Peptic ulcer other diagnostic studies: Difference between revisions
Jump to navigation
Jump to search
| Line 13: | Line 13: | ||
{| class="wikitable" | {| class="wikitable" | ||
|+ Diagnostic testing for ''H. pylori'' infection | |+ Diagnostic testing for ''H. pylori'' infection | ||
! Endoscopic testing !! | ! Endoscopic testing !! Prerequisites | ||
|- | |- | ||
| Rapid urease testing || Patients who have not been on a PPI within 1-2 weeks or an antibiotic or bismuth within 4 weeks of endoscopy | | Rapid urease testing || Patients who have not been on a PPI within 1-2 weeks or an antibiotic or bismuth within 4 weeks of endoscopy | ||
Revision as of 23:17, 20 November 2017
|
Peptic ulcer Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Surgery |
|
Case Studies |
|
2017 ACG Guidelines for Peptic Ulcer Disease |
|
Guidelines for the Indications to Test for, and to Treat, H. pylori Infection |
|
Guidlines for factors that predict the successful eradication when treating H. pylori infection |
|
Guidelines to document H. pylori antimicrobial resistance in the North America |
|
Guidelines for evaluation and testing of H. pylori antibiotic resistance |
|
Guidelines for when to test for treatment success after H. pylori eradication therapy |
|
Guidelines for penicillin allergy in patients with H. pylori infection |
|
Peptic ulcer other diagnostic studies On the Web |
|
American Roentgen Ray Society Images of Peptic ulcer other diagnostic studies |
|
Risk calculators and risk factors for Peptic ulcer other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
Other diagnostic studies
The methods of diagnostic testing for H. pylori can be classified into invasive and non-invasive tests:[1][2]
Invasive tests
- Endoscopy with biopsy is recommended to diagnose peptic ulcer disease.[3][4][5][6][7][8]
- Endoscopy not only helps in diagnosing PUD but also helps in ruling out cancer.
| Endoscopic testing | Prerequisites |
|---|---|
| Rapid urease testing | Patients who have not been on a PPI within 1-2 weeks or an antibiotic or bismuth within 4 weeks of endoscopy |
| Histology | Patients who have been taking a PPI, antibiotics, or bismuth, endoscopic testing should include biopsies from the gastric body and antrum |
| Culture and Polymerase Chain Reaction | Not routinely recommended |
Noninvasive tests
- Urea breath test (carbon 13) tests:Urea breath tests require the ingestion of urea labeled with the nonradioactive isotope carbon 13 or carbon 14.Proton pump inhibitors (PPIs) should be stopped for two weeks before the test. It is used to document eradication therapy and should be performed four to six weeks after completion of eradication therapy.
- Stool monoclonal antigen tests- it detect active infection and can be used as a test of cure. PPIs should be stopped for two weeks before testing.It can be done by following methods:[9][10][11][12][13]
- Enzyme immunoassay
- Immunochromatography
- Antibody tests
| Non-invasive testing | Comments | |
|---|---|---|
| Urea breath tests | Provide reliable means of identifying active H. pylori infection before antibiotic treatment and is the most reliable nonendoscopic test to document eradication of infection | |
| Serological testing | Limited use in low prevalence H. pylori populations | |
| Stool monoclonal antigen | Enzyme immunoassay | Used to detect active infection and can be used to document eradication of infection |
| Immunochromatography | ||
| Antibody tests | ||
References
- ↑ Chey WD, Wong BC, Practice Parameters Committee of the American College of Gastroenterology (2007). "American College of Gastroenterology guideline on the management of Helicobacter pylori infection". Am J Gastroenterol. 102 (8): 1808–25. doi:10.1111/j.1572-0241.2007.01393.x. PMID 17608775.
- ↑ Thijs JC, van Zwet AA, Thijs WJ, Oey HB, Karrenbeld A, Stellaard F, Luijt DS, Meyer BC, Kleibeuker JH (1996). "Diagnostic tests for Helicobacter pylori: a prospective evaluation of their accuracy, without selecting a single test as the gold standard". Am. J. Gastroenterol. 91 (10): 2125–9. PMID 8855734.
- ↑ Lieberman D, Fennerty MB, Morris CD, Holub J, Eisen G, Sonnenberg A (2004). "Endoscopic evaluation of patients with dyspepsia: results from the national endoscopic data repository". Gastroenterology. 127 (4): 1067–75. PMID 15480985.
- ↑ Delaney B, Ford AC, Forman D, Moayyedi P, Qume M (2005). "Initial management strategies for dyspepsia". Cochrane Database Syst Rev (4): CD001961. doi:10.1002/14651858.CD001961.pub2. PMID 16235292.
- ↑ Lieberman D, Fennerty MB, Morris CD, Holub J, Eisen G, Sonnenberg A (2004). "Endoscopic evaluation of patients with dyspepsia: results from the national endoscopic data repository". Gastroenterology. 127 (4): 1067–75. PMID 15480985.
- ↑ Marmo R, Rotondano G, Piscopo R, Bianco MA, Russo P, Capobianco P, Cipolletta L (2005). "Combination of age and sex improves the ability to predict upper gastrointestinal malignancy in patients with uncomplicated dyspepsia: a prospective multicentre database study". Am. J. Gastroenterol. 100 (4): 784–91. doi:10.1111/j.1572-0241.2005.40085.x. PMID 15784019.
- ↑ Talley NJ, Vakil N, Practice Parameters Committee of the American College of Gastroenterology (2005). "Guidelines for the management of dyspepsia". Am J Gastroenterol. 100 (10): 2324–37. doi:10.1111/j.1572-0241.2005.00225.x. PMID 16181387.
- ↑ Mamel JJ (1991). "Use of endoscopy in peptic ulcer disease". Med. Clin. North Am. 75 (4): 841–51. PMID 2072790.
- ↑ Korkmaz H, Kesli R, Karabagli P, Terzi Y (2013). "Comparison of the diagnostic accuracy of five different stool antigen tests for the diagnosis of Helicobacter pylori infection". Helicobacter. 18 (5): 384–91. doi:10.1111/hel.12053. PMID 23551920.
- ↑ Odaka T, Yamaguchi T, Koyama H, Saisho H, Nomura F (2002). "Evaluation of the Helicobacter pylori stool antigen test for monitoring eradication therapy". Am. J. Gastroenterol. 97 (3): 594–9. doi:10.1111/j.1572-0241.2002.05535.x. PMID 11922552.
- ↑ Shimoyama T, Sawaya M, Ishiguro A, Hanabata N, Yoshimura T, Fukuda S (2011). "Applicability of a rapid stool antigen test, using monoclonal antibody to catalase, for the management of Helicobacter pylori infection". J. Gastroenterol. 46 (4): 487–91. doi:10.1007/s00535-011-0371-4. PMID 21264478.
- ↑ Erzin Y, Altun S, Dobrucali A, Aslan M, Erdamar S, Dirican A, Kocazeybek B (2005). "Evaluation of two enzyme immunoassays for detecting Helicobacter pylori in stool specimens of dyspeptic patients after eradication therapy". J. Med. Microbiol. 54 (Pt 9): 863–6. doi:10.1099/jmm.0.45914-0. PMID 16091438.
- ↑ Asfeldt AM, Løchen ML, Straume B, Steigen SE, Florholmen J, Goll R, Nestegard O, Paulssen EJ (2004). "Accuracy of a monoclonal antibody-based stool antigen test in the diagnosis of Helicobacter pylori infection". Scand. J. Gastroenterol. 39 (11): 1073–7. doi:10.1080/00365520410007944. PMID 15545164.