Hepatic encephalopathy causes: Difference between revisions
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==Overview== | ==Overview== | ||
The most common cause of hepatic encephalopathy is hepatic cirrhosis, drug and toxins and acute fulminant hepatitis. Less common causes of hepatic encephalopathy include Wilson's disease, porphyria, | The most common cause of hepatic encephalopathy is [[hepatic cirrhosis]], drug and toxins and [[Fulminant hepatitis|acute fulminant hepatitis]]. Less common causes of hepatic encephalopathy include [[Wilson's disease]], [[porphyria]], [[Alpha 1-antitrypsin deficiency|alpha-1-antitripsin deficiency]], [[autoimmune hepatitis]], [[Budd-Chiari syndrome|Budd-chiari syndrome]], cancer(primary [[hepatic cancer]] or [[metastasis]] to liver), [[HELLP syndrome]]([[hemolysis]], elevated [[liver function tests]], and low [[Platelet|platelets]]) and [[sepsis]]. | ||
==Causes== | ==Causes== | ||
=== Common Causes === | === Common Causes === | ||
Common causes of hepatic encephalopathy include: | Common causes of hepatic encephalopathy include: | ||
* Hepatic cirrhosis | * [[Hepatic cirrhosis]] | ||
* Drug and toxins(acetaminophen, amoxicilin/clavulanate, halothane, iron, NSAIDs, isoniazid ,carbon tetrachloride, Wild mushroom Amanita phalloides) | * Drug and toxins([[acetaminophen]], [[Amoxicilina|amoxicilin]]/[[Clavulanic acid|clavulanate]], [[halothane]], [[iron]], [[NSAIDs]], [[isoniazid]] ,[[carbon tetrachloride]], Wild mushroom [[Amanita phalloides]]) | ||
* Acute fulminant viral hepatitis | * Acute [[fulminant]] [[viral hepatitis]] | ||
===Less Common Causes=== | ===Less Common Causes=== | ||
Less common causes of hepatic encephalopathy include: | Less common causes of hepatic encephalopathy include: | ||
*Wilson’s disease | *[[Wilson's disease|Wilson’s disease]] | ||
*Porphyria | *[[Porphyria]] | ||
*Alpha-1-antitripsin deficiency | *[[Alpha 1-antitrypsin deficiency|Alpha-1-antitripsin deficiency]] | ||
*Autoimmune hepatitis | *[[Autoimmune hepatitis]] | ||
*Budd-chiari syndrome | *[[Budd-Chiari syndrome|Budd-chiari syndrome]] | ||
*Cancer(primary hepatic cancer or metastasis to liver) | *[[Cancer]](primary hepatic cancer or [[metastasis]] to liver) | ||
*HELLP syndrome(hemolysis, elevated liver function tests, and low platelets) | *[[HELLP syndrome]]([[hemolysis]], elevated [[liver function tests]], and low [[Platelet|platelets]]) | ||
*Sepsis | *[[Sepsis]] | ||
*[[Right heart failure]] | |||
===Causes by Organ System=== | ===Causes by Organ System=== | ||
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{| style="width:80%; height:100px" border="1" | {| style="width:80%; height:100px" border="1" | ||
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular''' | | style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular''' | ||
| style="width:75%" bgcolor="Beige" ; border="1" | | | style="width:75%" bgcolor="Beige" ; border="1" |[[Budd-Chiari syndrome|Budd-chiari syndrome]] | ||
Right heart failure | [[Right heart failure]] | ||
|- | |- | ||
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning''' | | bgcolor="LightSteelBlue" | '''Chemical/Poisoning''' | ||
| bgcolor="Beige" | Drug and | | bgcolor="Beige" | Drug and [[toxin]]<nowiki/>s([[acetaminophen]], [[Amoxicilina|amoxicilin]]/[[Clavulanic acid|clavulanate]], [[halothane]], [[iron]], [[NSAIDs]], [[isoniazid]] ,[[carbon tetrachloride]], Wild mushroom [[Amanita phalloides]]) | ||
|- | |- | ||
|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
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|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Gastroenterologic''' | | '''Gastroenterologic''' | ||
