Whipple's disease classification: Difference between revisions
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**Localized involvement of different organs including: | **Localized involvement of different organs including: | ||
***[[Heart]]: | ***[[Heart]]: | ||
****Blood-culture negative endocarditis | ****Blood-culture negative [[endocarditis]] | ||
****Adhesive pericarditis | ****Adhesive [[pericarditis]] | ||
****Myocardial fibrosis | ****[[Myocardial]] [[fibrosis]] | ||
***[[CNS]]: | ***[[CNS]]: | ||
****Encephalitis | ****[[Encephalitis]] | ||
****Progressive dementia | ****Progressive [[dementia]] | ||
****Cerebellar ataxia | ****[[Cerebellar ataxia]] | ||
****Personality changes | ****[[Personality changes]] | ||
****Hemiparesis | ****[[Hemiparesis]] | ||
****Seizure | ****[[Seizure]] | ||
****Wernicke’s encephalopathy | ****[[Wernicke's Encephalopathy|Wernicke’s encephalopathy]] | ||
****Hypothalamic involvement | ****[[Hypothalamic]] involvement | ||
****Supranuclear ophthalmoplegia | ****[[Supranuclear ophthalmoplegia]] | ||
***[[Eyes]]: | ***[[Eyes]]: | ||
****[[Uveitis]] | |||
****Vitritis | |||
****[[Retinitis]] | |||
****[[Retrobulbar neuritis]] | |||
****[[Papilledema]] | |||
***[[Lung]]: | ***[[Lung]]: | ||
****Chronic [[cough]] | |||
****[[Dyspnea]] | |||
***[[Bone]]: | ***[[Bone]]: | ||
****[[Arthritis]] | |||
****[[Spondylodiscitis]] | |||
***[[Serosa]]: | ***[[Serosa]]: | ||
****[[Pleuritic chest pain]] | |||
***[[Skin]]: | ***[[Skin]]: | ||
****[[Hyperpigmentation]] | |||
<br> | <br> | ||
'''Whipple's disease classification based on the duration''' | '''Whipple's disease classification based on the duration''' | ||
Revision as of 01:19, 7 November 2017
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Whipple's disease Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Whipple's disease classification On the Web |
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American Roentgen Ray Society Images of Whipple's disease classification |
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Risk calculators and risk factors for Whipple's disease classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]
Overview
Whipple’s disease may be classified into 4 groups based on clinical manifestation: Acute infection, asymptomatic carrier state, the classic Whipple’s disease, and localized chronic infection.
Classification
- Whipple's disease may be classified to 2 groups of acute and chronic based on the duration.
- Whipple's disease may be classified to 2 groups of systemic and localized infection based on organ involvement.
- Tropheryma whipplei infection may be classified to 4 groups based on the clinical manifestation:[1][2]
- Acute infections such as:
- Asymptomatic carrier state
- The classic Whipple’s disease
- Localized involvement of different organs including:
- Heart:
- Blood-culture negative endocarditis
- Adhesive pericarditis
- Myocardial fibrosis
- CNS:
- Eyes:
- Uveitis
- Vitritis
- Retinitis
- Retrobulbar neuritis
- Papilledema
- Lung:
- Bone:
- Serosa:
- Skin:
- Heart:
Whipple's disease classification based on the duration
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Whipple's disease classification based on organ involvement
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References
- ↑ Marth, Thomas (2009). "New Insights into Whipple's Disease – A Rare Intestinal Inflammatory Disorder". Digestive Diseases. 27 (4): 494–501. doi:10.1159/000233288. ISSN 1421-9875.
- ↑ Street, Sara; Donoghue, Helen D; Neild, GH (1999). "Tropheryma whippelii DNA in saliva of healthy people". The Lancet. 354 (9185): 1178–1179. doi:10.1016/S0140-6736(99)03065-2. ISSN 0140-6736.