Pancreatic cancer screening: Difference between revisions
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*Screening is recommended in individuals with the following conditions who are at an increased risk of pancreatic cancer:<ref name="pmid26320426">{{cite journal| author=Goral V| title=Pancreatic Cancer: Pathogenesis and Diagnosis. | journal=Asian Pac J Cancer Prev | year= 2015 | volume= 16 | issue= 14 | pages= 5619-24 | pmid=26320426 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26320426 }} </ref> | *Screening is recommended in individuals with the following conditions who are at an increased risk of pancreatic cancer:<ref name="pmid26320426">{{cite journal| author=Goral V| title=Pancreatic Cancer: Pathogenesis and Diagnosis. | journal=Asian Pac J Cancer Prev | year= 2015 | volume= 16 | issue= 14 | pages= 5619-24 | pmid=26320426 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26320426 }} </ref> | ||
**Hereditary pancreatitis | **[[Hereditary pancreatitis]] | ||
**Familial pancreatic cancer | **[[Familial]] pancreatic cancer | ||
**Peutz-Jeghers disease | **[[Peutz-Jeghers syndrome|Peutz-Jeghers disease]] | ||
**Familial atypical mole melanoma syndrome (FAMMM) | **Familial atypical mole melanoma syndrome (FAMMM) | ||
**Cystic fibrosis of pancreas | **[[Cystic fibrosis]] of pancreas | ||
**Familial cancer syndromes such as: | **Familial cancer syndromes such as: | ||
***Lynch syndrome | ***[[Lynch syndrome]] | ||
***Familial adenomatous polyposis (FAP) | ***[[Familial adenomatous polyposis]] ([[FAP]]) | ||
*** | ***[[Von Hippel-Lindau disease|Von Hippel-Lindau syndrome]] | ||
***Multiple endocrine neoplasia type 1 | ***[[Multiple endocrine neoplasia type 1]] | ||
***Hereditary breast and ovarian cancer-BRCA1 and BRCA2 mutations | ***Hereditary [[Breast cancer|breast]] and [[ovarian cancer]] - [[BRCA1]] and [[BRCA2]] mutations | ||
==References== | ==References== | ||
Revision as of 23:26, 15 November 2017
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Pancreatic cancer Microchapters |
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Pancreatic cancer screening On the Web |
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Risk calculators and risk factors for Pancreatic cancer screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]
Overview
In asymptomatic adults who are at average risk, the U.S.P.S.T.F recommends against routine screening for pancreatic cancer due to the lack of mortality benefit. In high-risk individuals, with familial pancreatic cancer or in those with genetic syndromes predisposing to pancreatic cancer, screening is suggested. In high- risk groups, screening by endoscopic ultrasound (EUS), magnetic resonance imaging (MRI) and magnetic resonance cholangiopancreatography (MRCP) are recommended.
Screening
- In asymptomatic adults who are at average risk, the U.S.P.S.T.F recommends against routine screening for pancreatic cancer due to the lack of mortality benefit.
- In high-risk individuals, with familial pancreatic cancer or in those with genetic syndromes predisposing to pancreatic cancer, screening is suggested. In high- risk groups, screening by endoscopic ultrasound (EUS), magnetic resonance imaging (MRI) and magnetic resonance cholangiopancreatography (MRCP) are recommended.[1][2]
- Screening is recommended in individuals with the following conditions who are at an increased risk of pancreatic cancer:[3]
- Hereditary pancreatitis
- Familial pancreatic cancer
- Peutz-Jeghers disease
- Familial atypical mole melanoma syndrome (FAMMM)
- Cystic fibrosis of pancreas
- Familial cancer syndromes such as:
- Lynch syndrome
- Familial adenomatous polyposis (FAP)
- Von Hippel-Lindau syndrome
- Multiple endocrine neoplasia type 1
- Hereditary breast and ovarian cancer - BRCA1 and BRCA2 mutations
References
- ↑ Poruk KE, Firpo MA, Adler DG, Mulvihill SJ (2013). "Screening for pancreatic cancer: why, how, and who?". Ann Surg. 257 (1): 17–26. doi:10.1097/SLA.0b013e31825ffbfb. PMC 4113008. PMID 22895395.
- ↑ Greer JB, Brand RE (2007). "Screening for pancreatic cancer: current evidence and future directions". Gastroenterol Hepatol (N Y). 3 (12): 929–38. PMC 3104195. PMID 21960811.
- ↑ Goral V (2015). "Pancreatic Cancer: Pathogenesis and Diagnosis". Asian Pac J Cancer Prev. 16 (14): 5619–24. PMID 26320426.