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{{CMG}}; {{AE}} {{MKA}}
{{CMG}}; {{AE}} {{MKA}}


__NOTOC__
{{Xyz}}
{{CMG}}; {{AE}}
==Overview==
==Overview==
The most potent risk factor in the development of alcoholic liver disease is alcohol consumption. Other risk factors include female gender, hispanic ethnicity, and genetic factors.
There is no established system for the classification of [disease name].
 
OR
 
[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
 
OR
 
[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3].
[Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
 
OR
 
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
 
OR
 
If the staging system involves specific and characteristic findings and features:
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
 
OR
 
The staging of [malignancy name] is based on the [staging system].
 
OR
 
There is no established system for the staging of [malignancy name].


==Risk Factors==
==Classification==
The most potent risk factor in the development of alcoholic liver disease is the quantity and frequency of alcohol consumption. Other risk factors include gender, age, and genetic factors.<ref name="pmid23532958">{{cite journal| author=Bertola A, Park O, Gao B| title=Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: a critical role for E-selectin. | journal=Hepatology | year= 2013 | volume= 58 | issue= 5 | pages= 1814-23 | pmid=23532958 | doi=10.1002/hep.26419 | pmc=3726575 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23532958  }} </ref><ref name="pmid21538280">{{cite journal| author=Anstee QM, Daly AK, Day CP| title=Genetics of alcoholic and nonalcoholic fatty liver disease. | journal=Semin Liver Dis | year= 2011 | volume= 31 | issue= 2 | pages= 128-46 | pmid=21538280 | doi=10.1055/s-0031-1276643 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21538280  }} </ref><ref name="pmid20650922">{{cite journal| author=Altamirano J, Bataller R| title=Cigarette smoking and chronic liver diseases. | journal=Gut | year= 2010 | volume= 59 | issue= 9 | pages= 1159-62 | pmid=20650922 | doi=10.1136/gut.2008.162453 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20650922  }} </ref><ref name="pmid19215600">{{cite journal| author=Hatton J, Burton A, Nash H, Munn E, Burgoyne L, Sheron N| title=Drinking patterns, dependency and life-time drinking history in alcohol-related liver disease. | journal=Addiction | year= 2009 | volume= 104 | issue= 4 | pages= 587-92 | pmid=19215600 | doi=10.1111/j.1360-0443.2008.02493.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19215600  }} </ref><ref name="pmid17544978">{{cite journal| author=Clouston AD, Jonsson JR, Powell EE| title=Steatosis as a cofactor in other liver diseases: hepatitis C virus, alcohol, hemochromatosis, and others. | journal=Clin Liver Dis | year= 2007 | volume= 11 | issue= 1 | pages= 173-89, x | pmid=17544978 | doi=10.1016/j.cld.2007.02.007 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17544978  }} </ref><ref name="pmid12601343">{{cite journal| author=Bataller R, North KE, Brenner DA| title=Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal. | journal=Hepatology | year= 2003 | volume= 37 | issue= 3 | pages= 493-503 | pmid=12601343 | doi=10.1053/jhep.2003.50127 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12601343  }} </ref><ref name="pmid12390068">{{cite journal| author=Stewart SH| title=Racial and ethnic differences in alcohol-associated aspartate aminotransferase and gamma-glutamyltransferase elevation. | journal=Arch Intern Med | year= 2002 | volume= 162 | issue= 19 | pages= 2236-9 | pmid=12390068 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12390068  }} </ref><ref name="pmid8985274">{{cite journal| author=Naveau S, Giraud V, Borotto E, Aubert A, Capron F, Chaput JC| title=Excess weight risk factor for alcoholic liver disease. | journal=Hepatology | year= 1997 | volume= 25 | issue= 1 | pages= 108-11 | pmid=8985274 | doi=10.1002/hep.510250120 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8985274  }} </ref>


