Lactose intolerance natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
If left untreated, | If left untreated, patients with lactose intoelrance may progress to develop malnutrition, osteomalacia , and osteopenia. Common complications of lactose intoelrance include [complication 1], [complication 2], and [complication 3]. | ||
Common complications of | |||
OR | OR | ||
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**Bloating | **Bloating | ||
**Watery, frothy and bulky diarrhea | **Watery, frothy and bulky diarrhea | ||
*If left untreated patients with lactose intolerance may progress to develop: | |||
**Malnutrition | |||
**Osteomalacia | |||
**Osteopenia | |||
===Complications=== | ===Complications=== | ||
Children and adults who are lactose intolerant and do not intake adequate quantities of dairy products may become depleted of calcium<ref name="pmid228266392">{{cite journal |vauthors=Mattar R, de Campos Mazo DF, Carrilho FJ |title=Lactose intolerance: diagnosis, genetic, and clinical factors |journal=Clin Exp Gastroenterol |volume=5 |issue= |pages=113–21 |year=2012 |pmid=22826639 |pmc=3401057 |doi=10.2147/CEG.S32368 |url=}}</ref><ref name="pmid264043642">{{cite journal |vauthors=Silanikove N, Leitner G, Merin U |title=The Interrelationships between Lactose Intolerance and the Modern Dairy Industry: Global Perspectives in Evolutional and Historical Backgrounds |journal=Nutrients |volume=7 |issue=9 |pages=7312–31 |year=2015 |pmid=26404364 |pmc=4586535 |doi=10.3390/nu7095340 |url=}}</ref><ref name="pmid27882862">{{cite journal |vauthors=Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A |title=Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence |journal=Food Nutr Res |volume=60 |issue= |pages=32527 |year=2016 |pmid=27882862 |pmc=5122229 |doi= |url=}}</ref> | Children and adults who are lactose intolerant and do not intake adequate quantities of dairy products may become depleted of calcium | ||
*Common complications of lactose intolerance if they do not intake adequate quantities of dairy products and calcium include: <ref name="pmid228266392">{{cite journal |vauthors=Mattar R, de Campos Mazo DF, Carrilho FJ |title=Lactose intolerance: diagnosis, genetic, and clinical factors |journal=Clin Exp Gastroenterol |volume=5 |issue= |pages=113–21 |year=2012 |pmid=22826639 |pmc=3401057 |doi=10.2147/CEG.S32368 |url=}}</ref><ref name="pmid264043642">{{cite journal |vauthors=Silanikove N, Leitner G, Merin U |title=The Interrelationships between Lactose Intolerance and the Modern Dairy Industry: Global Perspectives in Evolutional and Historical Backgrounds |journal=Nutrients |volume=7 |issue=9 |pages=7312–31 |year=2015 |pmid=26404364 |pmc=4586535 |doi=10.3390/nu7095340 |url=}}</ref><ref name="pmid27882862">{{cite journal |vauthors=Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A |title=Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence |journal=Food Nutr Res |volume=60 |issue= |pages=32527 |year=2016 |pmid=27882862 |pmc=5122229 |doi= |url=}}</ref> | |||
**Osteopenia | **Osteopenia | ||
**Osteoporosis | **Osteoporosis | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
Overview
If left untreated, patients with lactose intoelrance may progress to develop malnutrition, osteomalacia , and osteopenia. Common complications of lactose intoelrance include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of lactose intoelrance usually develop after age of 6 and start with symptoms such as:[1][2][3]
- Abdominal pain
- Flatulence
- Bloating
- Watery, frothy and bulky diarrhea
- If left untreated patients with lactose intolerance may progress to develop:
- Malnutrition
- Osteomalacia
- Osteopenia
Complications
Children and adults who are lactose intolerant and do not intake adequate quantities of dairy products may become depleted of calcium
- Common complications of lactose intolerance if they do not intake adequate quantities of dairy products and calcium include: [4][5][6]
- Osteopenia
- Osteoporosis
- Malnutrition
- Rickets
- Osteomalacia
Prognosis
- Prognosis is generally excellent
References
- ↑ Szilagyi A (2015). "Adult lactose digestion status and effects on disease". Can J Gastroenterol Hepatol. 29 (3): 149–56. PMC 4399375. PMID 25855879.
- ↑ Suarez FL, Savaiano DA, Levitt MD (1995). "A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance". N. Engl. J. Med. 333 (1): 1–4. doi:10.1056/NEJM199507063330101. PMID 7776987.
- ↑ Mattar R, de Campos Mazo DF, Carrilho FJ (2012). "Lactose intolerance: diagnosis, genetic, and clinical factors". Clin Exp Gastroenterol. 5: 113–21. doi:10.2147/CEG.S32368. PMC 3401057. PMID 22826639.
- ↑ Mattar R, de Campos Mazo DF, Carrilho FJ (2012). "Lactose intolerance: diagnosis, genetic, and clinical factors". Clin Exp Gastroenterol. 5: 113–21. doi:10.2147/CEG.S32368. PMC 3401057. PMID 22826639.
- ↑ Silanikove N, Leitner G, Merin U (2015). "The Interrelationships between Lactose Intolerance and the Modern Dairy Industry: Global Perspectives in Evolutional and Historical Backgrounds". Nutrients. 7 (9): 7312–31. doi:10.3390/nu7095340. PMC 4586535. PMID 26404364.
- ↑ Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A (2016). "Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence". Food Nutr Res. 60: 32527. PMC 5122229. PMID 27882862.