Hemochromatosis historical perspective: Difference between revisions
Sunny Kumar (talk | contribs) No edit summary |
Sunny Kumar (talk | contribs) No edit summary |
||
Line 18: | Line 18: | ||
In 1935 J.H. Sheldon, a British physician, described the hereditary nature of Hemochromatosis and it's pathogensis.<ref name="pmid2659713">{{cite journal| author=Bacon BR| title=Joseph H. Sheldon and hereditary hemochromatosis: historical highlights. | journal=J Lab Clin Med | year= 1989 | volume= 113 | issue= 6 | pages= 761-2 | pmid=2659713 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2659713 }}</ref> | In 1935 J.H. Sheldon, a British physician, described the hereditary nature of Hemochromatosis and it's pathogensis.<ref name="pmid2659713">{{cite journal| author=Bacon BR| title=Joseph H. Sheldon and hereditary hemochromatosis: historical highlights. | journal=J Lab Clin Med | year= 1989 | volume= 113 | issue= 6 | pages= 761-2 | pmid=2659713 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2659713 }}</ref> | ||
In 1955, Clement A Finch, a U.S. physician, who published histological findings of Hemochroatosis in 707 patients.<ref name="pmid2219902">{{cite journal| author=Finch CA| title=Hemochromatosis--treatment is easy, diagnosis hard. | journal=West J Med | year= 1990 | volume= 153 | issue= 3 | pages= 323-5 | pmid=2219902 | doi= | pmc=1002547 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2219902 }}</ref> | |||
In 1937, Widdowson E M, McCance R A, Birtish physicans, explained iron absorption exceeds excretion in two male and female volunteer candidates.<ref name="pmid16746545">{{cite journal| author=Widdowson EM, McCance RA| title=The absorption and excretion of iron before, during and after a period of very high intake. | journal=Biochem J | year= 1937 | volume= 31 | issue= 11 | pages= 2029-34 | pmid=16746545 | doi= | pmc=1267176 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16746545 }}</ref> | |||
==References== | ==References== |
Revision as of 20:40, 11 November 2017
Hemochromatosis Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Hemochromatosis historical perspective On the Web |
American Roentgen Ray Society Images of Hemochromatosis historical perspective |
Risk calculators and risk factors for Hemochromatosis historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.
Overview
The disease was first described in 1865 by Armand Trousseau in an article on diabetes in patients with changing skin color.[1] Trousseau did not connect the diabetes with iron accumulation; instead this was done by Friedrich Daniel von Recklinghausen in 1890.[2][3] The mutation of human genome to increase iron absorption in people who are exposed to iron deficient diet is evolutionary stand point. Hemocromatosis is also known as Celtic Curse.
Historical Perspective
Irish people are most commonly affected population and existence of C282Y gene in Irish origin correlates the pathogensis and ethnicity
The migration of people from Pontic Steppe to the East in prehistory Bronze age era around 4000 years ago led to foundation of Irish population. Genome of men found from that era showed to have carrier of gene mutation C282Y.[4]
In 1865, a French Internist, Armand Trousseau wrote an article describing Hemochromatosis findings as diabetic patient with cirrhosis of the liver that expressed a bronzed skin color.r.[1]
In 1890, a German pathologist , Friedrich Daniel von Recklinghausen gave it name as Hemochromatosis.[2]
In 1935 J.H. Sheldon, a British physician, described the hereditary nature of Hemochromatosis and it's pathogensis.[5]
In 1955, Clement A Finch, a U.S. physician, who published histological findings of Hemochroatosis in 707 patients.[6]
In 1937, Widdowson E M, McCance R A, Birtish physicans, explained iron absorption exceeds excretion in two male and female volunteer candidates.[7]
References
- ↑ 1.0 1.1 name=Trousseau_1865>Trousseau A (1865). "Glycosurie, diabète sucré". Clinique médicale de l'Hôtel-Dieu de Paris. 2: 663&ndash, 98.
- ↑ 2.0 2.1 von Recklinghausen FD (1890). "Hämochromatose". Tageblatt der Naturforschenden Versammlung 1889: 324.
- ↑ Biography of Daniel von Recklinghausen
- ↑ Cassidy, Lara M.; Martiniano, Rui; Murphy, Eileen M.; Teasdale, Matthew D.; Mallory, James; Hartwell, Barrie; Bradley, Daniel G. (2016). "Neolithic and Bronze Age migration to Ireland and establishment of the insular Atlantic genome". Proceedings of the National Academy of Sciences. 113 (2): 368–373. doi:10.1073/pnas.1518445113. ISSN 0027-8424.
- ↑ Bacon BR (1989). "Joseph H. Sheldon and hereditary hemochromatosis: historical highlights". J Lab Clin Med. 113 (6): 761–2. PMID 2659713.
- ↑ Finch CA (1990). "Hemochromatosis--treatment is easy, diagnosis hard". West J Med. 153 (3): 323–5. PMC 1002547. PMID 2219902.
- ↑ Widdowson EM, McCance RA (1937). "The absorption and excretion of iron before, during and after a period of very high intake". Biochem J. 31 (11): 2029–34. PMC 1267176. PMID 16746545.