===Common Risk Factors===
*There is no established system for the classification of [disease name].
*Common risk factors in the development of alcoholic liver disease include:
OR
**Female gender<ref name="pmid8621128">{{cite journal| author=Becker U, Deis A, Sørensen TI, Grønbaek M, Borch-Johnsen K, Müller CF et al.| title=Prediction of risk of liver disease by alcohol intake, sex, and age: a prospective population study. | journal=Hepatology | year= 1996 | volume= 23 | issue= 5 | pages= 1025-9 | pmid=8621128 | doi=10.1002/hep.510230513 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8621128  }} </ref><ref name="pmid18318440">{{cite journal| author=Lee WM, Squires RH, Nyberg SL, Doo E, Hoofnagle JH| title=Acute liver failure: Summary of a workshop. | journal=Hepatology | year= 2008 | volume= 47 | issue= 4 | pages= 1401-15 | pmid=18318440 | doi=10.1002/hep.22177 | pmc=3381946 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18318440  }} </ref><ref name="pmid20949552">{{cite journal| author=Reuben A, Koch DG, Lee WM, Acute Liver Failure Study Group| title=Drug-induced acute liver failure: results of a U.S. multicenter, prospective study. | journal=Hepatology | year= 2010 | volume= 52 | issue= 6 | pages= 2065-76 | pmid=20949552 | doi=10.1002/hep.23937 | pmc=3992250 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20949552  }} </ref>
*[Disease name] may be classified according to [classification method] into [number] subtypes/groups:  
**Hispanic ethnicity<ref name="pmid25702770">{{cite journal |vauthors=Levy R, Catana AM, Durbin-Johnson B, Halsted CH, Medici V |title=Ethnic differences in presentation and severity of alcoholic liver disease |journal=Alcohol. Clin. Exp. Res. |volume=39 |issue=3 |pages=566–574 |year=2015 |pmid=25702770 |pmc=4348235 |doi=10.1111/acer.12660 |url=}}</ref>
**[Group1]
**[[Obesity]]
**[Group2]
**Genetic factors<ref name="pmid26873399">{{cite journal |vauthors=Anstee QM, Seth D, Day CP |title=Genetic Factors That Affect Risk of Alcoholic and Nonalcoholic Fatty Liver Disease |journal=Gastroenterology |volume=150 |issue=8 |pages=1728–1744.e7 |year=2016 |pmid=26873399 |doi=10.1053/j.gastro.2016.01.037 |url=}}</ref>
**[Group3]
===Less Common Risk Factors===
**[Group4]
*Less common risk factors in the development of alcoholic liver disease include:
OR
**Age
*[Disease name] may be classified into [large number > 6] subtypes based on:  
**Co-existing chronic viral hepatitis
**[Classification method 1]
**Iron overload
**[Classification method 2]
**[[Smoking]]
**[Classification method 3]
*[Disease name] may be classified into several subtypes based on:  
**[Classification method 1]
**[Classification method 2]
**[Classification method 3]
OR
*Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
OR
*If the staging system involves specific and characteristic findings and features:
*According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
OR
*The staging of [malignancy name] is based on the [staging system].
OR
*There is no established system for the staging of [malignancy name].


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 21:10, 21 November 2017


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]; Associate Editor(s)-in-Chief:

Overview

There is no established system for the classification of [disease name].

OR

[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].

OR

[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3]. [Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].

OR

Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.

OR

If the staging system involves specific and characteristic findings and features: According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].

OR

The staging of [malignancy name] is based on the [staging system].

OR

There is no established system for the staging of [malignancy name].

Classification

  • There is no established system for the classification of [disease name].

OR

  • [Disease name] may be classified according to [classification method] into [number] subtypes/groups:
    • [Group1]
    • [Group2]
    • [Group3]
    • [Group4]

OR

  • [Disease name] may be classified into [large number > 6] subtypes based on:
    • [Classification method 1]
    • [Classification method 2]
    • [Classification method 3]
  • [Disease name] may be classified into several subtypes based on:
    • [Classification method 1]
    • [Classification method 2]
    • [Classification method 3]

OR

  • Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.

OR

  • If the staging system involves specific and characteristic findings and features:
  • According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].

OR

  • The staging of [malignancy name] is based on the [staging system].

OR

  • There is no established system for the staging of [malignancy name].

References