| bgcolor="Beige" | Hepatic cirrhosis, acute fulminant viral hepatitis, Wilson's disease, hemochromatosis, alpha-1-antitripsin deficiency, autoimmune hepatitis, cancer(primary hepatic cancer or metastasis to liver) | | bgcolor="Beige" | [[Hepatic cirrhosis]], acute [[fulminant]] [[viral hepatitis]], [[Wilson's disease]], [[hemochromatosis]], [[Alpha 1-antitrypsin deficiency|alpha-1-antitripsin deficiency]], [[autoimmune hepatitis]], [[cancer]](primary hepatic cancer or [[metastasis]] to liver) | ||
|- | |- | ||
|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
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|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Hematologic''' | | '''Hematologic''' | ||
| bgcolor="Beige" | Porphyria, HELLP syndrome (hemolysis, elevated liver function tests, and low platelets) | | bgcolor="Beige" | [[Porphyria]], [[HELLP syndrome]] ([[hemolysis]], elevated [[liver function tests]], and low [[Platelet|platelets]]) | ||
|- | |- | ||
|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
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|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Infectious Disease''' | | '''Infectious Disease''' | ||
| bgcolor="Beige" |Sepsis | | bgcolor="Beige" |[[Sepsis]] | ||
|- | |- | ||
|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" |
Revision as of 18:26, 14 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: ;Mohamadmostafa Jahansouz M.D.[2]
Overview
The most common cause of hepatic encephalopathy is hepatic cirrhosis, drug and toxins and acute fulminant hepatitis. Less common causes of hepatic encephalopathy include Wilson's disease, porphyria, alpha-1-antitripsin deficiency, autoimmune hepatitis, Budd-chiari syndrome, cancer(primary hepatic cancer or metastasis to liver), HELLP syndrome(hemolysis, elevated liver function tests, and low platelets) and sepsis.
Causes
Common Causes
Common causes of hepatic encephalopathy include:
- Hepatic cirrhosis
- Drug and toxins(acetaminophen, amoxicilin/clavulanate, halothane, iron, NSAIDs, isoniazid ,carbon tetrachloride, Wild mushroom Amanita phalloides)
- Acute fulminant viral hepatitis
Less Common Causes
Less common causes of hepatic encephalopathy include:
- Autoimmune hepatitis
- Budd-chiari syndrome
- Cancer(primary hepatic cancer or metastasis to liver)
- HELLP syndrome(hemolysis, elevated liver function tests, and low platelets)
- Sepsis
- Right heart failure
Causes by Organ System
Cardiovascular | Budd-chiari syndrome |
Chemical/Poisoning | Drug and toxins(acetaminophen, amoxicilin/clavulanate, halothane, iron, NSAIDs, isoniazid ,carbon tetrachloride, Wild mushroom Amanita phalloides) |
Dental | No underlying causes |
Dermatologic | No underlying causes |
Drug Side Effect | No underlying causes |
Ear Nose Throat | No underlying causes |
Endocrine | No underlying causes |
Environmental | No underlying causes |
Gastroenterologic | Hepatic cirrhosis, acute fulminant viral hepatitis, Wilson's disease, hemochromatosis, alpha-1-antitripsin deficiency, autoimmune hepatitis, cancer(primary hepatic cancer or metastasis to liver) |
Genetic | No underlying causes |
Hematologic | Porphyria, HELLP syndrome (hemolysis, elevated liver function tests, and low platelets) |
Iatrogenic | No underlying causes |
Infectious Disease | Sepsis |
Musculoskeletal/Orthopedic | No underlying causes |
Neurologic | No underlying causes |
Nutritional/Metabolic | No underlying causes |
Obstetric/Gynecologic | No underlying causes |
Oncologic | No underlying causes |
Ophthalmologic | No underlying causes |
Overdose/Toxicity | No underlying causes |
Psychiatric | No underlying causes |
Pulmonary | No underlying causes |
Renal/Electrolyte | No underlying causes |
Rheumatology/Immunology/Allergy | No underlying causes |
Sexual | No underlying causes |
Trauma | No underlying causes |
Urologic | No underlying causes |
Miscellaneous | No underlying causes |
Causes in Alphabetical Order
List the causes of the disease in alphabetical order.