Budd-Chiari syndrome risk factors: Difference between revisions
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==Overivew== | ==Overivew== | ||
Approximately 80 percent of patients with the Budd-Chiari syndrome have an underlying disorder.Many patients may have more than one risk factor. Same patient may have multiple causes that predispose to the development of Budd-Chiari Syndrome. Associated risk factors include hematologic disorders, coagulopathies, chronic infections, chronic inflammatory diseases, tumors, congenital membranous obstructions. | Approximately 80 percent of [[patients]] with the Budd-Chiari syndrome have an underlying [[disorder]]. Many patients may have more than one [[risk factor]]. Same patient may have multiple [[causes]] that predispose to the [[development]] of Budd-Chiari Syndrome. Associated risk factors include hematologic disorders, [[coagulopathies]], [[chronic]] [[infections]], [[chronic]] [[inflammatory diseases]], [[tumors]], congenital membranous obstructions. | ||
==Risk Factors== | ==Risk Factors== | ||
*Approximately 80 percent of patients with the Budd-Chiari syndrome have an underlying disorder.Many patients may have more than one risk factor. Same patient may have multiple causes that predispose to the development of Budd-Chiari Syndrome.<ref name="pmid26668741">{{cite journal |vauthors=Martens P, Nevens F |title=Budd-Chiari syndrome |journal=United European Gastroenterol J |volume=3 |issue=6 |pages=489–500 |year=2015 |pmid=26668741 |pmc=4669515 |doi=10.1177/2050640615582293 |url=}}</ref><ref name="pmid27326316">{{cite journal |vauthors=Shin N, Kim YH, Xu H, Shi HB, Zhang QQ, Colon Pons JP, Kim D, Xu Y, Wu FY, Han S, Lee BB, Li LS |title=Redefining Budd-Chiari syndrome: A systematic review |journal=World J Hepatol |volume=8 |issue=16 |pages=691–702 |year=2016 |pmid=27326316 |pmc=4909431 |doi=10.4254/wjh.v8.i16.691 |url=}}</ref> | *Approximately 80 percent of [[patients]] with the [[Budd-Chiari syndrome]] have an underlying disorder. Many [[patients]] may have more than one [[Risk factors|risk factor]]. Same [[patient]] may have multiple [[causes]] that predispose to the [[development]] of Budd-Chiari Syndrome.<ref name="pmid26668741">{{cite journal |vauthors=Martens P, Nevens F |title=Budd-Chiari syndrome |journal=United European Gastroenterol J |volume=3 |issue=6 |pages=489–500 |year=2015 |pmid=26668741 |pmc=4669515 |doi=10.1177/2050640615582293 |url=}}</ref><ref name="pmid27326316">{{cite journal |vauthors=Shin N, Kim YH, Xu H, Shi HB, Zhang QQ, Colon Pons JP, Kim D, Xu Y, Wu FY, Han S, Lee BB, Li LS |title=Redefining Budd-Chiari syndrome: A systematic review |journal=World J Hepatol |volume=8 |issue=16 |pages=691–702 |year=2016 |pmid=27326316 |pmc=4909431 |doi=10.4254/wjh.v8.i16.691 |url=}}</ref> | ||
*Associated risk factors include: | *Associated [[risk factors]] include: | ||
*Hematologic disorders including: | *Hematologic disorders including: | ||
**Polycythemia rubra vera | **[[Polycythemia rubra vera]] | ||
**Paroxysmal nocturnal hemoglobinuria | **[[Paroxysmal nocturnal hemoglobinuria]] | ||
**myeloproliferative disorder | **[[Myeloproliferative disease|myeloproliferative disorder]] | ||
**Antiphospholipid antibody syndrome | **[[Antiphospholipid antibody syndrome]] | ||
**Essential thrombocytosis | **[[Essential thrombocytosis]] | ||
**Inherited thrombotic diathesis | **[[Inherited]] [[thrombotic]] diathesis | ||
*Coagulopathies include the following: | *[[Coagulopathies]] include the following: | ||
**Protein C deficiency | **[[Protein C deficiency]] | ||
**Protein S deficiency | **[[Protein S deficiency]] | ||
**Antithrombin III deficiency | **[[Antithrombin III]] [[deficiency]] | ||
**Factor V Leiden deficiency | **[[Factor V Leiden]] [[deficiency]] | ||
*Chronic infections like: | *[[Chronic]] [[infections]] like: | ||
**Hydatid cysts | **[[Hydatid cyst|Hydatid cysts]] | ||
**Aspergillosis | **[[Aspergillosis]] | ||
**Amebic abscess | **[[Amoebic liver abscess causes|Amebic abscess]] | ||
**Syphilis | **[[Syphilis]] | ||
**Tuberculosis | **[[Tuberculosis]] | ||
*Chronic inflammatory diseases such as: | *[[Chronic]] [[inflammatory diseases]] such as: | ||
