Lactose intolerance natural history, complications and prognosis: Difference between revisions
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===Natural History=== | ===Natural History=== | ||
*The [[Symptom|symptoms]] of lactose intoelrance usually develop after age of 6 and start with symptoms such as:<ref name="pmid25855879">{{cite journal |vauthors=Szilagyi A |title=Adult lactose digestion status and effects on disease |journal=Can J Gastroenterol Hepatol |volume=29 |issue=3 |pages=149–56 |year=2015 |pmid=25855879 |pmc=4399375 |doi= |url=}}</ref><ref name="pmid7776987">{{cite journal |vauthors=Suarez FL, Savaiano DA, Levitt MD |title=A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance |journal=N. Engl. J. Med. |volume=333 |issue=1 |pages=1–4 |year=1995 |pmid=7776987 |doi=10.1056/NEJM199507063330101 |url=}}</ref><ref name="pmid22826639">{{cite journal |vauthors=Mattar R, de Campos Mazo DF, Carrilho FJ |title=Lactose intolerance: diagnosis, genetic, and clinical factors |journal=Clin Exp Gastroenterol |volume=5 |issue= |pages=113–21 |year=2012 |pmid=22826639 |pmc=3401057 |doi=10.2147/CEG.S32368 |url=}}</ref> | *The [[Symptom|symptoms]] of lactose intoelrance usually develop after age of 6 and start with [[Symptom|symptoms]] such as:<ref name="pmid25855879">{{cite journal |vauthors=Szilagyi A |title=Adult lactose digestion status and effects on disease |journal=Can J Gastroenterol Hepatol |volume=29 |issue=3 |pages=149–56 |year=2015 |pmid=25855879 |pmc=4399375 |doi= |url=}}</ref><ref name="pmid7776987">{{cite journal |vauthors=Suarez FL, Savaiano DA, Levitt MD |title=A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance |journal=N. Engl. J. Med. |volume=333 |issue=1 |pages=1–4 |year=1995 |pmid=7776987 |doi=10.1056/NEJM199507063330101 |url=}}</ref><ref name="pmid22826639">{{cite journal |vauthors=Mattar R, de Campos Mazo DF, Carrilho FJ |title=Lactose intolerance: diagnosis, genetic, and clinical factors |journal=Clin Exp Gastroenterol |volume=5 |issue= |pages=113–21 |year=2012 |pmid=22826639 |pmc=3401057 |doi=10.2147/CEG.S32368 |url=}}</ref> | ||
**Abdominal pain | **[[Abdominal pain]] | ||
**Flatulence | **[[Flatulence]] | ||
**Bloating | **[[Bloating]] | ||
**Watery, frothy and bulky diarrhea | **Watery, frothy and bulky [[diarrhea]] | ||
*If left untreated, patients with lactose intolerance may progress to develop: | *If left untreated, patients with lactose intolerance may progress to develop: | ||
**Malnutrition | **[[Malnutrition]] | ||
**Osteomalacia | **[[Osteomalacia]] | ||
**Osteopenia | **[[Osteopenia]] | ||
===Complications=== | ===Complications=== | ||
*Common complications of lactose intolerance if they do not intake adequate quantities of dairy products and calcium include: <ref name="pmid228266392">{{cite journal |vauthors=Mattar R, de Campos Mazo DF, Carrilho FJ |title=Lactose intolerance: diagnosis, genetic, and clinical factors |journal=Clin Exp Gastroenterol |volume=5 |issue= |pages=113–21 |year=2012 |pmid=22826639 |pmc=3401057 |doi=10.2147/CEG.S32368 |url=}}</ref><ref name="pmid264043642">{{cite journal |vauthors=Silanikove N, Leitner G, Merin U |title=The Interrelationships between Lactose Intolerance and the Modern Dairy Industry: Global Perspectives in Evolutional and Historical Backgrounds |journal=Nutrients |volume=7 |issue=9 |pages=7312–31 |year=2015 |pmid=26404364 |pmc=4586535 |doi=10.3390/nu7095340 |url=}}</ref><ref name="pmid27882862">{{cite journal |vauthors=Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A |title=Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence |journal=Food Nutr Res |volume=60 |issue= |pages=32527 |year=2016 |pmid=27882862 |pmc=5122229 |doi= |url=}}</ref> | *Common complications of lactose intolerance if they do not intake adequate quantities of dairy products and [[calcium]] include: <ref name="pmid228266392">{{cite journal |vauthors=Mattar R, de Campos Mazo DF, Carrilho FJ |title=Lactose intolerance: diagnosis, genetic, and clinical factors |journal=Clin Exp Gastroenterol |volume=5 |issue= |pages=113–21 |year=2012 |pmid=22826639 |pmc=3401057 |doi=10.2147/CEG.S32368 |url=}}</ref><ref name="pmid264043642">{{cite journal |vauthors=Silanikove N, Leitner G, Merin U |title=The Interrelationships between Lactose Intolerance and the Modern Dairy Industry: Global Perspectives in Evolutional and Historical Backgrounds |journal=Nutrients |volume=7 |issue=9 |pages=7312–31 |year=2015 |pmid=26404364 |pmc=4586535 |doi=10.3390/nu7095340 |url=}}</ref><ref name="pmid27882862">{{cite journal |vauthors=Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A |title=Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence |journal=Food Nutr Res |volume=60 |issue= |pages=32527 |year=2016 |pmid=27882862 |pmc=5122229 |doi= |url=}}</ref> | ||
**Osteopenia | **[[Osteopenia]] | ||
**Osteoporosis | **[[Osteoporosis]] | ||
**Malnutrition | **[[Malnutrition]] | ||
**Rickets | **[[Rickets]] | ||
**Osteomalacia | **[[Osteomalacia]] | ||
===Prognosis=== | ===Prognosis=== | ||
Revision as of 21:59, 14 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
Overview
If left untreated, patients with lactose intoelrance may progress to develop malnutrition, osteomalacia , and osteopenia. Common complications of lactose intoelrance include if they do not intake calcium
include osteoprosis, osteopenia, osteomalacia and malnutriotion. Prognosis is generally excellent.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of lactose intoelrance usually develop after age of 6 and start with symptoms such as:[1][2][3]
- Abdominal pain
- Flatulence
- Bloating
- Watery, frothy and bulky diarrhea
- If left untreated, patients with lactose intolerance may progress to develop:
Complications
- Common complications of lactose intolerance if they do not intake adequate quantities of dairy products and calcium include: [4][5][6]
Prognosis
- Prognosis is generally excellent
References
- ↑ Szilagyi A (2015). "Adult lactose digestion status and effects on disease". Can J Gastroenterol Hepatol. 29 (3): 149–56. PMC 4399375. PMID 25855879.
- ↑ Suarez FL, Savaiano DA, Levitt MD (1995). "A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance". N. Engl. J. Med. 333 (1): 1–4. doi:10.1056/NEJM199507063330101. PMID 7776987.
- ↑ Mattar R, de Campos Mazo DF, Carrilho FJ (2012). "Lactose intolerance: diagnosis, genetic, and clinical factors". Clin Exp Gastroenterol. 5: 113–21. doi:10.2147/CEG.S32368. PMC 3401057. PMID 22826639.
- ↑ Mattar R, de Campos Mazo DF, Carrilho FJ (2012). "Lactose intolerance: diagnosis, genetic, and clinical factors". Clin Exp Gastroenterol. 5: 113–21. doi:10.2147/CEG.S32368. PMC 3401057. PMID 22826639.
- ↑ Silanikove N, Leitner G, Merin U (2015). "The Interrelationships between Lactose Intolerance and the Modern Dairy Industry: Global Perspectives in Evolutional and Historical Backgrounds". Nutrients. 7 (9): 7312–31. doi:10.3390/nu7095340. PMC 4586535. PMID 26404364.
- ↑ Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A (2016). "Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence". Food Nutr Res. 60: 32527. PMC 5122229. PMID 27882862.