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CI of ≤2.2 L·min−1·m−2 AND PCWP ≥15 mmHg  
CI of ≤2.2 L·min−1·m−2 AND PCWP ≥15 mmHg  
|| Clinical criteria:
|| Clinical criteria:
SBP <90 mmHg for ≥30 min OR Catecholamines to maintain SBP >90 mmHg AND
SBP <90 mmHg for ≥30 min OR Catecholamines to maintain SBP >90 mmHg AND  
Clinical pulmonary congestion
 
AND
Clinical pulmonary congestion  
 
AND  
 
Impaired end-organ perfusion (altered mental status, cold/clammy skin and extremities, urine output <30 mL/h, or lactate >2.0 mmol/L)  
Impaired end-organ perfusion (altered mental status, cold/clammy skin and extremities, urine output <30 mL/h, or lactate >2.0 mmol/L)  
|| SBP <90 mmHg with adequate volume and clinical or laboratory signs of hypoperfusion
|| SBP <90 mmHg with adequate volume and clinical or laboratory signs of hypoperfusion
Clinical hypoperfusion:
Clinical hypoperfusion:
Cold extremities, oliguria, mental confusion, dizziness, narrow pulse pressure
Cold extremities, oliguria, mental confusion, dizziness, narrow pulse pressure
Laboratory hypoperfusion:
Laboratory hypoperfusion:
Metabolic acidosis, elevated serum lactate, elevated serum creatinine
Metabolic acidosis, elevated serum lactate, elevated serum creatinine
|-  
|-  
| colspan="4" | '''CI''' indicates cardiac index; '''CS''', cardiogenic shock; '''ESC''', European Society of Cardiology; HF, heart failure; '''IABP-SHOCK II''', Intraaortic Balloon Pump in Cardiogenic Shock II; '''LV''', left ventricular; '''MI''', myocardial infarction; '''PCWP''', pulmonary capillary wedge pressure; '''SBP''', systolic blood pressure; and '''SHOCK''', Should We Emergently Revascularize Occluded Coronaries for Cariogenic Shock  
| colspan="4" | '''CI''' indicates cardiac index; '''CS''', cardiogenic shock; '''ESC''', European Society of Cardiology; HF, heart failure; '''IABP-SHOCK II''', Intraaortic Balloon Pump in Cardiogenic Shock II; '''LV''', left ventricular; '''MI''', myocardial infarction; '''PCWP''', pulmonary capillary wedge pressure; '''SBP''', systolic blood pressure; and '''SHOCK''', Should We Emergently Revascularize Occluded Coronaries for Cariogenic Shock  
|}
|}

Revision as of 13:28, 3 November 2017


Template:Cardiogenic Shock - 2017 Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Associate Editor(s)-in-Chief: Arzu Kalayci, M.D. [2]

Contemporary Management of Cardiogenic Shock

Pragmatic and Clinical Trial Definitions of Cardiogenic Shock

Clinical Definition SHOCK Trial IABP-SHOCK II ESC HF Guidelines
Cardiac disorder that results in both clinical and biochemical evidence of tissue hypoperfusion Clinical criteria:

SBP <90 mmHg for ≥30 min OR

Support to maintain SBP ≥90 mmHg AND

End-organ hypoperfusion (urine output <30 mL/h or cool extremities)

Hemodynamic criteria:

CI of ≤2.2 L·min−1·m−2 AND PCWP ≥15 mmHg

Clinical criteria:

SBP <90 mmHg for ≥30 min OR Catecholamines to maintain SBP >90 mmHg AND

Clinical pulmonary congestion

AND

Impaired end-organ perfusion (altered mental status, cold/clammy skin and extremities, urine output <30 mL/h, or lactate >2.0 mmol/L)

SBP <90 mmHg with adequate volume and clinical or laboratory signs of hypoperfusion

Clinical hypoperfusion:

Cold extremities, oliguria, mental confusion, dizziness, narrow pulse pressure Laboratory hypoperfusion:

Metabolic acidosis, elevated serum lactate, elevated serum creatinine

CI indicates cardiac index; CS, cardiogenic shock; ESC, European Society of Cardiology; HF, heart failure; IABP-SHOCK II, Intraaortic Balloon Pump in Cardiogenic Shock II; LV, left ventricular; MI, myocardial infarction; PCWP, pulmonary capillary wedge pressure; SBP, systolic blood pressure; and SHOCK, Should We Emergently Revascularize Occluded Coronaries for Cariogenic Shock