Barrett's esophagus endoscopic therapy: Difference between revisions
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Several [[endoscopic]] therapies are available to treat severe [[dysplasia]] and [[cancer]]. During these therapies, the Barrett’s lining is destroyed or the portion of the lining that has [[dysplasia]] or [[cancer]] is [[cut]] out. The goal of the treatment is to encourage [[normal]] [[esophageal]] [[tissue]] to replace the destroyed Barrett’s lining. [[Endoscopic]] therapies are performed at specialty centers by [[physicians]] with expertise in these procedures. | Several [[endoscopic]] therapies are available to treat severe [[dysplasia]] and [[cancer]]. During these therapies, the Barrett’s lining is destroyed or the portion of the lining that has [[dysplasia]] or [[cancer]] is [[cut]] out. The goal of the treatment is to encourage [[normal]] [[esophageal]] [[tissue]] to replace the destroyed Barrett’s lining. [[Endoscopic]] therapies are performed at specialty centers by [[physicians]] with expertise in these procedures. | ||
*'''[[Photodynamic therapy]] (PDT)''' : PDT uses a light-sensitizing agent called [[Photofrin]] and a [[laser]] to kill [[precancerous]] and [[cancerous]] [[cells]]. [[Photofrin]] is [[injected]] into a [[vein]] and the [[patient]] returns 48 hours later. The [[laser]] [[light]] is then passed through the [[endoscope]] and activates the [[Photofrin]] to destroy Barrett’s [[tissue]] in the [[esophagus]]. [[Complications]] of PDT include [[chest pain]], [[nausea]], sun [[sensitivity]] for several weeks, and esophageal strictures. | *'''[[Photodynamic therapy]] (PDT)''' : PDT uses a light-sensitizing agent called [[Photofrin]] and a [[laser]] to kill [[precancerous]] and [[cancerous]] [[cells]]. [[Photofrin]] is [[injected]] into a [[vein]] and the [[patient]] returns 48 hours later. The [[laser]] [[light]] is then passed through the [[endoscope]] and activates the [[Photofrin]] to destroy Barrett’s [[tissue]] in the [[esophagus]]. [[Complications]] of PDT include [[chest pain]], [[nausea]], sun [[sensitivity]] for several weeks, and esophageal strictures. | ||
*''' | *'''Endoscopic mucosal resection (EMR)''': EMR involves lifting the Barrett’s lining and injecting a [[solution]] under it or applying [[suction]] to it and then cutting it off. The lining is then removed through the [[endoscope]]. If EMR is used to treat [[cancer]], an [[endoscopic ultrasound]] is [[done]] first to make sure the [[cancer]] involves only the top layer of [[esophageal]] [[cells]]. The [[ultrasound]] uses [[sound waves]] that bounce off the walls of the [[esophagus]] to create a picture on a monitor. [[Complications]] of EMR can include [[bleeding]] or tearing of the [[esophagus]]. EMR is sometimes used in combination with PDT. | ||
==References== | ==References== | ||
Revision as of 20:35, 15 December 2017
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Barrett's Esophagus Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Barrett's esophagus endoscopic therapy On the Web |
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American Roentgen Ray Society Images of Barrett's esophagus endoscopic therapy |
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Risk calculators and risk factors for Barrett's esophagus endoscopic therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: ; Amresh Kumar MD [2]
Overview
Endoscopic Therapy
Several endoscopic therapies are available to treat severe dysplasia and cancer. During these therapies, the Barrett’s lining is destroyed or the portion of the lining that has dysplasia or cancer is cut out. The goal of the treatment is to encourage normal esophageal tissue to replace the destroyed Barrett’s lining. Endoscopic therapies are performed at specialty centers by physicians with expertise in these procedures.
- Photodynamic therapy (PDT) : PDT uses a light-sensitizing agent called Photofrin and a laser to kill precancerous and cancerous cells. Photofrin is injected into a vein and the patient returns 48 hours later. The laser light is then passed through the endoscope and activates the Photofrin to destroy Barrett’s tissue in the esophagus. Complications of PDT include chest pain, nausea, sun sensitivity for several weeks, and esophageal strictures.
- Endoscopic mucosal resection (EMR): EMR involves lifting the Barrett’s lining and injecting a solution under it or applying suction to it and then cutting it off. The lining is then removed through the endoscope. If EMR is used to treat cancer, an endoscopic ultrasound is done first to make sure the cancer involves only the top layer of esophageal cells. The ultrasound uses sound waves that bounce off the walls of the esophagus to create a picture on a monitor. Complications of EMR can include bleeding or tearing of the esophagus. EMR is sometimes used in combination with PDT.