Primary cutaneous follicle centre lymphoma medical therapy: Difference between revisions
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* Approximately one-third of primary cutaneous follicle centre lymphoma relapse, usually in the skin; treatment is similar to initial management<ref name="Wilcox2015">{{cite journal |authors=Wilcox RA |title=Cutaneous B-cell lymphomas: 2015 update on diagnosis, risk-stratification, and management |journal=Am. J. Hematol. |volume=90 |issue=1 |pages=73–6 |year=2015 |pmid=25535037 |doi=10.1002/ajh.23863 |url=}}</ref> and overall survival remains excellent.<ref name="Suárez2013_2">{{cite journal |vauthors=Suárez AL, Querfeld C, Horwitz S, etal |title=Primary cutaneous B-cell lymphomas: part II. Therapy and future directions |journal=J. Am. Acad. Dermatol. |volume=69 |issue=3 |pages=343.e1–11; quiz 355–6 |year=2013 |pmid=23957985 |doi=10.1016/j.jaad.2013.06.011 |url=}}</ref> | * Approximately one-third of primary cutaneous follicle centre lymphoma relapse, usually in the skin; treatment is similar to initial management<ref name="Wilcox2015">{{cite journal |authors=Wilcox RA |title=Cutaneous B-cell lymphomas: 2015 update on diagnosis, risk-stratification, and management |journal=Am. J. Hematol. |volume=90 |issue=1 |pages=73–6 |year=2015 |pmid=25535037 |doi=10.1002/ajh.23863 |url=}}</ref> and overall survival remains excellent.<ref name="Suárez2013_2">{{cite journal |vauthors=Suárez AL, Querfeld C, Horwitz S, etal |title=Primary cutaneous B-cell lymphomas: part II. Therapy and future directions |journal=J. Am. Acad. Dermatol. |volume=69 |issue=3 |pages=343.e1–11; quiz 355–6 |year=2013 |pmid=23957985 |doi=10.1016/j.jaad.2013.06.011 |url=}}</ref> | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 15:48, 30 May 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overvew
The predominant therapy for primary cutaneous follicle centre lymphoma is radiotherapy. Adjunctive chemotherapy may be required.[1][2]
Medical Therapy
- Surgical removal and/or radiotherapy is given for localized disease.[1][2]
- Radiation using multiple radiation fields is given if the disease has wider extent with grouped lesions.[1]:314[3][4][2]
- For the less common situation of more extensive disease (still confined to skin), rituximab without chemotherapy is used.[1][3][4][2]Intralesional interferon alpha (IFN-α)[5]and intralesional rituximab have been used.[1][5]
- Approximately one-third of primary cutaneous follicle centre lymphoma relapse, usually in the skin; treatment is similar to initial management[2] and overall survival remains excellent.[6]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Jaffe, ES (2011). Hematopathology (1st ed.). Elsevier Saunders. ISBN 9780721600406. Unknown parameter
|coauthors=
ignored (help) - ↑ 2.0 2.1 2.2 2.3 2.4 Wilcox RA (2015). "Cutaneous B-cell lymphomas: 2015 update on diagnosis, risk-stratification, and management". Am. J. Hematol. 90 (1): 73–6. doi:10.1002/ajh.23863. PMID 25535037.
- ↑ 3.0 3.1 Armitage, JO; Mauch PM; Harris NL; et al. (2010). "Chapter 24". Non-Hodgkin Lymphomas (2nd ed.). Lippincott Williams & Wilkins. ISBN 9780781791168.
- ↑ 4.0 4.1 Sokol L, Naghashpour M, Glass LF (2012). "Primary cutaneous B-cell lymphomas: recent advances in diagnosis and management". Cancer Control. 19 (3): 236–44. PMID 22710899.
- ↑ 5.0 5.1 Senff NJ, Noordijk EM, Kim YH, et al. (2008). "European Organization for Research and Treatment of Cancer and International Society for Cutaneous Lymphoma consensus recommendations for the management of cutaneous B-cell lymphomas". Blood. 112 (5): 1600–9. doi:10.1182/blood-2008-04-152850. PMID 18567836.
- ↑ Suárez AL, Querfeld C, Horwitz S, et al. (2013). "Primary cutaneous B-cell lymphomas: part II. Therapy and future directions". J. Am. Acad. Dermatol. 69 (3): 343.e1–11, quiz 355–6. doi:10.1016/j.jaad.2013.06.011. PMID 23957985.