Carcinoid syndrome causes: Difference between revisions

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Revision as of 01:04, 3 January 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Common causes of carcinoid syndrome include genetic disorders (multiple endocrine neoplasia type 1 and neurofibromatosis type 1) and genetic mutations (gains involving chromosomes 5, 14, 17, and 19 and losses involving chromosomes 11 and 18).^[1]

Common causes of carcinoid syndrome includes:^[1]


Genetic Disorder	Tumor Location

Multiple endocrine neoplasia type 1	Carcinoids associated with multiple endocrine neoplasia type 1 appear to be of foregut origin
Neurofibromatosis type 1	Carcinoids in patients with neurofibromatosis type 1 appear to arise primarily in the periampullary region


Type of Mutation	Chromosomes

Gains	Chromosome 5 Chromosome 14 Chromosome 17 Chromosome 19
Losses	Chromosome 1 Chromosome 18

@@ Line 7: / Line 7: @@
 ==Causes==
-Common causes of carcinoid syndrome include:<ref name=aaa>Molecular genetics. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-treatment-pdq</ref>
+Common causes of carcinoid syndrome includes:<ref name=aaa>Molecular genetics. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-treatment-pdq</ref>
 *'''Genetic disorders'''
@@ Line 47: / Line 47: @@
 Losses
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Chromosome 11
+*Chromosome 1
 *Chromosome 18
 |}