Mesenteric ischemia laboratory findings: Difference between revisions
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High serum levels of | High serum levels of | ||
* Serum amylase | * Serum amylase | ||
* Aspartate aminotransferase | * Aspartate aminotransferase | ||
* Lactate dehydrogenase | * Lactate dehydrogenase | ||
* Creatine phosphokinase | * Creatine phosphokinase | ||
Abnormality in the lab findings is mostly seen after the infarction of the bowel has ensued. However, any patient with unrecognized abdominal pain and high anion gap metabolic acidosis should be ruled out for mesenteric ischemia. | Abnormality in the lab findings is mostly seen after the infarction of the bowel has ensued. However, any patient with unrecognized abdominal pain and high anion gap metabolic acidosis should be ruled out for mesenteric ischemia. | ||
'''Laboratory findings when bowel necrosis has occured:''' | |||
* Hyperphosphatemia | |||
* Hyperkalemia | |||
==References== | ==References== | ||
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Overview
Laboratory Findings
The commonly seen laboratory findings in mesenteric ischemia include:[1][2][3][4][5]
Early findings:
(More sensitive)
- Hemoconcentration
- High anion gap metabolic acidosis
- Lactic acidosis
(Less sensitive)
High serum levels of
- Serum amylase
- Aspartate aminotransferase
- Lactate dehydrogenase
- Creatine phosphokinase
Abnormality in the lab findings is mostly seen after the infarction of the bowel has ensued. However, any patient with unrecognized abdominal pain and high anion gap metabolic acidosis should be ruled out for mesenteric ischemia.
Laboratory findings when bowel necrosis has occured:
- Hyperphosphatemia
- Hyperkalemia
References
- ↑ Graeber GM, Cafferty PJ, Wolf RE, Harmon JW (1984). "An analysis of creatine phosphokinase in the mucosa and the muscularis of the gastrointestinal tract". J Surg Res. 37 (5): 376–82. PMID 6333551.
- ↑ Graeber GM, Wukich DK, Cafferty PJ, O'Neill JF, Wolf RE, Ackerman NB; et al. (1981). "Changes in peripheral serum creatine phosphokinase (CPK) and lactic dehydrogenase (LDH) in acute experimental colonic infarction". Ann Surg. 194 (6): 708–15. PMC 1345383. PMID 7305484 : 7305484 Check
|pmid=value (help). - ↑ Graeber GM, Cafferty PJ, Reardon MJ, Curley CP, Ackerman NB, Harmon JW (1981). "Changes in serum total creatine phosphokinase (CPK) and its isoenzymes caused by experimental ligation of the superior mesenteric artery". Ann Surg. 193 (4): 499–505. PMC 1345104. PMID 7212812.
- ↑ Glenister KM, Corke CF (2004). "Infarcted intestine: a diagnostic void". ANZ J Surg. 74 (4): 260–5. doi:10.1111/j.1445-2197.2004.02956.x. PMID 15043738.
- ↑ Zhang FX, Ma BB, Liang GZ, Zhang H (2011). "Analysis of serum enzyme levels in a rabbit model of acute mesenteric ischemia". Mol Med Rep. 4 (6): 1095–9. doi:10.3892/mmr.2011.553. PMID 21842126.