 mmHg for ≥30 min OR Catecholamines to maintain SBP >90 mmHg AND Clinical pulmonary congestion AND Impaired end-organ perfusion (altered mental status, cold/clammy skin and extremities, urine output <30 mL/h, or lactate >2.0 mmol/L)

SBP <90 mmHg with adequate volume and clinical or laboratory signs of hypoperfusion

Clinical hypoperfusion: Cold extremities, oliguria, mental confusion, dizziness, narrow pulse pressure Laboratory hypoperfusion: Metabolic acidosis, elevated serum lactate, elevated serum creatinine

CI indicates cardiac index; CS, cardiogenic shock; ESC, European Society of Cardiology; HF, heart failure; IABP-SHOCK II, Intraaortic Balloon Pump in Cardiogenic Shock II; LV, left ventricular; MI, myocardial infarction; PCWP, pulmonary capillary wedge pressure; SBP, systolic blood pressure; and SHOCK, Should We Emergently Revascularize Occluded Coronaries for Cariogenic Shock