Barrett's esophagus secondary prevention: Difference between revisions

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Recommendations:
Recommendations:


* [[Therapy]] [[with]] [[medications]] [[effective]] [[to]] [[treat]] [[GERD]] [[symptoms]] [[and]] [[to]] [[heal]] [[reflux esophagitis]] [[is]] [[strongly]] [[recommended]].
* [[Therapy]] with [[medications]] effective to treat [[GERD]] [[symptoms]] and to heal [[reflux esophagitis]] is strongly recommended.


* [[Do]] [[not]] [[attempt]] [[to]] [[eliminate]] [[acid]] [[exposure]] [[of]] [[the]] [[esophagus]]
* Do not attempt to eliminate [[acid]] exposure of the [[esophagus]]
# [[Use]] [[proton pump inhibitors]] [[in]] [[doses]] [[greater]] [[than]] [[once]] [[daily]]. [[There]] [[is]] [[no]] [[evidence]] [[that]] [[higher]] [[doses]] [[produce]] [[a]] [[risk]] [[reduction]] [[in]] [[cancer]].
# Use [[proton pump inhibitors]] in [[doses]] greater than once daily. There is no [[evidence]] that higher [[doses]] produce a risk [[reduction]] in [[cancer]].
# [[Titrate]] [[proton pump inhibitors]] [[dose]] [[by]] [[esophageal]] [[pH]] [[monitoring]].
# [[Titrate]] [[proton pump inhibitors]] [[dose]] by [[esophageal]] [[pH]] monitoring.
# [[Anti-reflux]] [[surgery]]. [[This]] [[is]] [[not]] [[more]] [[effective]] [[than]] [[medical]] [[therpay]].
# Anti-reflux [[surgery]]. This is not more effective than [[medical]] therpay.
[[Risks]] [[and]] [[benefits]] [[of]] [[long-term]] [[PPI]] [[therapy]] [[should]] [[be]] [[discussed]] [[with]] [[the]] [[patients]].
[[Risks]] and benefits of long-term [[PPI]] [[therapy]] should be discussed with the [[patients]].


* [[Do]] [[not]] [[use]] [[aspirin]] [[to]] [[prevent]] [[esophageal]] [[adenocarcinoma]] [[in]] [[the]] [[absence]] [[of]] [[other]] [[indications]] (e.g. [[cardiovascular]] [[risk factors]]). [[Although]] [[evidence]] [[suggests]] [[NSAIDs]] [[may]] [[decrease]] [[the]] [[incidence]] [[of]] [[esophageal]] [[cancer]], [[it]] [[is]] [[not]] [[clear]] [[if]] [[benefits]] [[outweight]] [[the]] [[risks]] [[of]] [[using]] [[this]] [[medications]].<ref name="pmid21376940">{{cite journal |author=Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ |title=American Gastroenterological Association medical position statement on the management of Barrett's esophagus |journal=Gastroenterology |volume=140 |issue=3 |pages=1084–91 |year=2011  |pmid=21376940 |doi=10.1053/j.gastro.2011.01.030 |url=}}</ref>
* Do not use [[aspirin]] to prevent [[esophageal]] [[adenocarcinoma]] in the absence of other indications (e.g. [[cardiovascular]] [[risk factors]]). Although [[evidence]] suggests [[NSAIDs]] may decrease the [[incidence]] of [[esophageal]] [[cancer]], it is not clear if benefits outweight the [[risks]] of using this [[medications]].<ref name="pmid21376940">{{cite journal |author=Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ |title=American Gastroenterological Association medical position statement on the management of Barrett's esophagus |journal=Gastroenterology |volume=140 |issue=3 |pages=1084–91 |year=2011  |pmid=21376940 |doi=10.1053/j.gastro.2011.01.030 |url=}}</ref>


==Secondary Prevention==
==Secondary Prevention==

Revision as of 20:09, 24 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: ; Amresh Kumar MD [2]

Overview

There are no established measures for the secondary prevention of [disease name].

OR

Effective measures for the secondary prevention of [disease name] include [strategy 1], [strategy 2], and [strategy 3].

Secondary prevention

Recommendations:

  1. Use proton pump inhibitors in doses greater than once daily. There is no evidence that higher doses produce a risk reduction in cancer.
  2. Titrate proton pump inhibitors dose by esophageal pH monitoring.
  3. Anti-reflux surgery. This is not more effective than medical therpay.

Risks and benefits of long-term PPI therapy should be discussed with the patients.

Secondary Prevention

  • There are no established measures for the secondary prevention of [disease name].

OR

  • Effective measures for the secondary prevention of [disease name] include:
    • [Strategy 1]
    • [Strategy 2]
    • [Strategy 3]

References

  1. Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ (2011). "American Gastroenterological Association medical position statement on the management of Barrett's esophagus". Gastroenterology. 140 (3): 1084–91. doi:10.1053/j.gastro.2011.01.030. PMID 21376940.

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