**Behçet disease | **[[Behçet disease]] | ||
**Inflammatory bowel disease | **[[Inflammatory bowel disease]] | ||
**Sarcoidosis | **[[Sarcoidosis]] | ||
**Systemic lupus erythematosus | **[[Systemic lupus erythematosus]] | ||
**Sjögren syndrome | **[[Sjögren's Syndrome|Sjögren syndrome]] | ||
**Mixed connective-tissue disease | **Mixed connective-tissue disease | ||
*Tumors such as | *[[Tumors]] such as | ||
**Hepatocellular carcinoma (HCC) | **[[Hepatocellular carcinoma|Hepatocellular carcinoma (HCC)]] | ||
**Renal cell carcinoma | **[[Renal cell carcinoma]] | ||
**Leiomyosarcoma | **[[Leiomyosarcoma]] | ||
**Adrenal carcinoma | **[[Adrenal carcinoma]] | ||
**Wilms tumor | **[[Wilms' tumor|Wilms tumor]] | ||
**Right atrial myxoma | **[[Right atrial myxoma]] | ||
*Congenital membranous obstructions that includes the following: | *[[Congenital]] membranous obstructions that includes the following: | ||
**Type I: Thin membrane is present in the vena cava or the atrium | **Type I: Thin membrane is present in the [[vena cava]] or the [[atrium]] | ||
**Type II: A part of the vena cava is absent | **Type II: A part of the [[vena cava]] is absent | ||
**Type III: The inferior vena cava (IVC) cannot be filled, and collaterals have developed | **Type III: The [[Inferior vena cava|inferior vena cava (IVC)]] cannot be filled, and [[collaterals]] have developed | ||
*Miscellaneous risk factors of Budd-Chiari syndrome include the following: | *Miscellaneous [[risk factors]] of Budd-Chiari syndrome include the following: | ||
**Alpha1-antitrypsin deficiency | **[[Alpha1-antitrypsin deficiency]] | ||
**Dacarbazine | **[[Dacarbazine]] | ||
**Urethane | **Urethane | ||
**Hypoplasia of the suprahepatic veins | **[[Hypoplasia]] of the [[Hepatic veins|suprahepatic veins]] | ||
**Postsurgical obstruction | **[[Postsurgical]] [[obstruction]] | ||
**Posttraumatic obstruction | **Posttraumatic [[obstruction]] | ||
**Total parenteral nutrition (TPN): Budd-Chiari syndrome can be a complication of TPN via an IVC catheter in a neonate | **[[Total parenteral nutrition|Total parenteral nutrition (TPN)]]: Budd-Chiari syndrome can be a [[complication]] of [[TPN]] via an [[Inferior vena cava|IVC]] [[catheter]] in a [[neonate]] | ||
==References== | ==References== |
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Overivew
Approximately 80 percent of patients with the Budd-Chiari syndrome have an underlying disorder. Many patients may have more than one risk factor. Same patient may have multiple causes that predispose to the development of Budd-Chiari Syndrome. Associated risk factors include hematologic disorders, coagulopathies, chronic infections, chronic inflammatory diseases, tumors, congenital membranous obstructions.
Risk Factors
- Approximately 80 percent of patients with the Budd-Chiari syndrome have an underlying disorder. Many patients may have more than one risk factor. Same patient may have multiple causes that predispose to the development of Budd-Chiari Syndrome.[1][2]
- Associated risk factors include:
- Hematologic disorders including:
- Coagulopathies include the following:
- Chronic infections like:
- Chronic inflammatory diseases such as:
- Behçet disease
- Inflammatory bowel disease
- Sarcoidosis
- Systemic lupus erythematosus
- Sjögren syndrome
- Mixed connective-tissue disease
- Tumors such as
- Congenital membranous obstructions that includes the following:
- Type I: Thin membrane is present in the vena cava or the atrium
- Type II: A part of the vena cava is absent
- Type III: The inferior vena cava (IVC) cannot be filled, and collaterals have developed
- Miscellaneous risk factors of Budd-Chiari syndrome include the following:
- Alpha1-antitrypsin deficiency
- Dacarbazine
- Urethane
- Hypoplasia of the suprahepatic veins
- Postsurgical obstruction
- Posttraumatic obstruction
- Total parenteral nutrition (TPN): Budd-Chiari syndrome can be a complication of TPN via an IVC catheter in a neonate
References
- ↑ Martens P, Nevens F (2015). "Budd-Chiari syndrome". United European Gastroenterol J. 3 (6): 489–500. doi:10.1177/2050640615582293. PMC 4669515. PMID 26668741.
- ↑ Shin N, Kim YH, Xu H, Shi HB, Zhang QQ, Colon Pons JP, Kim D, Xu Y, Wu FY, Han S, Lee BB, Li LS (2016). "Redefining Budd-Chiari syndrome: A systematic review". World J Hepatol. 8 (16): 691–702. doi:10.4254/wjh.v8.i16.691. PMC 4909431. PMID 27326316.