Portal vein thrombosis laboratory findings: Difference between revisions
Jump to navigation
Jump to search
Farima Kahe (talk | contribs) |
Farima Kahe (talk | contribs) |
||
| Line 8: | Line 8: | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
*Laboratory findings of portal vein thrombosis will be normal or quite normal, unless there is coexistence of a liver disease. Although, [[coagulation factors]] levels could be moderately decreased, while [[D-dimer]] level is usually increased.<ref name="pmid20066733">{{cite journal |vauthors=Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A |title=Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment |journal=World J. Gastroenterol. |volume=16 |issue=2 |pages=143–55 |year=2010 |pmid=20066733 |pmc=2806552 |doi= |url=}}</ref><ref name="pmid16951667">{{cite journal |vauthors=Condat B, Valla D |title=Nonmalignant portal vein thrombosis in adults |journal=Nat Clin Pract Gastroenterol Hepatol |volume=3 |issue=9 |pages=505–15 |year=2006 |pmid=16951667 |doi=10.1038/ncpgasthep0577 |url=}}</ref><ref name="pmid2806552">{{cite journal |vauthors=Zhang WW, Churchill S, Churchill P |title=Developmental regulation of D-beta-hydroxybutyrate dehydrogenase in rat liver and brain |journal=FEBS Lett. |volume=256 |issue=1-2 |pages=71–4 |year=1989 |pmid=2806552 |doi= |url=}}</ref> | *Laboratory findings of portal vein thrombosis will be normal or quite normal, unless there is coexistence of a liver disease. Although, [[coagulation factors]] levels could be moderately decreased, while [[D-dimer]] level is usually increased. Im some patients laboratory findings may show moderate increase in serum aminotransferases.<ref name="pmid20066733">{{cite journal |vauthors=Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A |title=Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment |journal=World J. Gastroenterol. |volume=16 |issue=2 |pages=143–55 |year=2010 |pmid=20066733 |pmc=2806552 |doi= |url=}}</ref><ref name="pmid16951667">{{cite journal |vauthors=Condat B, Valla D |title=Nonmalignant portal vein thrombosis in adults |journal=Nat Clin Pract Gastroenterol Hepatol |volume=3 |issue=9 |pages=505–15 |year=2006 |pmid=16951667 |doi=10.1038/ncpgasthep0577 |url=}}</ref><ref name="pmid2806552">{{cite journal |vauthors=Zhang WW, Churchill S, Churchill P |title=Developmental regulation of D-beta-hydroxybutyrate dehydrogenase in rat liver and brain |journal=FEBS Lett. |volume=256 |issue=1-2 |pages=71–4 |year=1989 |pmid=2806552 |doi= |url=}}</ref> | ||
*In patients with cirrhosis, laboratory findings may demonstrate an elevated bilirubin, low platelet count, prolonged international normalized ratio (INR), or renal insufficiency. | |||
*Blood cultures of septic portal vein are often positive for Bacteroides fragilis or Escherichia coli, also other pathogens have been cultured.{{cite journal |vauthors=Plemmons RM, Dooley DP, Longfield RN |title=Septic thrombophlebitis of the portal vein (pylephlebitis): diagnosis and management in the modern era |journal=Clin. Infect. Dis. |volume=21 |issue=5 |pages=1114–20 |year=1995 |pmid=8589130 |doi= |url=}} | |||
==References== | ==References== | ||
Revision as of 15:56, 19 December 2017
|
Portal vein thrombosis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Portal vein thrombosis laboratory findings On the Web |
|
American Roentgen Ray Society Images of Portal vein thrombosis laboratory findings |
|
Risk calculators and risk factors for Portal vein thrombosis laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
Laboratory finding is usually normal among patients with portal vein thrombosis.
Laboratory Findings
- Laboratory findings of portal vein thrombosis will be normal or quite normal, unless there is coexistence of a liver disease. Although, coagulation factors levels could be moderately decreased, while D-dimer level is usually increased. Im some patients laboratory findings may show moderate increase in serum aminotransferases.[1][2][3]
- In patients with cirrhosis, laboratory findings may demonstrate an elevated bilirubin, low platelet count, prolonged international normalized ratio (INR), or renal insufficiency.
- Blood cultures of septic portal vein are often positive for Bacteroides fragilis or Escherichia coli, also other pathogens have been cultured.Plemmons RM, Dooley DP, Longfield RN (1995). "Septic thrombophlebitis of the portal vein (pylephlebitis): diagnosis and management in the modern era". Clin. Infect. Dis. 21 (5): 1114–20. PMID 8589130.
References
- ↑ Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A (2010). "Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment". World J. Gastroenterol. 16 (2): 143–55. PMC 2806552. PMID 20066733.
- ↑ Condat B, Valla D (2006). "Nonmalignant portal vein thrombosis in adults". Nat Clin Pract Gastroenterol Hepatol. 3 (9): 505–15. doi:10.1038/ncpgasthep0577. PMID 16951667.
- ↑ Zhang WW, Churchill S, Churchill P (1989). "Developmental regulation of D-beta-hydroxybutyrate dehydrogenase in rat liver and brain". FEBS Lett. 256 (1–2): 71–4. PMID 2806552.