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| ==Classification== | | ==Classification== |
| :* 1. '''World Health Organization classification of CNS teratoma'''<ref name="pmid9046301">{{cite journal| author=Matsutani M, Sano K, Takakura K, Fujimaki T, Nakamura O, Funata N et al.| title=Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases. | journal=J Neurosurg | year= 1997 | volume= 86 | issue= 3 | pages= 446-55 | pmid=9046301 | doi=10.3171/jns.1997.86.3.0446 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9046301 }} </ref>
| | There is no established system for the classification of [disease name]. |
| :::* Teratoma.
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| ::::* Immature.
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| ::::* Mature.
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| ::::* Teratoma with malignant transformation.
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| :* 2. '''Childhood Extracranial teratoma classification'''
| | OR |
| ::* 2.1 GCTs arise from primordial germ cells, which migrate during embryogenesis from the yolk sac through the mesentery to the gonads.<ref name="pmid6343221">{{cite journal| author=Dehner LP| title=Gonadal and extragonadal germ cell neoplasia of childhood. | journal=Hum Pathol | year= 1983 | volume= 14 | issue= 6 | pages= 493-511 | pmid=6343221 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6343221 }} </ref><ref name="pmid18381640">{{cite journal| author=McIntyre A, Gilbert D, Goddard N, Looijenga L, Shipley J| title=Genes, chromosomes and the development of testicular germ cell tumors of adolescents and adults. | journal=Genes Chromosomes Cancer | year= 2008 | volume= 47 | issue= 7 | pages= 547-57 | pmid=18381640 | doi=10.1002/gcc.20562 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18381640 }} </ref> Childhood extracranial GCTs can be divided into the following two types:
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| ::::* Gonadal.
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| ::::* Extragonadal.
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| ::* 2.2 Most childhood extragonadal teratoma arise in midline sites (i.e., sacrococcygeal, mediastinal, and retroperitoneal); the midline location may represent aberrant embryonic migration of the primordial germ cells.Childhood extracranial teratoma are broadly classified as the following:
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| ::::* Mature teratomas.
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| ::::* Immature teratomas.
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| ::* 2.3 Pediatric teratoma Biology
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| :::* The following biologically distinct subtypes of teratoma are found in children and adolescents:
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| ::::* Testicular.
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| ::::* Ovarian.
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| ::::* Extragonadal extracranial.
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| :*3. '''Cellular Classification of Ovarian Teratoma'''
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| ::* The following histologic subtypes have been described.<ref name="pmid8381708">{{cite journal| author=Gershenson DM| title=Update on malignant ovarian germ cell tumors. | journal=Cancer | year= 1993 | volume= 71 | issue= 4 Suppl | pages= 1581-90 | pmid=8381708 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8381708 }} </ref><ref>Serov SF, Scully RE, Robin IH: International Histologic Classification of Tumours: No. 9. Histological Typing of Ovarian Tumours. Geneva: World Health Organization, 1973.</ref>
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| :::* Teratoma.
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| ::::* Immature.
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| ::::* Mature.
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| ::::::* Solid.
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| ::::::* Cystic.
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| :::::::* [[Dermoid cyst]] (mature cystic teratoma).
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| :::::::* [[Dermoid cyst]] with malignant transformation.
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| :::* Monodermal and highly specialized.
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| :::::* Struma ovarii.
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| :::::* Carcinoid.
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| :::::* Struma ovarii and carcinoid.
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| :::::* Others (e.g., malignant neuroectodermal and ependymoma).
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| :* 4. '''Cellular Classification of Testicular Cancer''' <ref>Woodward PJ, Heidenreich A, Looijenga LHJ, et al.: Germ cell tumours. In: Eble JN, Sauter G, Epstein JI, et al.: Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon, France: IARC Press, 2004, pp 221-49.</ref><ref>Ulbright TM, Berney DM: Testicular and paratesticular tumors. In: Mills SE, Carter D, Greenson JK, et al., eds.: Sternberg's Diagnostic Surgical Pathology. Philadelphia, Pa: Lippincott Williams & Wilkins, 2010, pp 1944-2004.</ref><ref>Bosi GJ, Feldman DR, Bajorin DE, et al.: Cancer of the testis. In: DeVita VT Jr, Lawrence TS, Rosenberg SA: Cancer: Principles and Practice of Oncology. 9th ed. Philadelphia, Pa: Lippincott Williams & Wilkins, 2011, pp 1280-1301</ref>
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| ::* 4.1 Malignant pure germ cell tumor (showing a single-cell type):
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| ::::* Teratoma. | | [Disease name] may be classified according to [classification method] into [number] subtypes/groups: |
| ::* 4.2 Malignant mixed germ cell tumor (showing more than one histologic pattern): | | |
| ::::* Embryonal carcinoma and teratoma with or without seminoma. | | * [Group1] |
| ::::* Yolk sac tumor and teratoma with or without seminoma. | | * [Group2] |
| | * [Group3] |
| | * [Group4] |
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| | OR |
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| | [Disease name] may be classified into [large number > 6] subtypes based on: |
| | |
| | * [Classification method 1] |
| | * [Classification method 2] |
| | * [Classification method 3] |
| | |
| | [Disease name] may be classified into several subtypes based on: |
| | |
| | * [Classification method 1] |
| | * [Classification method 2] |
| | * [Classification method 3] |
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| | OR |
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| | Based on the duration of symptoms, [disease name] may be classified as either acute or chronic. |
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| | OR |
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| | '''If the staging system involves specific and characteristic findings and features:''' |
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| | According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2]. |
| | |
| | OR |
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| | The staging of [malignancy name] is based on the [staging system]. |
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| | OR |
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| | There is no established system for the staging of [malignancy name]. |
| | |
| | :::::::* |
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| ==References== | | ==References== |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
Classification
There is no established system for the classification of [disease name].
OR
[Disease name] may be classified according to [classification method] into [number] subtypes/groups:
- [Group1]
- [Group2]
- [Group3]
- [Group4]
OR
[Disease name] may be classified into [large number > 6] subtypes based on:
- [Classification method 1]
- [Classification method 2]
- [Classification method 3]
[Disease name] may be classified into several subtypes based on:
- [Classification method 1]
- [Classification method 2]
- [Classification method 3]
OR
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
OR
If the staging system involves specific and characteristic findings and features:
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
OR
The staging of [malignancy name] is based on the [staging system].
OR
There is no established system for the staging of [malignancy name].
References