Glomus tumor other diagnostic studies: Difference between revisions
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***CD34 (rarely positive) | ***CD34 (rarely positive) | ||
***S100 | ***S100 | ||
* Clinical Tests | |||
** '''Love test''' | |||
*** Orientative | |||
*** Probing with a needle or pointed instrument triggers pain in the affected area but not the area immediately adjacent to it | |||
*** Sensitivity= 100% | |||
*** Specificity= 0% | |||
** '''Hildreth sign''' | |||
*** Occurence of pain following induction of ischemia by application of a tourniquet to the glomus tumor mimicking median nail dystrophy (the longitudinal splitting in the midline of the nail) | |||
*** Highlights the vascular nature of the lesion | |||
*** Sensitivity= 77.4% - 92% | |||
*** Specificity= 91% - 100% | |||
** '''Cold-sensitivity test''' | |||
*** Application of cold water or ethanol to the affected area reproducing the symptoms | |||
*** Sensitivity= 100% | |||
*** Specificity= 100% | |||
** '''Transillumination test''' | |||
*** Performed in a darkened room by passing light through the finger pad | |||
*** An opaque red image is observed in the region of the tumor that allows estimation of its size | |||
*** Sensitivity= 23% - 38% | |||
*** Specificity= 90% | |||
==References== | ==References== | ||
Revision as of 23:42, 6 May 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
Other diagnostic studies for glomus tumor include immunohistochemistry staining, which demonstrates glomus cells positive for vimentin and alpha-smooth muscle actin and negative for desmin.[1]
Other Diagnostic Studies
- Other diagnostic studies for glomus tumor include immunohistochemistry staining, which demonstrates the following:[1]
- Clinical Tests
- Love test
- Orientative
- Probing with a needle or pointed instrument triggers pain in the affected area but not the area immediately adjacent to it
- Sensitivity= 100%
- Specificity= 0%
- Hildreth sign
- Occurence of pain following induction of ischemia by application of a tourniquet to the glomus tumor mimicking median nail dystrophy (the longitudinal splitting in the midline of the nail)
- Highlights the vascular nature of the lesion
- Sensitivity= 77.4% - 92%
- Specificity= 91% - 100%
- Cold-sensitivity test
- Application of cold water or ethanol to the affected area reproducing the symptoms
- Sensitivity= 100%
- Specificity= 100%
- Transillumination test
- Performed in a darkened room by passing light through the finger pad
- An opaque red image is observed in the region of the tumor that allows estimation of its size
- Sensitivity= 23% - 38%
- Specificity= 90%
- Love test
References
- ↑ 1.0 1.1 Kaye VM, Dehner LP (1991). "Cutaneous glomus tumor. A comparative immunohistochemical study with pseudoangiomatous intradermal melanocytic nevi". Am J Dermatopathol. 13 (1): 2–6. PMID 1848411.