Non-Hodgkin lymphoma biopsy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Preeti Singh, M.B.B.S.[2]

Overview

Lymph node or extranodal tissue biopsy is diagnostic of non-Hodgkin lymphoma.

Biopsy

• Lymph node or extranodal tissue biopsy is diagnostic of non-Hodgkin lymphoma.
• Biopsy findings vary in morphologic features depending on the specific subtype.
• he abnormal lymphocytes in the lymph node, bone marrow, or extranodal sites can be subdivided as small cleaved or noncleaved, intermediate, or large cell and can have a follicular or diffuse pattern.
• Lymphomas usually alter the lymph node architecture, and the capsule is usually involved.