Gastrointestinal stromal tumor history and symptoms: Difference between revisions
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{{CMG}}{{AE}}{{PSD}} | {{CMG}}{{AE}}{{PSD}} | ||
==Overview== | ==Overview== | ||
Obtaining history is an important aspect in making a diagnosis of GIST. The areas of focus should be on onset, duration, and progression of symptoms such as abdominal pain, constipation, appetite, | Obtaining [[History and Physical examination|history]] is an important aspect in making a diagnosis of gastrointestinal stromal tumors (GIST). The areas of focus should be on onset, duration, and progression of symptoms such as [[abdominal pain]], [[constipation]], change in [[appetite]], and black stools. The symptoms of GISTs depends upon the [[tumor]] size and location. Majority of the GISTs are [[asymptomatic]]. Patients with GIST who have symptoms ([[tumor]] size > 5cm) are generally non specific such as [[dysphagia]], vague [[Abdominal discomfort|abdominal discomfort,]] [[jaundice]] and [[abdominal fullness]]. | ||
and black stools. The symptoms of GISTs depends upon the tumor size and location. Majority of the GISTs are asymptomatic. Patients with GIST who have symptoms (tumor size > 5cm) are generally non specific such as dysphagia, vague abdominal discomfort, jaundice and abdominal fullness. | |||
==History== | ==History== | ||
Obtaining history is an important aspect in making a diagnosis of GIST. It provides an insight into severity, precipitating factors and associated comorbid conditions. Complete history will help determine the correct therapy and helps in determining the prognosis. Rarely, GIST patients presenting in emergency room may be disoriented and the patient interview may be difficult. In such cases history from the care givers or the family members may need to be obtained. The areas of focus should be on onset, duration, and progression of symptoms such as | Obtaining [[History and Physical examination|history]] is an important aspect in making a diagnosis of GIST. It provides an insight into severity, precipitating factors and associated [[comorbid]] conditions. Complete [[History and Physical examination|history]] will help determine the correct [[therapy]] and helps in determining the prognosis. Rarely, GIST patients presenting in [[emergency room]] may be [[Disorientation|disoriented]] and the patient interview may be difficult. In such cases history from the care givers or the family members may need to be obtained. The areas of focus should be on onset, duration, and progression of symptoms such as: | ||
*Abdominal pain | *[[Abdominal pain]] | ||
*Constipation | *[[Constipation]] | ||
*Appetite | *[[Appetite]] changes | ||
*Black stools | *Black stools | ||
*Hematemesis | *[[Hematemesis]] | ||
*Drug intake such as NSAIDs | *Drug intake such as [[NSAIDs]] | ||
*Previous medical history (such as bleeding disorders) | *Previous medical history (such as [[bleeding disorders]]) | ||
==Symptoms== | ==Symptoms== | ||
===Common Symptoms=== | ===Common Symptoms=== | ||
* The symptoms of GISTs depends upon the tumor size and location. | * The symptoms of GISTs depends upon the [[tumor]] size and location. | ||
* Majority of the GISTs are asymptomatic. Patients with GIST who have symptoms (tumor size > 5cm) are generally non specific. | * Majority of the GISTs are [[asymptomatic]]. Patients with GIST who have symptoms ([[tumor]] size > 5cm) are generally non specific. | ||
* Following are the common symptoms seen in patients of GIST: | * Following are the common symptoms seen in patients of GIST: | ||
** [[Dysphagia]] (esophageal GIST) | ** [[Dysphagia]] (esophageal GIST) | ||
** [[Gastrointestinal hemorrhage]] presenting with black stools or hematemesis | ** [[Gastrointestinal hemorrhage]] presenting with black stools or [[hematemesis]] | ||
** Vague [[abdominal pain]] or discomfort | ** Vague [[abdominal pain]] or discomfort | ||
** Constipation (colorectal GIST) | ** [[Constipation]] (colorectal GIST) | ||
** Jaundice (duodenal GIST) | ** [[Jaundice]] (duodenal GIST) | ||
** Abdominal fullness | ** [[Abdominal fullness]] | ||
** Nausea | ** [[Nausea]] | ||
** Anorexia | ** [[Anorexia]] | ||
** Weight loss | ** [[Weight loss]] | ||
===Less Common Symptoms=== | ===Less Common Symptoms=== | ||
Intra-abdominal hemorrhage is uncommon, but when it occurs, can lead to symptoms | Intra-abdominal [[hemorrhage]] is uncommon, but when it occurs, can lead to symptoms such as: | ||
*Malaise | *[[Malaise]] | ||
*Fatigue | *[[Fatigue]] | ||
*Dyspnea | *[[Dyspnea]] | ||
==References== | ==References== | ||
Revision as of 21:03, 15 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
Obtaining history is an important aspect in making a diagnosis of gastrointestinal stromal tumors (GIST). The areas of focus should be on onset, duration, and progression of symptoms such as abdominal pain, constipation, change in appetite, and black stools. The symptoms of GISTs depends upon the tumor size and location. Majority of the GISTs are asymptomatic. Patients with GIST who have symptoms (tumor size > 5cm) are generally non specific such as dysphagia, vague abdominal discomfort, jaundice and abdominal fullness.
History
Obtaining history is an important aspect in making a diagnosis of GIST. It provides an insight into severity, precipitating factors and associated comorbid conditions. Complete history will help determine the correct therapy and helps in determining the prognosis. Rarely, GIST patients presenting in emergency room may be disoriented and the patient interview may be difficult. In such cases history from the care givers or the family members may need to be obtained. The areas of focus should be on onset, duration, and progression of symptoms such as:
- Abdominal pain
- Constipation
- Appetite changes
- Black stools
- Hematemesis
- Drug intake such as NSAIDs
- Previous medical history (such as bleeding disorders)
Symptoms
Common Symptoms
- The symptoms of GISTs depends upon the tumor size and location.
- Majority of the GISTs are asymptomatic. Patients with GIST who have symptoms (tumor size > 5cm) are generally non specific.
- Following are the common symptoms seen in patients of GIST:
- Dysphagia (esophageal GIST)
- Gastrointestinal hemorrhage presenting with black stools or hematemesis
- Vague abdominal pain or discomfort
- Constipation (colorectal GIST)
- Jaundice (duodenal GIST)
- Abdominal fullness
- Nausea
- Anorexia
- Weight loss
Less Common Symptoms
Intra-abdominal hemorrhage is uncommon, but when it occurs, can lead to symptoms such as: