Gallbladder cancer natural history: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
The prognosis is not good for most gallbladder cancer patients if the cancer is detected in its late stages. The prognosis of gallbladder cancer also depends on the following factors | The survival rate depends on the extent of cancer at the time of diagnosis with gallbladder cancer and Early detection is key for good prognosis | ||
* The prognosis is not good for most gallbladder cancer patients if the cancer is detected in its late stages. The prognosis of gallbladder cancer also depends on the following factors.<ref name="pmid26421012">{{cite journal |vauthors=Kanthan R, Senger JL, Ahmed S, Kanthan SC |title=Gallbladder Cancer in the 21st Century |journal=J Oncol |volume=2015 |issue= |pages=967472 |year=2015 |pmid=26421012 |pmc=4569807 |doi=10.1155/2015/967472 |url=}}</ref> | |||
* Among all the histological types Papillary carcinomas are having one of the best prognosis.<ref name="pmid1516000">{{cite journal |vauthors=Henson DE, Albores-Saavedra J, Corle D |title=Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates |journal=Cancer |volume=70 |issue=6 |pages=1493–7 |year=1992 |pmid=1516000 |doi= |url=}}</ref> | |||
* Intramural invasion is seen in adenocarcinomas and are associated with worst pronosis.<ref name="pmid264210122">{{cite journal |vauthors=Kanthan R, Senger JL, Ahmed S, Kanthan SC |title=Gallbladder Cancer in the 21st Century |journal=J Oncol |volume=2015 |issue= |pages=967472 |year=2015 |pmid=26421012 |pmc=4569807 |doi=10.1155/2015/967472 |url=}}</ref> | |||
*Whether or not the [[tumor]] can be removed by [[surgery]] | *Whether or not the [[tumor]] can be removed by [[surgery]] | ||
Revision as of 16:53, 30 January 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor.
Natural History
Most tumors are adenocarcinomas, with a small percent being squamous cell carcinomas. The cancer commonly spreads to the liver, pancreas, stomach and duodenum.
Prognosis
The survival rate depends on the extent of cancer at the time of diagnosis with gallbladder cancer and Early detection is key for good prognosis
- The prognosis is not good for most gallbladder cancer patients if the cancer is detected in its late stages. The prognosis of gallbladder cancer also depends on the following factors.[1]
- Among all the histological types Papillary carcinomas are having one of the best prognosis.[2]
- Intramural invasion is seen in adenocarcinomas and are associated with worst pronosis.[3]
- Whether or not the tumor can be removed by surgery
- The stage of the cancer: the size of the tumor, whether the cancer has spread outside the gallbladder
- The patient’s general health
- Whether the cancer has just been diagnosed or has recurred
References
- ↑ Kanthan R, Senger JL, Ahmed S, Kanthan SC (2015). "Gallbladder Cancer in the 21st Century". J Oncol. 2015: 967472. doi:10.1155/2015/967472. PMC 4569807. PMID 26421012.
- ↑ Henson DE, Albores-Saavedra J, Corle D (1992). "Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates". Cancer. 70 (6): 1493–7. PMID 1516000.
- ↑ Kanthan R, Senger JL, Ahmed S, Kanthan SC (2015). "Gallbladder Cancer in the 21st Century". J Oncol. 2015: 967472. doi:10.1155/2015/967472. PMC 4569807. PMID 26421012.